MotifE2F4.H12CORE.2.S.B
Gene (human)E2F4
(GeneCards)
Gene synonyms (human)
Gene (mouse)E2f4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length16
ConsensusnndWdTGGCGCShhhn
GC content57.33%
Information content (bits; total / per base)14.174 / 0.886
Data sourcesHT-SELEX
Aligned words9628

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (56) 0.718 0.765 0.507 0.554 0.547 0.623 1.22 1.444 23.149 38.854
Mouse 12 (81) 0.757 0.8 0.573 0.642 0.55 0.612 1.299 1.505 19.276 58.137

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.756 0.758 0.752 0.751 0.742 0.74
best 0.999 0.998 0.996 0.994 0.979 0.975

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.57 0.105 0.352 0.215
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyE2F {3.3.2} (TFClass)
TF subfamilyE2F {3.3.2.1} (TFClass)
TFClass IDTFClass: 3.3.2.1.4
HGNCHGNC:3118
MGIMGI:103012
EntrezGene (human)GeneID:1874
(SSTAR profile)
EntrezGene (mouse)GeneID:104394
(SSTAR profile)
UniProt ID (human)E2F4_HUMAN
UniProt ID (mouse)E2F4_MOUSE
UniProt AC (human)Q16254
(TFClass)
UniProt AC (mouse)Q8R0K9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 12 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
012689.02271.02524.02144.0
022856.751735.752898.752136.75
033036.01088.01788.03716.0
043844.0548.0818.04418.0
053111.0222.02225.04070.0
0645.00.044.09539.0
076.01.09621.00.0
081.00.09627.00.0
092.09626.00.00.0
101.00.09627.00.0
113.09566.056.03.0
125.05320.03831.0472.0
134226.03345.0507.01550.0
141688.02092.01269.04579.0
152324.251747.251421.254135.25
162158.02120.02378.02972.0
PFM
ACGT
010.2790.2360.2620.223
020.2970.180.3010.222
030.3150.1130.1860.386
040.3990.0570.0850.459
050.3230.0230.2310.423
060.0050.00.0050.991
070.0010.00.9990.0
080.00.01.00.0
090.01.00.00.0
100.00.01.00.0
110.00.9940.0060.0
120.0010.5530.3980.049
130.4390.3470.0530.161
140.1750.2170.1320.476
150.2410.1810.1480.43
160.2240.220.2470.309
PWM
ACGT
010.111-0.0580.047-0.116
020.171-0.3270.186-0.119
030.232-0.793-0.2970.434
040.468-1.477-1.0770.607
050.256-2.374-0.0790.525
06-3.931-6.957-3.9521.376
07-5.672-6.5951.385-6.957
08-6.595-6.9571.385-6.957
09-6.331.385-6.957-6.957
10-6.595-6.9571.385-6.957
11-6.1211.379-3.722-6.121
12-5.80.7930.464-1.625
130.5620.329-1.554-0.44
14-0.354-0.14-0.6390.643
15-0.035-0.32-0.5260.541
16-0.109-0.127-0.0120.211
Standard thresholds
P-value Threshold
0.001 0.96991
0.0005 2.37976
0.0001 6.63901