| Motif | E2F6.H12RSNP.0.P.B |
| Gene (human) | E2F6 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | E2f6 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | E2F6.H12RSNP.0.P.B |
| Gene (human) | E2F6 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | E2f6 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 12 |
| Consensus | dKRGMGGGARvn |
| GC content | 64.08% |
| Information content (bits; total / per base) | 11.601 / 0.967 |
| Data sources | ChIP-Seq |
| Aligned words | 148 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 7 (49) | 0.735 | 0.835 | 0.594 | 0.736 | 0.771 | 0.857 | 2.385 | 2.963 | 87.469 | 230.886 |
| Mouse | 1 (7) | 0.854 | 0.87 | 0.737 | 0.771 | 0.852 | 0.858 | 2.918 | 2.996 | 255.31 | 283.071 |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 16.577 | 3.397 | 0.282 | 0.17 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | E2F {3.3.2} (TFClass) |
| TF subfamily | E2F {3.3.2.1} (TFClass) |
| TFClass ID | TFClass: 3.3.2.1.6 |
| HGNC | HGNC:3120 |
| MGI | MGI:1354159 |
| EntrezGene (human) | GeneID:1876 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:50496 (SSTAR profile) |
| UniProt ID (human) | E2F6_HUMAN |
| UniProt ID (mouse) | E2F6_MOUSE |
| UniProt AC (human) | O75461 (TFClass) |
| UniProt AC (mouse) | O54917 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 7 human, 1 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | E2F6.H12RSNP.0.P.B.pcm |
| PWM | E2F6.H12RSNP.0.P.B.pwm |
| PFM | E2F6.H12RSNP.0.P.B.pfm |
| Alignment | E2F6.H12RSNP.0.P.B.words.tsv |
| Threshold to P-value map | E2F6.H12RSNP.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | E2F6.H12RSNP.0.P.B_jaspar_format.txt |
| MEME format | E2F6.H12RSNP.0.P.B_meme_format.meme |
| Transfac format | E2F6.H12RSNP.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 62.0 | 22.0 | 30.0 | 34.0 |
| 02 | 29.0 | 4.0 | 80.0 | 35.0 |
| 03 | 26.0 | 22.0 | 96.0 | 4.0 |
| 04 | 0.0 | 2.0 | 144.0 | 2.0 |
| 05 | 29.0 | 104.0 | 3.0 | 12.0 |
| 06 | 7.0 | 0.0 | 134.0 | 7.0 |
| 07 | 0.0 | 1.0 | 145.0 | 2.0 |
| 08 | 1.0 | 5.0 | 142.0 | 0.0 |
| 09 | 143.0 | 4.0 | 1.0 | 0.0 |
| 10 | 110.0 | 7.0 | 27.0 | 4.0 |
| 11 | 56.0 | 24.0 | 52.0 | 16.0 |
| 12 | 37.0 | 39.0 | 50.0 | 22.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.419 | 0.149 | 0.203 | 0.23 |
| 02 | 0.196 | 0.027 | 0.541 | 0.236 |
| 03 | 0.176 | 0.149 | 0.649 | 0.027 |
| 04 | 0.0 | 0.014 | 0.973 | 0.014 |
| 05 | 0.196 | 0.703 | 0.02 | 0.081 |
| 06 | 0.047 | 0.0 | 0.905 | 0.047 |
| 07 | 0.0 | 0.007 | 0.98 | 0.014 |
| 08 | 0.007 | 0.034 | 0.959 | 0.0 |
| 09 | 0.966 | 0.027 | 0.007 | 0.0 |
| 10 | 0.743 | 0.047 | 0.182 | 0.027 |
| 11 | 0.378 | 0.162 | 0.351 | 0.108 |
| 12 | 0.25 | 0.264 | 0.338 | 0.149 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.503 | -0.498 | -0.202 | -0.082 |
| 02 | -0.235 | -1.986 | 0.753 | -0.054 |
| 03 | -0.339 | -0.498 | 0.933 | -1.986 |
| 04 | -3.422 | -2.466 | 1.334 | -2.466 |
| 05 | -0.235 | 1.012 | -2.197 | -1.06 |
| 06 | -1.534 | -3.422 | 1.263 | -1.534 |
| 07 | -3.422 | -2.834 | 1.341 | -2.466 |
| 08 | -2.834 | -1.812 | 1.32 | -3.422 |
| 09 | 1.327 | -1.986 | -2.834 | -3.422 |
| 10 | 1.068 | -1.534 | -0.303 | -1.986 |
| 11 | 0.403 | -0.415 | 0.331 | -0.796 |
| 12 | 0.0 | 0.051 | 0.293 | -0.498 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.508265 |
| 0.0005 | 5.422015 |
| 0.0001 | 7.303355 |