Motif | E2F3.H12RSNP.1.SM.D |
Gene (human) | E2F3 (GeneCards) |
Gene synonyms (human) | KIAA0075 |
Gene (mouse) | E2f3 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | D |
Motif | E2F3.H12RSNP.1.SM.D |
Gene (human) | E2F3 (GeneCards) |
Gene synonyms (human) | KIAA0075 |
Gene (mouse) | E2f3 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | D |
Motif length | 15 |
Consensus | hWKGGCGCCAAAAhn |
GC content | 49.54% |
Information content (bits; total / per base) | 17.081 / 1.139 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 276 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 7 (37) | 0.572 | 0.8 | 0.456 | 0.618 | 0.393 | 0.516 | 0.856 | 1.225 | 15.721 | 59.921 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.791 | 0.796 | 0.659 | 0.672 | 0.582 | 0.603 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.997 | 0.996 | |
Methyl HT-SELEX, 1 experiments | median | 0.914 | 0.907 | 0.744 | 0.751 | 0.631 | 0.653 |
best | 0.914 | 0.907 | 0.744 | 0.751 | 0.631 | 0.653 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.667 | 0.685 | 0.573 | 0.593 | 0.534 | 0.552 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.997 | 0.996 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Fork head/winged helix factors {3.3} (TFClass) |
TF family | E2F {3.3.2} (TFClass) |
TF subfamily | E2F {3.3.2.1} (TFClass) |
TFClass ID | TFClass: 3.3.2.1.3 |
HGNC | HGNC:3115 |
MGI | MGI:1096340 |
EntrezGene (human) | GeneID:1871 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13557 (SSTAR profile) |
UniProt ID (human) | E2F3_HUMAN |
UniProt ID (mouse) | E2F3_MOUSE |
UniProt AC (human) | O00716 (TFClass) |
UniProt AC (mouse) | O35261 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 7 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | E2F3.H12RSNP.1.SM.D.pcm |
PWM | E2F3.H12RSNP.1.SM.D.pwm |
PFM | E2F3.H12RSNP.1.SM.D.pfm |
Alignment | E2F3.H12RSNP.1.SM.D.words.tsv |
Threshold to P-value map | E2F3.H12RSNP.1.SM.D.thr |
Motif in other formats | |
JASPAR format | E2F3.H12RSNP.1.SM.D_jaspar_format.txt |
MEME format | E2F3.H12RSNP.1.SM.D_meme_format.meme |
Transfac format | E2F3.H12RSNP.1.SM.D_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 132.5 | 24.5 | 18.5 | 100.5 |
02 | 139.0 | 4.0 | 14.0 | 119.0 |
03 | 54.0 | 0.0 | 71.0 | 151.0 |
04 | 0.0 | 80.0 | 196.0 | 0.0 |
05 | 0.0 | 0.0 | 276.0 | 0.0 |
06 | 0.0 | 276.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 276.0 | 0.0 |
08 | 0.0 | 276.0 | 0.0 | 0.0 |
09 | 0.0 | 240.0 | 36.0 | 0.0 |
10 | 238.0 | 25.0 | 1.0 | 12.0 |
11 | 220.0 | 0.0 | 3.0 | 53.0 |
12 | 232.0 | 5.0 | 11.0 | 28.0 |
13 | 224.0 | 6.0 | 7.0 | 39.0 |
14 | 97.25 | 57.25 | 31.25 | 90.25 |
15 | 77.75 | 58.75 | 57.75 | 81.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.48 | 0.089 | 0.067 | 0.364 |
02 | 0.504 | 0.014 | 0.051 | 0.431 |
03 | 0.196 | 0.0 | 0.257 | 0.547 |
04 | 0.0 | 0.29 | 0.71 | 0.0 |
05 | 0.0 | 0.0 | 1.0 | 0.0 |
06 | 0.0 | 1.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 1.0 | 0.0 |
08 | 0.0 | 1.0 | 0.0 | 0.0 |
09 | 0.0 | 0.87 | 0.13 | 0.0 |
10 | 0.862 | 0.091 | 0.004 | 0.043 |
11 | 0.797 | 0.0 | 0.011 | 0.192 |
12 | 0.841 | 0.018 | 0.04 | 0.101 |
13 | 0.812 | 0.022 | 0.025 | 0.141 |
14 | 0.352 | 0.207 | 0.113 | 0.327 |
15 | 0.282 | 0.213 | 0.209 | 0.296 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.643 | -1.0 | -1.263 | 0.37 |
02 | 0.69 | -2.567 | -1.52 | 0.537 |
03 | -0.24 | -3.914 | 0.028 | 0.772 |
04 | -3.914 | 0.145 | 1.031 | -3.914 |
05 | -3.914 | -3.914 | 1.371 | -3.914 |
06 | -3.914 | 1.371 | -3.914 | -3.914 |
07 | -3.914 | -3.914 | 1.371 | -3.914 |
08 | -3.914 | 1.371 | -3.914 | -3.914 |
09 | -3.914 | 1.232 | -0.632 | -3.914 |
10 | 1.224 | -0.981 | -3.377 | -1.659 |
11 | 1.146 | -3.914 | -2.772 | -0.258 |
12 | 1.199 | -2.397 | -1.736 | -0.873 |
13 | 1.164 | -2.252 | -2.125 | -0.555 |
14 | 0.337 | -0.183 | -0.768 | 0.264 |
15 | 0.117 | -0.157 | -0.174 | 0.166 |
P-value | Threshold |
---|---|
0.001 | 1.81371 |
0.0005 | 3.17926 |
0.0001 | 6.02166 |