E2F1.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F1.H12INVIVO.0.P.B
Gene (human)	E2F1 (GeneCards)
Gene synonyms (human)	RBBP3
Gene (mouse)	E2f1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	vndSGCGGGARvn
GC content	66.14%
Information content (bits; total / per base)	10.964 / 0.843
Data sources	ChIP-Seq
Aligned words	1006

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	29 (176)	0.829	0.883	0.696	0.774	0.812	0.875	2.692	3.098	112.305	289.921
Mouse	2 (12)	0.795	0.833	0.667	0.702	0.684	0.75	2.168	2.365	39.681	90.036

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.643	0.591	0.602	0.573	0.536	0.553
Non-Methyl HT-SELEX, 3 experiments	best	0.74	0.684	0.619	0.602	0.574	0.555

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.572	2.894	0.106	0.062

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.1
HGNC	HGNC:3113
MGI	MGI:101941
EntrezGene (human)	GeneID:1869 (SSTAR profile)
EntrezGene (mouse)	GeneID:13555 (SSTAR profile)
UniProt ID (human)	E2F1_HUMAN
UniProt ID (mouse)	E2F1_MOUSE
UniProt AC (human)	Q01094 (TFClass)
UniProt AC (mouse)	Q61501 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	29 human, 2 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	E2F1.H12INVIVO.0.P.B.pcm
PWM	E2F1.H12INVIVO.0.P.B.pwm
PFM	E2F1.H12INVIVO.0.P.B.pfm
Alignment	E2F1.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	E2F1.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	E2F1.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	E2F1.H12INVIVO.0.P.B_meme_format.meme
Transfac format	E2F1.H12INVIVO.0.P.B_transfac_format.txt
Homer format	E2F1.H12INVIVO.0.P.B_homer_format_0.001.txt E2F1.H12INVIVO.0.P.B_homer_format_0.0005.txt E2F1.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	226.0	238.0	403.0	139.0
02	306.0	195.0	249.0	256.0
03	206.0	102.0	441.0	257.0
04	85.0	224.0	688.0	9.0
05	17.0	19.0	968.0	2.0
06	24.0	974.0	1.0	7.0
07	11.0	20.0	941.0	34.0
08	12.0	163.0	829.0	2.0
09	36.0	83.0	876.0	11.0
10	882.0	48.0	63.0	13.0
11	721.0	41.0	216.0	28.0
12	444.0	188.0	232.0	142.0
13	336.0	205.0	243.0	222.0

PFM

	A	C	G	T
01	0.225	0.237	0.401	0.138
02	0.304	0.194	0.248	0.254
03	0.205	0.101	0.438	0.255
04	0.084	0.223	0.684	0.009
05	0.017	0.019	0.962	0.002
06	0.024	0.968	0.001	0.007
07	0.011	0.02	0.935	0.034
08	0.012	0.162	0.824	0.002
09	0.036	0.083	0.871	0.011
10	0.877	0.048	0.063	0.013
11	0.717	0.041	0.215	0.028
12	0.441	0.187	0.231	0.141
13	0.334	0.204	0.242	0.221

PWM

	A	C	G	T
01	-0.106	-0.055	0.469	-0.587
02	0.195	-0.252	-0.01	0.018
03	-0.198	-0.893	0.559	0.021
04	-1.072	-0.115	1.002	-3.161
05	-2.604	-2.503	1.343	-4.218
06	-2.287	1.349	-4.531	-3.368
07	-2.99	-2.456	1.314	-1.958
08	-2.915	-0.43	1.188	-4.218
09	-1.904	-1.095	1.243	-2.99
10	1.25	-1.628	-1.364	-2.845
11	1.049	-1.779	-0.151	-2.142
12	0.565	-0.289	-0.08	-0.566
13	0.288	-0.203	-0.034	-0.124

Standard thresholds

P-value	Threshold
0.001	4.48206
0.0005	5.41181
0.0001	7.29747