DPRX.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DPRX.H12CORE.0.SM.B
Gene (human)	DPRX (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nvGGATTAdbnn
GC content	45.58%
Information content (bits; total / per base)	12.753 / 1.063
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8868

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.995	0.993	0.99	0.968	0.962
Overall, 4 experiments	best	0.998	0.996	0.996	0.993	0.984	0.978
Methyl HT-SELEX, 1 experiments	median	0.998	0.996	0.996	0.993	0.984	0.978
Methyl HT-SELEX, 1 experiments	best	0.998	0.996	0.996	0.993	0.984	0.978
Non-Methyl HT-SELEX, 3 experiments	median	0.997	0.994	0.992	0.988	0.953	0.947
Non-Methyl HT-SELEX, 3 experiments	best	0.998	0.996	0.995	0.993	0.983	0.977

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	Paired-related HD {3.1.3} (TFClass)
TF subfamily	DPRX {3.1.3.5} (TFClass)
TFClass ID	TFClass: 3.1.3.5.1
HGNC	HGNC:32166
MGI
EntrezGene (human)	GeneID:503834 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	DPRX_HUMAN
UniProt ID (mouse)
UniProt AC (human)	A6NFQ7 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	DPRX.H12CORE.0.SM.B.pcm
PWM	DPRX.H12CORE.0.SM.B.pwm
PFM	DPRX.H12CORE.0.SM.B.pfm
Alignment	DPRX.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	DPRX.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	DPRX.H12CORE.0.SM.B_jaspar_format.txt
MEME format	DPRX.H12CORE.0.SM.B_meme_format.meme
Transfac format	DPRX.H12CORE.0.SM.B_transfac_format.txt
Homer format	DPRX.H12CORE.0.SM.B_homer_format_0.001.txt DPRX.H12CORE.0.SM.B_homer_format_0.0005.txt DPRX.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2564.0	2097.0	2602.0	1605.0
02	1639.0	3421.0	2458.0	1350.0
03	2.0	0.0	8866.0	0.0
04	0.0	0.0	8868.0	0.0
05	8868.0	0.0	0.0	0.0
06	0.0	0.0	0.0	8868.0
07	0.0	0.0	0.0	8868.0
08	8868.0	0.0	0.0	0.0
09	2879.0	464.0	2761.0	2764.0
10	559.0	4939.0	1729.0	1641.0
11	1705.5	3330.5	2080.5	1751.5
12	1916.5	2459.5	2432.5	2059.5

PFM

	A	C	G	T
01	0.289	0.236	0.293	0.181
02	0.185	0.386	0.277	0.152
03	0.0	0.0	1.0	0.0
04	0.0	0.0	1.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	0.0	1.0
08	1.0	0.0	0.0	0.0
09	0.325	0.052	0.311	0.312
10	0.063	0.557	0.195	0.185
11	0.192	0.376	0.235	0.198
12	0.216	0.277	0.274	0.232

PWM

	A	C	G	T
01	0.145	-0.056	0.16	-0.323
02	-0.302	0.433	0.103	-0.495
03	-6.253	-6.884	1.385	-6.884
04	-6.884	-6.884	1.386	-6.884
05	1.386	-6.884	-6.884	-6.884
06	-6.884	-6.884	-6.884	1.386
07	-6.884	-6.884	-6.884	1.386
08	1.386	-6.884	-6.884	-6.884
09	0.261	-1.56	0.219	0.22
10	-1.375	0.8	-0.248	-0.3
11	-0.262	0.407	-0.063	-0.235
12	-0.145	0.104	0.093	-0.074

Standard thresholds

P-value	Threshold
0.001	0.615265
0.0005	1.25032
0.0001	8.02542