MotifE2F3.H12CORE.0.P.B
Gene (human)E2F3
(GeneCards)
Gene synonyms (human)KIAA0075
Gene (mouse)E2f3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusndSGCGGGARv
GC content68.39%
Information content (bits; total / per base)10.647 / 0.968
Data sourcesChIP-Seq
Aligned words987

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 7 (37) 0.666 0.868 0.6 0.725 0.622 0.915 2.237 3.369 56.921 185.108

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.629 0.572 0.593 0.56 0.556 0.542
best 0.762 0.681 0.807 0.707 0.834 0.735
Methyl HT-SELEX, 1 experiments median 0.654 0.582 0.631 0.578 0.584 0.558
best 0.654 0.582 0.631 0.578 0.584 0.558
Non-Methyl HT-SELEX, 3 experiments median 0.603 0.563 0.556 0.541 0.528 0.526
best 0.762 0.681 0.807 0.707 0.834 0.735
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyE2F {3.3.2} (TFClass)
TF subfamilyE2F {3.3.2.1} (TFClass)
TFClass IDTFClass: 3.3.2.1.3
HGNCHGNC:3115
MGIMGI:1096340
EntrezGene (human)GeneID:1871
(SSTAR profile)
EntrezGene (mouse)GeneID:13557
(SSTAR profile)
UniProt ID (human)E2F3_HUMAN
UniProt ID (mouse)E2F3_MOUSE
UniProt AC (human)O00716
(TFClass)
UniProt AC (mouse)O35261
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 7 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01297.0215.0263.0212.0
02187.097.0421.0282.0
0364.0223.0696.04.0
047.013.0961.06.0
0554.0909.08.016.0
0648.011.0896.032.0
0745.0103.0833.06.0
0870.052.0856.09.0
09882.049.042.014.0
10654.020.0287.026.0
11428.0180.0290.089.0
PFM
ACGT
010.3010.2180.2660.215
020.1890.0980.4270.286
030.0650.2260.7050.004
040.0070.0130.9740.006
050.0550.9210.0080.016
060.0490.0110.9080.032
070.0460.1040.8440.006
080.0710.0530.8670.009
090.8940.050.0430.014
100.6630.020.2910.026
110.4340.1820.2940.09
PWM
ACGT
010.184-0.1370.063-0.151
02-0.275-0.9230.5310.133
03-1.33-0.11.032-3.771
04-3.349-2.8261.354-3.471
05-1.4951.299-3.241-2.64
06-1.609-2.9721.285-1.997
07-1.671-0.8641.212-3.471
08-1.243-1.5311.239-3.143
091.269-1.589-1.737-2.76
100.97-2.4370.15-2.193
110.548-0.3130.16-1.008
Standard thresholds
P-value Threshold
0.001 4.54682
0.0005 5.45108
0.0001 7.258145