DMRT1.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMRT1.H12INVITRO.0.PS.A
Gene (human)	DMRT1 (GeneCards)
Gene synonyms (human)	DMT1
Gene (mouse)	Dmrt1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	nhdWbGMTACAWYbbn
GC content	36.4%
Information content (bits; total / per base)	12.503 / 0.781
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9976

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.948	0.952	0.899	0.908	0.936	0.939	4.133	4.163	305.377	328.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.947	0.927	0.899	0.881	0.841	0.833
Overall, 2 experiments	best	0.997	0.995	0.995	0.992	0.987	0.982
Methyl HT-SELEX, 1 experiments	median	0.896	0.858	0.803	0.769	0.695	0.685
Methyl HT-SELEX, 1 experiments	best	0.896	0.858	0.803	0.769	0.695	0.685
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.995	0.992	0.987	0.982
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.995	0.992	0.987	0.982

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.1
HGNC	HGNC:2934
MGI	MGI:1354733
EntrezGene (human)	GeneID:1761 (SSTAR profile)
EntrezGene (mouse)	GeneID:50796 (SSTAR profile)
UniProt ID (human)	DMRT1_HUMAN
UniProt ID (mouse)	DMRT1_MOUSE
UniProt AC (human)	Q9Y5R6 (TFClass)
UniProt AC (mouse)	Q9QZ59 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	DMRT1.H12INVITRO.0.PS.A.pcm
PWM	DMRT1.H12INVITRO.0.PS.A.pwm
PFM	DMRT1.H12INVITRO.0.PS.A.pfm
Alignment	DMRT1.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	DMRT1.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	DMRT1.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	DMRT1.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	DMRT1.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	DMRT1.H12INVITRO.0.PS.A_homer_format_0.001.txt DMRT1.H12INVITRO.0.PS.A_homer_format_0.0005.txt DMRT1.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3695.75	2240.75	2386.75	1652.75
02	4477.5	1757.5	1670.5	2070.5
03	4611.0	1133.0	1895.0	2337.0
04	1446.0	1080.0	839.0	6611.0
05	764.0	3124.0	1319.0	4769.0
06	69.0	45.0	9835.0	27.0
07	4500.0	3141.0	14.0	2321.0
08	2263.0	15.0	7.0	7691.0
09	9967.0	3.0	5.0	1.0
10	2.0	9966.0	4.0	4.0
11	9661.0	30.0	37.0	248.0
12	2401.0	280.0	254.0	7041.0
13	710.0	1375.0	736.0	7155.0
14	1176.0	1604.0	5152.0	2044.0
15	1512.75	2165.75	1849.75	4447.75
16	2826.0	2124.0	2011.0	3015.0

PFM

	A	C	G	T
01	0.37	0.225	0.239	0.166
02	0.449	0.176	0.167	0.208
03	0.462	0.114	0.19	0.234
04	0.145	0.108	0.084	0.663
05	0.077	0.313	0.132	0.478
06	0.007	0.005	0.986	0.003
07	0.451	0.315	0.001	0.233
08	0.227	0.002	0.001	0.771
09	0.999	0.0	0.001	0.0
10	0.0	0.999	0.0	0.0
11	0.968	0.003	0.004	0.025
12	0.241	0.028	0.025	0.706
13	0.071	0.138	0.074	0.717
14	0.118	0.161	0.516	0.205
15	0.152	0.217	0.185	0.446
16	0.283	0.213	0.202	0.302

PWM

	A	C	G	T
01	0.393	-0.107	-0.044	-0.411
02	0.585	-0.35	-0.4	-0.186
03	0.614	-0.788	-0.274	-0.065
04	-0.544	-0.836	-1.088	0.974
05	-1.181	0.225	-0.636	0.648
06	-3.556	-3.966	1.371	-4.445
07	0.59	0.23	-5.031	-0.072
08	-0.097	-4.972	-5.592	1.126
09	1.385	-6.154	-5.834	-6.628
10	-6.363	1.385	-5.982	-5.982
11	1.354	-4.347	-4.151	-2.3
12	-0.038	-2.18	-2.276	1.037
13	-1.254	-0.595	-1.218	1.053
14	-0.751	-0.441	0.725	-0.199
15	-0.499	-0.141	-0.299	0.578
16	0.125	-0.16	-0.215	0.19

Standard thresholds

P-value	Threshold
0.001	3.57911
0.0005	4.94276
0.0001	7.36031