DRGX.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DRGX.H12INVITRO.0.S.B
Gene (human)	DRGX (GeneCards)
Gene synonyms (human)	PRRXL1
Gene (mouse)	Drgx
Gene synonyms (mouse)	Drg11, Prrxl1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	20
Consensus	nvnTAATYhRATTAvnnnnn
GC content	34.09%
Information content (bits; total / per base)	16.122 / 0.806
Data sources	HT-SELEX
Aligned words	9227

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.991	0.985	0.982	0.972	0.93	0.91
Overall, 4 experiments	best	0.999	0.998	0.998	0.997	0.944	0.943
Methyl HT-SELEX, 1 experiments	median	0.976	0.959	0.96	0.938	0.924	0.897
Methyl HT-SELEX, 1 experiments	best	0.976	0.959	0.96	0.938	0.924	0.897
Non-Methyl HT-SELEX, 3 experiments	median	0.998	0.997	0.992	0.99	0.935	0.923
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.998	0.998	0.997	0.944	0.943

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	Paired-related HD {3.1.3} (TFClass)
TF subfamily	DRGX {3.1.3.6} (TFClass)
TFClass ID	TFClass: 3.1.3.6.1
HGNC	HGNC:21536
MGI	MGI:2148204
EntrezGene (human)	GeneID:644168 (SSTAR profile)
EntrezGene (mouse)	GeneID:107751 (SSTAR profile)
UniProt ID (human)	DRGX_HUMAN
UniProt ID (mouse)	DRGX_MOUSE
UniProt AC (human)	A6NNA5 (TFClass)
UniProt AC (mouse)	Q8BYH0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	DRGX.H12INVITRO.0.S.B.pcm
PWM	DRGX.H12INVITRO.0.S.B.pwm
PFM	DRGX.H12INVITRO.0.S.B.pfm
Alignment	DRGX.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	DRGX.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	DRGX.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	DRGX.H12INVITRO.0.S.B_meme_format.meme
Transfac format	DRGX.H12INVITRO.0.S.B_transfac_format.txt
Homer format	DRGX.H12INVITRO.0.S.B_homer_format_0.001.txt DRGX.H12INVITRO.0.S.B_homer_format_0.0005.txt DRGX.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1624.0	2817.0	3027.0	1759.0
02	1476.25	2654.25	3639.25	1457.25
03	1189.0	2941.0	2808.0	2289.0
04	603.0	451.0	96.0	8077.0
05	8453.0	22.0	632.0	120.0
06	9206.0	4.0	13.0	4.0
07	109.0	506.0	105.0	8507.0
08	1.0	3048.0	434.0	5744.0
09	2859.0	1316.0	1229.0	3823.0
10	6162.0	256.0	2806.0	3.0
11	8782.0	24.0	389.0	32.0
12	1.0	8.0	2.0	9216.0
13	27.0	268.0	7.0	8925.0
14	8742.0	15.0	246.0	224.0
15	2652.0	1607.0	4495.0	473.0
16	1533.0	2829.0	2045.0	2820.0
17	1369.0	2105.0	2968.0	2785.0
18	1453.0	2793.0	3275.0	1706.0
19	1696.75	2583.75	3094.75	1851.75
20	1884.75	2457.75	2900.75	1983.75

PFM

	A	C	G	T
01	0.176	0.305	0.328	0.191
02	0.16	0.288	0.394	0.158
03	0.129	0.319	0.304	0.248
04	0.065	0.049	0.01	0.875
05	0.916	0.002	0.068	0.013
06	0.998	0.0	0.001	0.0
07	0.012	0.055	0.011	0.922
08	0.0	0.33	0.047	0.623
09	0.31	0.143	0.133	0.414
10	0.668	0.028	0.304	0.0
11	0.952	0.003	0.042	0.003
12	0.0	0.001	0.0	0.999
13	0.003	0.029	0.001	0.967
14	0.947	0.002	0.027	0.024
15	0.287	0.174	0.487	0.051
16	0.166	0.307	0.222	0.306
17	0.148	0.228	0.322	0.302
18	0.157	0.303	0.355	0.185
19	0.184	0.28	0.335	0.201
20	0.204	0.266	0.314	0.215

PWM

	A	C	G	T
01	-0.351	0.2	0.271	-0.271
02	-0.446	0.14	0.456	-0.459
03	-0.662	0.243	0.196	-0.008
04	-1.339	-1.628	-3.157	1.252
05	1.298	-4.555	-1.292	-2.938
06	1.383	-5.907	-5.018	-5.907
07	-3.033	-1.514	-3.069	1.304
08	-6.556	0.278	-1.666	0.912
09	0.214	-0.56	-0.629	0.505
10	0.982	-2.191	0.196	-6.08
11	1.336	-4.476	-1.775	-4.21
12	-6.556	-5.414	-6.29	1.384
13	-4.368	-2.145	-5.516	1.352
14	1.332	-4.895	-2.23	-2.323
15	0.139	-0.361	0.667	-1.581
16	-0.408	0.204	-0.12	0.201
17	-0.521	-0.091	0.252	0.188
18	-0.462	0.191	0.35	-0.301
19	-0.307	0.113	0.294	-0.219
20	-0.202	0.063	0.229	-0.151

Standard thresholds

P-value	Threshold
0.001	1.39671
0.0005	2.88046
0.0001	5.93431