DMRTA.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMRTA.H12CORE.0.SM.B
Gene (human)	DMRTA1 (GeneCards)
Gene synonyms (human)	DMO
Gene (mouse)	Dmrta1
Gene synonyms (mouse)	Dmrt4
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	nhAWTGTAWCRWWdbn
GC content	31.34%
Information content (bits; total / per base)	13.999 / 0.875
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9637

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.997	0.996	0.989	0.985	0.917	0.915
Overall, 2 experiments	best	0.998	0.997	0.993	0.991	0.917	0.92
Methyl HT-SELEX, 1 experiments	median	0.998	0.997	0.993	0.991	0.917	0.92
Methyl HT-SELEX, 1 experiments	best	0.998	0.997	0.993	0.991	0.917	0.92
Non-Methyl HT-SELEX, 1 experiments	median	0.996	0.994	0.984	0.978	0.917	0.911
Non-Methyl HT-SELEX, 1 experiments	best	0.996	0.994	0.984	0.978	0.917	0.911

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.4
HGNC	HGNC:13826
MGI	MGI:2653627
EntrezGene (human)	GeneID:63951 (SSTAR profile)
EntrezGene (mouse)	GeneID:242523 (SSTAR profile)
UniProt ID (human)	DMRTA_HUMAN
UniProt ID (mouse)	DMRTA_MOUSE
UniProt AC (human)	Q5VZB9 (TFClass)
UniProt AC (mouse)	Q8CFG4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	DMRTA.H12CORE.0.SM.B.pcm
PWM	DMRTA.H12CORE.0.SM.B.pwm
PFM	DMRTA.H12CORE.0.SM.B.pfm
Alignment	DMRTA.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	DMRTA.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	DMRTA.H12CORE.0.SM.B_jaspar_format.txt
MEME format	DMRTA.H12CORE.0.SM.B_meme_format.meme
Transfac format	DMRTA.H12CORE.0.SM.B_transfac_format.txt
Homer format	DMRTA.H12CORE.0.SM.B_homer_format_0.001.txt DMRTA.H12CORE.0.SM.B_homer_format_0.0005.txt DMRTA.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3595.25	2252.25	1637.25	2152.25
02	3429.0	3230.0	1191.0	1787.0
03	7994.0	522.0	600.0	521.0
04	5807.0	1769.0	209.0	1852.0
05	611.0	39.0	2.0	8985.0
06	1.0	0.0	9635.0	1.0
07	1.0	0.0	0.0	9636.0
08	7920.0	1.0	9.0	1707.0
09	5899.0	3.0	1382.0	2353.0
10	10.0	9615.0	8.0	4.0
11	7697.0	408.0	1119.0	413.0
12	6751.0	533.0	951.0	1402.0
13	2028.0	1233.0	656.0	5720.0
14	1822.0	1181.0	1248.0	5386.0
15	1173.75	1945.75	1787.75	4729.75
16	1920.0	2447.0	2708.0	2562.0

PFM

	A	C	G	T
01	0.373	0.234	0.17	0.223
02	0.356	0.335	0.124	0.185
03	0.83	0.054	0.062	0.054
04	0.603	0.184	0.022	0.192
05	0.063	0.004	0.0	0.932
06	0.0	0.0	1.0	0.0
07	0.0	0.0	0.0	1.0
08	0.822	0.0	0.001	0.177
09	0.612	0.0	0.143	0.244
10	0.001	0.998	0.001	0.0
11	0.799	0.042	0.116	0.043
12	0.701	0.055	0.099	0.145
13	0.21	0.128	0.068	0.594
14	0.189	0.123	0.13	0.559
15	0.122	0.202	0.186	0.491
16	0.199	0.254	0.281	0.266

PWM

	A	C	G	T
01	0.4	-0.067	-0.386	-0.113
02	0.353	0.293	-0.704	-0.298
03	1.199	-1.526	-1.387	-1.528
04	0.879	-0.309	-2.435	-0.263
05	-1.369	-4.067	-6.331	1.316
06	-6.596	-6.958	1.385	-6.596
07	-6.596	-6.958	-6.958	1.385
08	1.189	-6.596	-5.364	-0.344
09	0.895	-6.122	-0.555	-0.024
10	-5.279	1.383	-5.457	-5.949
11	1.161	-1.771	-0.766	-1.759
12	1.03	-1.505	-0.928	-0.541
13	-0.172	-0.669	-1.298	0.864
14	-0.279	-0.712	-0.657	0.804
15	-0.718	-0.213	-0.298	0.674
16	-0.227	0.016	0.117	0.061

Standard thresholds

P-value	Threshold
0.001	2.78131
0.0005	4.27101
0.0001	6.94981