E2F2.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F2.H12INVITRO.0.S.B
Gene (human)	E2F2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	E2f2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	nvddWTGGCGCSMdhb
GC content	61.41%
Information content (bits; total / per base)	14.396 / 0.9
Data sources	HT-SELEX
Aligned words	8170

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.792	0.79	0.774	0.772	0.764	0.762
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.998	0.996	0.995	0.992

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.2
HGNC	HGNC:3114
MGI	MGI:1096341
EntrezGene (human)	GeneID:1870 (SSTAR profile)
EntrezGene (mouse)	GeneID:242705 (SSTAR profile)
UniProt ID (human)	E2F2_HUMAN
UniProt ID (mouse)	E2F2_MOUSE
UniProt AC (human)	Q14209 (TFClass)
UniProt AC (mouse)	P56931 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	E2F2.H12INVITRO.0.S.B.pcm
PWM	E2F2.H12INVITRO.0.S.B.pwm
PFM	E2F2.H12INVITRO.0.S.B.pfm
Alignment	E2F2.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	E2F2.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	E2F2.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	E2F2.H12INVITRO.0.S.B_meme_format.meme
Transfac format	E2F2.H12INVITRO.0.S.B_transfac_format.txt
Homer format	E2F2.H12INVITRO.0.S.B_homer_format_0.001.txt E2F2.H12INVITRO.0.S.B_homer_format_0.0005.txt E2F2.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1910.0	2357.0	2325.0	1578.0
02	2494.0	1375.0	3091.0	1210.0
03	3171.0	746.0	1274.0	2979.0
04	3109.0	760.0	1210.0	3091.0
05	2816.0	180.0	1043.0	4131.0
06	138.0	6.0	189.0	7837.0
07	0.0	7.0	8163.0	0.0
08	0.0	0.0	8170.0	0.0
09	1.0	8169.0	0.0	0.0
10	0.0	0.0	8170.0	0.0
11	0.0	8168.0	2.0	0.0
12	54.0	3538.0	4468.0	110.0
13	2762.0	3891.0	43.0	1474.0
14	2315.0	877.0	2765.0	2213.0
15	2020.0	3457.0	915.0	1778.0
16	1505.5	1507.5	3405.5	1751.5

PFM

	A	C	G	T
01	0.234	0.288	0.285	0.193
02	0.305	0.168	0.378	0.148
03	0.388	0.091	0.156	0.365
04	0.381	0.093	0.148	0.378
05	0.345	0.022	0.128	0.506
06	0.017	0.001	0.023	0.959
07	0.0	0.001	0.999	0.0
08	0.0	0.0	1.0	0.0
09	0.0	1.0	0.0	0.0
10	0.0	0.0	1.0	0.0
11	0.0	1.0	0.0	0.0
12	0.007	0.433	0.547	0.013
13	0.338	0.476	0.005	0.18
14	0.283	0.107	0.338	0.271
15	0.247	0.423	0.112	0.218
16	0.184	0.185	0.417	0.214

PWM

	A	C	G	T
01	-0.067	0.143	0.129	-0.258
02	0.2	-0.395	0.414	-0.523
03	0.439	-1.005	-0.471	0.377
04	0.42	-0.987	-0.523	0.414
05	0.321	-2.418	-0.671	0.704
06	-2.68	-5.513	-2.369	1.344
07	-6.811	-5.398	1.385	-6.811
08	-6.811	-6.811	1.385	-6.811
09	-6.444	1.385	-6.811	-6.811
10	-6.811	-6.811	1.385	-6.811
11	-6.811	1.385	-6.176	-6.811
12	-3.593	0.549	0.782	-2.902
13	0.301	0.644	-3.811	-0.326
14	0.125	-0.844	0.303	0.08
15	-0.011	0.526	-0.802	-0.139
16	-0.305	-0.303	0.511	-0.154

Standard thresholds

P-value	Threshold
0.001	0.81661
0.0005	2.36726
0.0001	6.39221