E2F4.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F4.H12CORE.0.P.B
Gene (human)	E2F4 (GeneCards)
Gene synonyms (human)
Gene (mouse)	E2f4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	SGCGSSMddWYbdvd
GC content	58.65%
Information content (bits; total / per base)	9.792 / 0.653
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (56)	0.858	0.913	0.754	0.866	0.773	0.853	2.544	3.772	148.745	283.337
Mouse	12 (81)	0.85	0.898	0.736	0.804	0.73	0.808	2.184	2.799	117.921	290.174

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.729	0.709	0.724	0.703	0.712	0.691
Non-Methyl HT-SELEX, 2 experiments	best	0.952	0.915	0.943	0.904	0.921	0.881

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.553	0.104	0.219	0.14

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.4
HGNC	HGNC:3118
MGI	MGI:103012
EntrezGene (human)	GeneID:1874 (SSTAR profile)
EntrezGene (mouse)	GeneID:104394 (SSTAR profile)
UniProt ID (human)	E2F4_HUMAN
UniProt ID (mouse)	E2F4_MOUSE
UniProt AC (human)	Q16254 (TFClass)
UniProt AC (mouse)	Q8R0K9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 12 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	E2F4.H12CORE.0.P.B.pcm
PWM	E2F4.H12CORE.0.P.B.pwm
PFM	E2F4.H12CORE.0.P.B.pfm
Alignment	E2F4.H12CORE.0.P.B.words.tsv
Threshold to P-value map	E2F4.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	E2F4.H12CORE.0.P.B_jaspar_format.txt
MEME format	E2F4.H12CORE.0.P.B_meme_format.meme
Transfac format	E2F4.H12CORE.0.P.B_transfac_format.txt
Homer format	E2F4.H12CORE.0.P.B_homer_format_0.001.txt E2F4.H12CORE.0.P.B_homer_format_0.0005.txt E2F4.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	107.0	297.0	574.0	21.0
02	3.0	81.0	909.0	6.0
03	45.0	934.0	8.0	12.0
04	13.0	15.0	936.0	35.0
05	6.0	321.0	662.0	10.0
06	54.0	158.0	737.0	50.0
07	603.0	173.0	146.0	77.0
08	484.0	142.0	229.0	144.0
09	388.0	109.0	215.0	287.0
10	178.0	102.0	118.0	601.0
11	113.0	145.0	97.0	644.0
12	67.0	311.0	204.0	417.0
13	329.0	116.0	407.0	147.0
14	559.0	94.0	255.0	91.0
15	556.0	109.0	185.0	149.0

PFM

	A	C	G	T
01	0.107	0.297	0.575	0.021
02	0.003	0.081	0.91	0.006
03	0.045	0.935	0.008	0.012
04	0.013	0.015	0.937	0.035
05	0.006	0.321	0.663	0.01
06	0.054	0.158	0.738	0.05
07	0.604	0.173	0.146	0.077
08	0.484	0.142	0.229	0.144
09	0.388	0.109	0.215	0.287
10	0.178	0.102	0.118	0.602
11	0.113	0.145	0.097	0.645
12	0.067	0.311	0.204	0.417
13	0.329	0.116	0.407	0.147
14	0.56	0.094	0.255	0.091
15	0.557	0.109	0.185	0.149

PWM

	A	C	G	T
01	-0.839	0.172	0.828	-2.404
02	-3.974	-1.112	1.287	-3.483
03	-1.683	1.314	-3.252	-2.908
04	-2.838	-2.71	1.316	-1.924
05	-3.483	0.249	0.971	-3.065
06	-1.507	-0.454	1.078	-1.581
07	0.877	-0.364	-0.532	-1.161
08	0.658	-0.559	-0.086	-0.546
09	0.438	-0.82	-0.149	0.138
10	-0.336	-0.886	-0.742	0.874
11	-0.785	-0.539	-0.935	0.943
12	-1.297	0.218	-0.201	0.51
13	0.274	-0.759	0.486	-0.525
14	0.802	-0.966	0.021	-0.998
15	0.797	-0.82	-0.298	-0.512

Standard thresholds

P-value	Threshold
0.001	4.78536
0.0005	5.59071
0.0001	7.21601