DRGX.H12INVIVO.1.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DRGX.H12INVIVO.1.SM.D
Gene (human)	DRGX (GeneCards)
Gene synonyms (human)	PRRXL1
Gene (mouse)	Drgx
Gene synonyms (mouse)	Drg11, Prrxl1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	15
Consensus	nhdRnbYAATTAvbn
GC content	32.5%
Information content (bits; total / per base)	12.02 / 0.801
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	7101

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.985	0.976	0.973	0.959	0.934	0.905
Overall, 4 experiments	best	0.997	0.996	0.993	0.99	0.943	0.941
Methyl HT-SELEX, 1 experiments	median	0.966	0.942	0.952	0.923	0.927	0.894
Methyl HT-SELEX, 1 experiments	best	0.966	0.942	0.952	0.923	0.927	0.894
Non-Methyl HT-SELEX, 3 experiments	median	0.996	0.993	0.982	0.976	0.942	0.916
Non-Methyl HT-SELEX, 3 experiments	best	0.997	0.996	0.993	0.99	0.943	0.941

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	Paired-related HD {3.1.3} (TFClass)
TF subfamily	DRGX {3.1.3.6} (TFClass)
TFClass ID	TFClass: 3.1.3.6.1
HGNC	HGNC:21536
MGI	MGI:2148204
EntrezGene (human)	GeneID:644168 (SSTAR profile)
EntrezGene (mouse)	GeneID:107751 (SSTAR profile)
UniProt ID (human)	DRGX_HUMAN
UniProt ID (mouse)	DRGX_MOUSE
UniProt AC (human)	A6NNA5 (TFClass)
UniProt AC (mouse)	Q8BYH0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	DRGX.H12INVIVO.1.SM.D.pcm
PWM	DRGX.H12INVIVO.1.SM.D.pwm
PFM	DRGX.H12INVIVO.1.SM.D.pfm
Alignment	DRGX.H12INVIVO.1.SM.D.words.tsv
Threshold to P-value map	DRGX.H12INVIVO.1.SM.D.thr
Motif in other formats
JASPAR format	DRGX.H12INVIVO.1.SM.D_jaspar_format.txt
MEME format	DRGX.H12INVIVO.1.SM.D_meme_format.meme
Transfac format	DRGX.H12INVIVO.1.SM.D_transfac_format.txt
Homer format	DRGX.H12INVIVO.1.SM.D_homer_format_0.001.txt DRGX.H12INVIVO.1.SM.D_homer_format_0.0005.txt DRGX.H12INVIVO.1.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1924.5	1474.5	1656.5	2045.5
02	948.75	1051.75	827.75	4272.75
03	2940.0	940.0	1757.0	1464.0
04	4945.0	877.0	927.0	352.0
05	1423.0	2072.0	1200.0	2406.0
06	220.0	2651.0	1736.0	2494.0
07	301.0	2252.0	219.0	4329.0
08	5857.0	231.0	1011.0	2.0
09	7101.0	0.0	0.0	0.0
10	0.0	0.0	0.0	7101.0
11	0.0	1.0	0.0	7100.0
12	7079.0	0.0	22.0	0.0
13	2177.0	1230.0	3310.0	384.0
14	392.0	3522.0	1539.0	1648.0
15	1515.5	2035.5	2069.5	1480.5

PFM

	A	C	G	T
01	0.271	0.208	0.233	0.288
02	0.134	0.148	0.117	0.602
03	0.414	0.132	0.247	0.206
04	0.696	0.124	0.131	0.05
05	0.2	0.292	0.169	0.339
06	0.031	0.373	0.244	0.351
07	0.042	0.317	0.031	0.61
08	0.825	0.033	0.142	0.0
09	1.0	0.0	0.0	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	0.0	1.0
12	0.997	0.0	0.003	0.0
13	0.307	0.173	0.466	0.054
14	0.055	0.496	0.217	0.232
15	0.213	0.287	0.291	0.208

PWM

	A	C	G	T
01	0.081	-0.185	-0.069	0.142
02	-0.625	-0.523	-0.762	0.878
03	0.504	-0.635	-0.01	-0.193
04	1.024	-0.704	-0.649	-1.613
05	-0.221	0.154	-0.391	0.304
06	-2.079	0.401	-0.022	0.34
07	-1.768	0.238	-2.084	0.891
08	1.193	-2.031	-0.562	-6.044
09	1.385	-6.687	-6.687	-6.687
10	-6.687	-6.687	-6.687	1.385
11	-6.687	-6.314	-6.687	1.385
12	1.382	-6.687	-4.296	-6.687
13	0.204	-0.366	0.622	-1.527
14	-1.506	0.684	-0.143	-0.074
15	-0.158	0.137	0.153	-0.181

Standard thresholds

P-value	Threshold
0.001	3.82261
0.0005	5.26326
0.0001	7.51861