DMRT1.H12INVITRO.1.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMRT1.H12INVITRO.1.M.C
Gene (human)	DMRT1 (GeneCards)
Gene synonyms (human)	DMT1
Gene (mouse)	Dmrt1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	12
Consensus	nhYGYTACRWYn
GC content	42.79%
Information content (bits; total / per base)	10.177 / 0.848
Data sources	Methyl-HT-SELEX
Aligned words	1703

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.902	0.908	0.839	0.846	0.841	0.847	2.895	2.916	219.523	242.102

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.96	0.939	0.926	0.903	0.871	0.852
Overall, 2 experiments	best	0.992	0.985	0.986	0.977	0.969	0.956
Methyl HT-SELEX, 1 experiments	median	0.928	0.893	0.867	0.828	0.773	0.748
Methyl HT-SELEX, 1 experiments	best	0.928	0.893	0.867	0.828	0.773	0.748
Non-Methyl HT-SELEX, 1 experiments	median	0.992	0.985	0.986	0.977	0.969	0.956
Non-Methyl HT-SELEX, 1 experiments	best	0.992	0.985	0.986	0.977	0.969	0.956

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.1
HGNC	HGNC:2934
MGI	MGI:1354733
EntrezGene (human)	GeneID:1761 (SSTAR profile)
EntrezGene (mouse)	GeneID:50796 (SSTAR profile)
UniProt ID (human)	DMRT1_HUMAN
UniProt ID (mouse)	DMRT1_MOUSE
UniProt AC (human)	Q9Y5R6 (TFClass)
UniProt AC (mouse)	Q9QZ59 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	DMRT1.H12INVITRO.1.M.C.pcm
PWM	DMRT1.H12INVITRO.1.M.C.pwm
PFM	DMRT1.H12INVITRO.1.M.C.pfm
Alignment	DMRT1.H12INVITRO.1.M.C.words.tsv
Threshold to P-value map	DMRT1.H12INVITRO.1.M.C.thr
Motif in other formats
JASPAR format	DMRT1.H12INVITRO.1.M.C_jaspar_format.txt
MEME format	DMRT1.H12INVITRO.1.M.C_meme_format.meme
Transfac format	DMRT1.H12INVITRO.1.M.C_transfac_format.txt
Homer format	DMRT1.H12INVITRO.1.M.C_homer_format_0.001.txt DMRT1.H12INVITRO.1.M.C_homer_format_0.0005.txt DMRT1.H12INVITRO.1.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	548.0	471.0	265.0	419.0
02	490.25	213.25	175.25	824.25
03	69.0	1109.0	118.0	407.0
04	4.0	165.0	1533.0	1.0
05	364.0	958.0	0.0	381.0
06	591.0	5.0	0.0	1107.0
07	1700.0	3.0	0.0	0.0
08	0.0	1703.0	0.0	0.0
09	1319.0	117.0	251.0	16.0
10	532.0	132.0	18.0	1021.0
11	137.25	372.25	182.25	1011.25
12	412.75	417.75	535.75	336.75

PFM

	A	C	G	T
01	0.322	0.277	0.156	0.246
02	0.288	0.125	0.103	0.484
03	0.041	0.651	0.069	0.239
04	0.002	0.097	0.9	0.001
05	0.214	0.563	0.0	0.224
06	0.347	0.003	0.0	0.65
07	0.998	0.002	0.0	0.0
08	0.0	1.0	0.0	0.0
09	0.775	0.069	0.147	0.009
10	0.312	0.078	0.011	0.6
11	0.081	0.219	0.107	0.594
12	0.242	0.245	0.315	0.198

PWM

	A	C	G	T
01	0.251	0.101	-0.471	-0.016
02	0.14	-0.687	-0.881	0.659
03	-1.798	0.955	-1.272	-0.045
04	-4.29	-0.941	1.278	-5.007
05	-0.156	0.809	-5.438	-0.111
06	0.327	-4.132	-5.438	0.953
07	1.381	-4.477	-5.438	-5.438
08	-5.438	1.383	-5.438	-5.438
09	1.128	-1.28	-0.525	-3.176
10	0.222	-1.161	-3.07	0.872
11	-1.123	-0.134	-0.843	0.863
12	-0.031	-0.019	0.229	-0.233

Standard thresholds

P-value	Threshold
0.001	4.92092
0.0005	5.84027
0.0001	7.469575