| Motif | E2F3.H12INVIVO.0.P.B |
| Gene (human) | E2F3 (GeneCards) |
| Gene synonyms (human) | KIAA0075 |
| Gene (mouse) | E2f3 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | E2F3.H12INVIVO.0.P.B |
| Gene (human) | E2F3 (GeneCards) |
| Gene synonyms (human) | KIAA0075 |
| Gene (mouse) | E2f3 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | dSGCGGGAR |
| GC content | 73.26% |
| Information content (bits; total / per base) | 10.636 / 1.182 |
| Data sources | ChIP-Seq |
| Aligned words | 986 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 7 (37) | 0.664 | 0.878 | 0.604 | 0.74 | 0.604 | 0.921 | 2.127 | 3.305 | 64.824 | 173.699 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.581 | 0.545 | 0.574 | 0.542 | 0.549 | 0.533 |
| best | 0.743 | 0.66 | 0.739 | 0.657 | 0.776 | 0.679 | |
| Methyl HT-SELEX, 1 experiments | median | 0.582 | 0.546 | 0.597 | 0.552 | 0.572 | 0.544 |
| best | 0.582 | 0.546 | 0.597 | 0.552 | 0.572 | 0.544 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.58 | 0.543 | 0.551 | 0.532 | 0.527 | 0.521 |
| best | 0.743 | 0.66 | 0.739 | 0.657 | 0.776 | 0.679 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | E2F {3.3.2} (TFClass) |
| TF subfamily | E2F {3.3.2.1} (TFClass) |
| TFClass ID | TFClass: 3.3.2.1.3 |
| HGNC | HGNC:3115 |
| MGI | MGI:1096340 |
| EntrezGene (human) | GeneID:1871 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:13557 (SSTAR profile) |
| UniProt ID (human) | E2F3_HUMAN |
| UniProt ID (mouse) | E2F3_MOUSE |
| UniProt AC (human) | O00716 (TFClass) |
| UniProt AC (mouse) | O35261 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 7 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | E2F3.H12INVIVO.0.P.B.pcm |
| PWM | E2F3.H12INVIVO.0.P.B.pwm |
| PFM | E2F3.H12INVIVO.0.P.B.pfm |
| Alignment | E2F3.H12INVIVO.0.P.B.words.tsv |
| Threshold to P-value map | E2F3.H12INVIVO.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | E2F3.H12INVIVO.0.P.B_jaspar_format.txt |
| MEME format | E2F3.H12INVIVO.0.P.B_meme_format.meme |
| Transfac format | E2F3.H12INVIVO.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 193.0 | 93.0 | 411.0 | 289.0 |
| 02 | 59.0 | 221.0 | 700.0 | 6.0 |
| 03 | 12.0 | 13.0 | 954.0 | 7.0 |
| 04 | 41.0 | 925.0 | 6.0 | 14.0 |
| 05 | 38.0 | 8.0 | 919.0 | 21.0 |
| 06 | 42.0 | 63.0 | 873.0 | 8.0 |
| 07 | 79.0 | 35.0 | 865.0 | 7.0 |
| 08 | 882.0 | 63.0 | 31.0 | 10.0 |
| 09 | 613.0 | 35.0 | 286.0 | 52.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.196 | 0.094 | 0.417 | 0.293 |
| 02 | 0.06 | 0.224 | 0.71 | 0.006 |
| 03 | 0.012 | 0.013 | 0.968 | 0.007 |
| 04 | 0.042 | 0.938 | 0.006 | 0.014 |
| 05 | 0.039 | 0.008 | 0.932 | 0.021 |
| 06 | 0.043 | 0.064 | 0.885 | 0.008 |
| 07 | 0.08 | 0.035 | 0.877 | 0.007 |
| 08 | 0.895 | 0.064 | 0.031 | 0.01 |
| 09 | 0.622 | 0.035 | 0.29 | 0.053 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.243 | -0.963 | 0.508 | 0.158 |
| 02 | -1.408 | -0.108 | 1.039 | -3.47 |
| 03 | -2.895 | -2.825 | 1.348 | -3.348 |
| 04 | -1.76 | 1.317 | -3.47 | -2.759 |
| 05 | -1.832 | -3.24 | 1.311 | -2.391 |
| 06 | -1.736 | -1.344 | 1.26 | -3.24 |
| 07 | -1.123 | -1.911 | 1.25 | -3.348 |
| 08 | 1.27 | -1.344 | -2.026 | -3.053 |
| 09 | 0.907 | -1.911 | 0.148 | -1.53 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.53054 |
| 0.0005 | 5.48238 |
| 0.0001 | 7.18027 |