E2F6.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F6.H12INVIVO.0.P.B
Gene (human)	E2F6 (GeneCards)
Gene synonyms (human)
Gene (mouse)	E2f6
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	ndSGCGGGARv
GC content	67.06%
Information content (bits; total / per base)	12.057 / 1.096
Data sources	ChIP-Seq
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (49)	0.764	0.834	0.628	0.75	0.774	0.832	2.435	2.836	107.456	252.538
Mouse	1 (7)	0.883	0.898	0.78	0.811	0.864	0.869	3.038	3.115	320.367	355.658

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	7.382	2.364	0.277	0.173

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.6
HGNC	HGNC:3120
MGI	MGI:1354159
EntrezGene (human)	GeneID:1876 (SSTAR profile)
EntrezGene (mouse)	GeneID:50496 (SSTAR profile)
UniProt ID (human)	E2F6_HUMAN
UniProt ID (mouse)	E2F6_MOUSE
UniProt AC (human)	O75461 (TFClass)
UniProt AC (mouse)	O54917 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	E2F6.H12INVIVO.0.P.B.pcm
PWM	E2F6.H12INVIVO.0.P.B.pwm
PFM	E2F6.H12INVIVO.0.P.B.pfm
Alignment	E2F6.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	E2F6.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	E2F6.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	E2F6.H12INVIVO.0.P.B_meme_format.meme
Transfac format	E2F6.H12INVIVO.0.P.B_transfac_format.txt
Homer format	E2F6.H12INVIVO.0.P.B_homer_format_0.001.txt E2F6.H12INVIVO.0.P.B_homer_format_0.0005.txt E2F6.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	311.0	180.0	295.0	212.0
02	279.0	65.0	388.0	266.0
03	159.0	174.0	661.0	4.0
04	2.0	6.0	989.0	1.0
05	95.0	852.0	22.0	29.0
06	21.0	6.0	964.0	7.0
07	1.0	9.0	984.0	4.0
08	8.0	34.0	943.0	13.0
09	961.0	18.0	9.0	10.0
10	719.0	45.0	222.0	12.0
11	395.0	200.0	296.0	107.0

PFM

	A	C	G	T
01	0.312	0.18	0.296	0.212
02	0.28	0.065	0.389	0.267
03	0.159	0.174	0.662	0.004
04	0.002	0.006	0.991	0.001
05	0.095	0.854	0.022	0.029
06	0.021	0.006	0.966	0.007
07	0.001	0.009	0.986	0.004
08	0.008	0.034	0.945	0.013
09	0.963	0.018	0.009	0.01
10	0.72	0.045	0.222	0.012
11	0.396	0.2	0.297	0.107

PWM

	A	C	G	T
01	0.219	-0.324	0.166	-0.162
02	0.111	-1.326	0.439	0.064
03	-0.447	-0.357	0.97	-3.781
04	-4.211	-3.482	1.372	-4.523
05	-0.954	1.223	-2.36	-2.101
06	-2.403	-3.482	1.347	-3.36
07	-4.523	-3.154	1.367	-3.781
08	-3.252	-1.95	1.325	-2.837
09	1.343	-2.544	-3.154	-3.065
10	1.054	-1.682	-0.116	-2.907
11	0.457	-0.219	0.17	-0.838

Standard thresholds

P-value	Threshold
0.001	4.055325
0.0005	5.07653
0.0001	7.22844