DMTA2.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMTA2.H12CORE.0.SM.B
Gene (human)	DMRTA2 (GeneCards)
Gene synonyms (human)	DMRT5
Gene (mouse)	Dmrta2
Gene synonyms (mouse)	Dmrt5
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	nhhRhTGTAWCddhhn
GC content	35.32%
Information content (bits; total / per base)	11.955 / 0.747
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9246

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.987	0.977	0.974	0.961	0.939	0.921
Overall, 2 experiments	best	0.987	0.979	0.975	0.961	0.946	0.927
Methyl HT-SELEX, 1 experiments	median	0.986	0.976	0.975	0.961	0.946	0.927
Methyl HT-SELEX, 1 experiments	best	0.986	0.976	0.975	0.961	0.946	0.927
Non-Methyl HT-SELEX, 1 experiments	median	0.987	0.979	0.973	0.96	0.933	0.915
Non-Methyl HT-SELEX, 1 experiments	best	0.987	0.979	0.973	0.96	0.933	0.915

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.5
HGNC	HGNC:13908
MGI	MGI:2653629
EntrezGene (human)	GeneID:63950 (SSTAR profile)
EntrezGene (mouse)	GeneID:242620 (SSTAR profile)
UniProt ID (human)	DMTA2_HUMAN
UniProt ID (mouse)	DMTA2_MOUSE
UniProt AC (human)	Q96SC8 (TFClass)
UniProt AC (mouse)	A2A9A2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	DMTA2.H12CORE.0.SM.B.pcm
PWM	DMTA2.H12CORE.0.SM.B.pwm
PFM	DMTA2.H12CORE.0.SM.B.pfm
Alignment	DMTA2.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	DMTA2.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	DMTA2.H12CORE.0.SM.B_jaspar_format.txt
MEME format	DMTA2.H12CORE.0.SM.B_meme_format.meme
Transfac format	DMTA2.H12CORE.0.SM.B_transfac_format.txt
Homer format	DMTA2.H12CORE.0.SM.B_homer_format_0.001.txt DMTA2.H12CORE.0.SM.B_homer_format_0.0005.txt DMTA2.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2508.75	1657.75	2870.75	2208.75
02	4258.5	1830.5	1435.5	1721.5
03	2488.0	4129.0	1036.0	1593.0
04	7384.0	653.0	677.0	532.0
05	4708.0	1822.0	300.0	2416.0
06	594.0	8.0	9.0	8635.0
07	0.0	0.0	9246.0	0.0
08	0.0	0.0	0.0	9246.0
09	7349.0	20.0	18.0	1859.0
10	4293.0	8.0	1786.0	3159.0
11	18.0	9131.0	56.0	41.0
12	5065.0	972.0	2163.0	1046.0
13	4718.0	978.0	1291.0	2259.0
14	1852.0	1762.0	1108.0	4524.0
15	2015.75	1622.75	1422.75	4184.75
16	1616.5	2203.5	2041.5	3384.5

PFM

	A	C	G	T
01	0.271	0.179	0.31	0.239
02	0.461	0.198	0.155	0.186
03	0.269	0.447	0.112	0.172
04	0.799	0.071	0.073	0.058
05	0.509	0.197	0.032	0.261
06	0.064	0.001	0.001	0.934
07	0.0	0.0	1.0	0.0
08	0.0	0.0	0.0	1.0
09	0.795	0.002	0.002	0.201
10	0.464	0.001	0.193	0.342
11	0.002	0.988	0.006	0.004
12	0.548	0.105	0.234	0.113
13	0.51	0.106	0.14	0.244
14	0.2	0.191	0.12	0.489
15	0.218	0.176	0.154	0.453
16	0.175	0.238	0.221	0.366

PWM

	A	C	G	T
01	0.082	-0.332	0.216	-0.045
02	0.611	-0.233	-0.476	-0.294
03	0.074	0.58	-0.801	-0.372
04	1.161	-1.262	-1.226	-1.466
05	0.711	-0.238	-2.035	0.044
06	-1.356	-5.416	-5.323	1.317
07	-6.921	-6.921	1.386	-6.921
08	-6.921	-6.921	-6.921	1.386
09	1.156	-4.643	-4.737	-0.218
10	0.619	-5.416	-0.258	0.312
11	-4.737	1.373	-3.681	-3.979
12	0.784	-0.865	-0.066	-0.792
13	0.713	-0.859	-0.582	-0.023
14	-0.221	-0.271	-0.734	0.671
15	-0.137	-0.353	-0.485	0.593
16	-0.357	-0.048	-0.124	0.381

Standard thresholds

P-value	Threshold
0.001	3.98186
0.0005	5.26496
0.0001	7.45571