E2F3.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F3.H12INVITRO.0.P.B
Gene (human)	E2F3 (GeneCards)
Gene synonyms (human)	KIAA0075
Gene (mouse)	E2f3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	ndSGCGGGARv
GC content	68.39%
Information content (bits; total / per base)	10.647 / 0.968
Data sources	ChIP-Seq
Aligned words	987

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	7 (37)	0.666	0.868	0.6	0.725	0.622	0.915	2.237	3.369	56.921	185.108

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.629	0.572	0.593	0.56	0.556	0.542
Overall, 4 experiments	best	0.762	0.681	0.807	0.707	0.834	0.735
Methyl HT-SELEX, 1 experiments	median	0.654	0.582	0.631	0.578	0.584	0.558
Methyl HT-SELEX, 1 experiments	best	0.654	0.582	0.631	0.578	0.584	0.558
Non-Methyl HT-SELEX, 3 experiments	median	0.603	0.563	0.556	0.541	0.528	0.526
Non-Methyl HT-SELEX, 3 experiments	best	0.762	0.681	0.807	0.707	0.834	0.735

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.3
HGNC	HGNC:3115
MGI	MGI:1096340
EntrezGene (human)	GeneID:1871 (SSTAR profile)
EntrezGene (mouse)	GeneID:13557 (SSTAR profile)
UniProt ID (human)	E2F3_HUMAN
UniProt ID (mouse)	E2F3_MOUSE
UniProt AC (human)	O00716 (TFClass)
UniProt AC (mouse)	O35261 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 7 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	E2F3.H12INVITRO.0.P.B.pcm
PWM	E2F3.H12INVITRO.0.P.B.pwm
PFM	E2F3.H12INVITRO.0.P.B.pfm
Alignment	E2F3.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	E2F3.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	E2F3.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	E2F3.H12INVITRO.0.P.B_meme_format.meme
Transfac format	E2F3.H12INVITRO.0.P.B_transfac_format.txt
Homer format	E2F3.H12INVITRO.0.P.B_homer_format_0.001.txt E2F3.H12INVITRO.0.P.B_homer_format_0.0005.txt E2F3.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	297.0	215.0	263.0	212.0
02	187.0	97.0	421.0	282.0
03	64.0	223.0	696.0	4.0
04	7.0	13.0	961.0	6.0
05	54.0	909.0	8.0	16.0
06	48.0	11.0	896.0	32.0
07	45.0	103.0	833.0	6.0
08	70.0	52.0	856.0	9.0
09	882.0	49.0	42.0	14.0
10	654.0	20.0	287.0	26.0
11	428.0	180.0	290.0	89.0

PFM

	A	C	G	T
01	0.301	0.218	0.266	0.215
02	0.189	0.098	0.427	0.286
03	0.065	0.226	0.705	0.004
04	0.007	0.013	0.974	0.006
05	0.055	0.921	0.008	0.016
06	0.049	0.011	0.908	0.032
07	0.046	0.104	0.844	0.006
08	0.071	0.053	0.867	0.009
09	0.894	0.05	0.043	0.014
10	0.663	0.02	0.291	0.026
11	0.434	0.182	0.294	0.09

PWM

	A	C	G	T
01	0.184	-0.137	0.063	-0.151
02	-0.275	-0.923	0.531	0.133
03	-1.33	-0.1	1.032	-3.771
04	-3.349	-2.826	1.354	-3.471
05	-1.495	1.299	-3.241	-2.64
06	-1.609	-2.972	1.285	-1.997
07	-1.671	-0.864	1.212	-3.471
08	-1.243	-1.531	1.239	-3.143
09	1.269	-1.589	-1.737	-2.76
10	0.97	-2.437	0.15	-2.193
11	0.548	-0.313	0.16	-1.008

Standard thresholds

P-value	Threshold
0.001	4.54682
0.0005	5.45108
0.0001	7.258145