DMRT1.H12CORE.1.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMRT1.H12CORE.1.M.C
Gene (human)	DMRT1 (GeneCards)
Gene synonyms (human)	DMT1
Gene (mouse)	Dmrt1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	13
Consensus	nhhYGYWACAWYn
GC content	42.7%
Information content (bits; total / per base)	10.479 / 0.806
Data sources	Methyl-HT-SELEX
Aligned words	718

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.902	0.908	0.835	0.842	0.849	0.854	2.95	2.969	223.62	243.149

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.958	0.936	0.926	0.901	0.874	0.853
Overall, 2 experiments	best	0.99	0.982	0.985	0.975	0.967	0.954
Methyl HT-SELEX, 1 experiments	median	0.926	0.89	0.867	0.827	0.781	0.752
Methyl HT-SELEX, 1 experiments	best	0.926	0.89	0.867	0.827	0.781	0.752
Non-Methyl HT-SELEX, 1 experiments	median	0.99	0.982	0.985	0.975	0.967	0.954
Non-Methyl HT-SELEX, 1 experiments	best	0.99	0.982	0.985	0.975	0.967	0.954

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.1
HGNC	HGNC:2934
MGI	MGI:1354733
EntrezGene (human)	GeneID:1761 (SSTAR profile)
EntrezGene (mouse)	GeneID:50796 (SSTAR profile)
UniProt ID (human)	DMRT1_HUMAN
UniProt ID (mouse)	DMRT1_MOUSE
UniProt AC (human)	Q9Y5R6 (TFClass)
UniProt AC (mouse)	Q9QZ59 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	DMRT1.H12CORE.1.M.C.pcm
PWM	DMRT1.H12CORE.1.M.C.pwm
PFM	DMRT1.H12CORE.1.M.C.pfm
Alignment	DMRT1.H12CORE.1.M.C.words.tsv
Threshold to P-value map	DMRT1.H12CORE.1.M.C.thr
Motif in other formats
JASPAR format	DMRT1.H12CORE.1.M.C_jaspar_format.txt
MEME format	DMRT1.H12CORE.1.M.C_meme_format.meme
Transfac format	DMRT1.H12CORE.1.M.C_transfac_format.txt
Homer format	DMRT1.H12CORE.1.M.C_homer_format_0.001.txt DMRT1.H12CORE.1.M.C_homer_format_0.0005.txt DMRT1.H12CORE.1.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	150.25	268.25	117.25	182.25
02	264.0	210.0	72.0	172.0
03	223.0	82.0	48.0	365.0
04	22.0	475.0	64.0	157.0
05	4.0	56.0	657.0	1.0
06	164.0	379.0	2.0	173.0
07	264.0	3.0	2.0	449.0
08	716.0	2.0	0.0	0.0
09	0.0	718.0	0.0	0.0
10	568.0	34.0	106.0	10.0
11	211.0	66.0	3.0	438.0
12	54.75	158.75	61.75	442.75
13	162.5	161.5	239.5	154.5

PFM

	A	C	G	T
01	0.209	0.374	0.163	0.254
02	0.368	0.292	0.1	0.24
03	0.311	0.114	0.067	0.508
04	0.031	0.662	0.089	0.219
05	0.006	0.078	0.915	0.001
06	0.228	0.528	0.003	0.241
07	0.368	0.004	0.003	0.625
08	0.997	0.003	0.0	0.0
09	0.0	1.0	0.0	0.0
10	0.791	0.047	0.148	0.014
11	0.294	0.092	0.004	0.61
12	0.076	0.221	0.086	0.617
13	0.226	0.225	0.334	0.215

PWM

	A	C	G	T
01	-0.176	0.399	-0.421	0.015
02	0.383	0.156	-0.9	-0.042
03	0.215	-0.773	-1.294	0.705
04	-2.036	0.967	-1.015	-0.133
05	-3.469	-1.145	1.291	-4.227
06	-0.089	0.743	-3.906	-0.037
07	0.383	-3.664	-3.906	0.911
08	1.377	-3.906	-4.702	-4.702
09	-4.702	1.379	-4.702	-4.702
10	1.146	-1.626	-0.52	-2.744
11	0.16	-0.985	-3.664	0.887
12	-1.167	-0.122	-1.05	0.897
13	-0.099	-0.105	0.286	-0.149

Standard thresholds

P-value	Threshold
0.001	4.77246
0.0005	5.72546
0.0001	7.46152