DMRTD.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMRTD.H12INVIVO.0.SM.D
Gene (human)	DMRTC2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dmrtc2
Gene synonyms (mouse)	Dmrt7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	14
Consensus	nvdWWYGMTACAWb
GC content	32.1%
Information content (bits; total / per base)	13.541 / 0.967
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	7329

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.986	0.982	0.943	0.93	0.841	0.835
Overall, 4 experiments	best	0.995	0.993	0.953	0.945	0.852	0.84
Methyl HT-SELEX, 2 experiments	median	0.99	0.988	0.921	0.913	0.79	0.796
Methyl HT-SELEX, 2 experiments	best	0.995	0.993	0.953	0.945	0.837	0.836
Non-Methyl HT-SELEX, 2 experiments	median	0.986	0.982	0.943	0.93	0.848	0.837
Non-Methyl HT-SELEX, 2 experiments	best	0.987	0.983	0.946	0.932	0.852	0.84

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.7
HGNC	HGNC:13911
MGI	MGI:1918491
EntrezGene (human)	GeneID:63946 (SSTAR profile)
EntrezGene (mouse)	GeneID:71241 (SSTAR profile)
UniProt ID (human)	DMRTD_HUMAN
UniProt ID (mouse)	DMRTD_MOUSE
UniProt AC (human)	Q8IXT2 (TFClass)
UniProt AC (mouse)	Q8CGW9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	DMRTD.H12INVIVO.0.SM.D.pcm
PWM	DMRTD.H12INVIVO.0.SM.D.pwm
PFM	DMRTD.H12INVIVO.0.SM.D.pfm
Alignment	DMRTD.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	DMRTD.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	DMRTD.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	DMRTD.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	DMRTD.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	DMRTD.H12INVIVO.0.SM.D_homer_format_0.001.txt DMRTD.H12INVIVO.0.SM.D_homer_format_0.0005.txt DMRTD.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2123.0	1990.0	1608.0	1608.0
02	3711.0	1349.0	1270.0	999.0
03	4098.0	939.0	978.0	1314.0
04	4542.0	602.0	701.0	1484.0
05	1336.0	398.0	356.0	5239.0
06	120.0	1215.0	369.0	5625.0
07	0.0	7.0	7318.0	4.0
08	4883.0	1740.0	1.0	705.0
09	117.0	94.0	30.0	7088.0
10	7328.0	1.0	0.0	0.0
11	1.0	7328.0	0.0	0.0
12	7002.0	46.0	95.0	186.0
13	1199.25	954.25	687.25	4488.25
14	1154.25	1608.25	1247.25	3319.25

PFM

	A	C	G	T
01	0.29	0.272	0.219	0.219
02	0.506	0.184	0.173	0.136
03	0.559	0.128	0.133	0.179
04	0.62	0.082	0.096	0.202
05	0.182	0.054	0.049	0.715
06	0.016	0.166	0.05	0.767
07	0.0	0.001	0.998	0.001
08	0.666	0.237	0.0	0.096
09	0.016	0.013	0.004	0.967
10	1.0	0.0	0.0	0.0
11	0.0	1.0	0.0	0.0
12	0.955	0.006	0.013	0.025
13	0.164	0.13	0.094	0.612
14	0.157	0.219	0.17	0.453

PWM

	A	C	G	T
01	0.147	0.082	-0.13	-0.13
02	0.705	-0.306	-0.366	-0.606
03	0.804	-0.667	-0.627	-0.332
04	0.907	-1.111	-0.959	-0.211
05	-0.315	-1.522	-1.633	1.05
06	-2.709	-0.41	-1.598	1.121
07	-6.715	-5.293	1.384	-5.686
08	0.979	-0.052	-6.344	-0.953
09	-2.734	-2.948	-4.042	1.352
10	1.385	-6.344	-6.715	-6.715
11	-6.344	1.385	-6.715	-6.715
12	1.34	-3.639	-2.937	-2.277
13	-0.423	-0.651	-0.979	0.895
14	-0.461	-0.13	-0.384	0.594

Standard thresholds

P-value	Threshold
0.001	3.01221
0.0005	4.39781
0.0001	7.06891