MotifE2F3.H12RSNP.1.SM.D
Gene (human)E2F3
(GeneCards)
Gene synonyms (human)KIAA0075
Gene (mouse)E2f3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length15
ConsensushWKGGCGCCAAAAhn
GC content49.54%
Information content (bits; total / per base)17.081 / 1.139
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words276

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 7 (37) 0.572 0.8 0.456 0.618 0.393 0.516 0.856 1.225 15.721 59.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.791 0.796 0.659 0.672 0.582 0.603
best 1.0 1.0 1.0 1.0 0.997 0.996
Methyl HT-SELEX, 1 experiments median 0.914 0.907 0.744 0.751 0.631 0.653
best 0.914 0.907 0.744 0.751 0.631 0.653
Non-Methyl HT-SELEX, 3 experiments median 0.667 0.685 0.573 0.593 0.534 0.552
best 1.0 1.0 1.0 1.0 0.997 0.996
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyE2F {3.3.2} (TFClass)
TF subfamilyE2F {3.3.2.1} (TFClass)
TFClass IDTFClass: 3.3.2.1.3
HGNCHGNC:3115
MGIMGI:1096340
EntrezGene (human)GeneID:1871
(SSTAR profile)
EntrezGene (mouse)GeneID:13557
(SSTAR profile)
UniProt ID (human)E2F3_HUMAN
UniProt ID (mouse)E2F3_MOUSE
UniProt AC (human)O00716
(TFClass)
UniProt AC (mouse)O35261
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 7 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01132.524.518.5100.5
02139.04.014.0119.0
0354.00.071.0151.0
040.080.0196.00.0
050.00.0276.00.0
060.0276.00.00.0
070.00.0276.00.0
080.0276.00.00.0
090.0240.036.00.0
10238.025.01.012.0
11220.00.03.053.0
12232.05.011.028.0
13224.06.07.039.0
1497.2557.2531.2590.25
1577.7558.7557.7581.75
PFM
ACGT
010.480.0890.0670.364
020.5040.0140.0510.431
030.1960.00.2570.547
040.00.290.710.0
050.00.01.00.0
060.01.00.00.0
070.00.01.00.0
080.01.00.00.0
090.00.870.130.0
100.8620.0910.0040.043
110.7970.00.0110.192
120.8410.0180.040.101
130.8120.0220.0250.141
140.3520.2070.1130.327
150.2820.2130.2090.296
PWM
ACGT
010.643-1.0-1.2630.37
020.69-2.567-1.520.537
03-0.24-3.9140.0280.772
04-3.9140.1451.031-3.914
05-3.914-3.9141.371-3.914
06-3.9141.371-3.914-3.914
07-3.914-3.9141.371-3.914
08-3.9141.371-3.914-3.914
09-3.9141.232-0.632-3.914
101.224-0.981-3.377-1.659
111.146-3.914-2.772-0.258
121.199-2.397-1.736-0.873
131.164-2.252-2.125-0.555
140.337-0.183-0.7680.264
150.117-0.157-0.1740.166
Standard thresholds
P-value Threshold
0.001 1.81371
0.0005 3.17926
0.0001 6.02166