DMRT1.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DMRT1.H12CORE.0.PS.A
Gene (human)	DMRT1 (GeneCards)
Gene synonyms (human)	DMT1
Gene (mouse)	Dmrt1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	nhKGYWACAhTGTddY
GC content	39.83%
Information content (bits; total / per base)	14.163 / 0.885
Data sources	ChIP-Seq + HT-SELEX
Aligned words	803

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.97	0.975	0.952	0.962	0.971	0.974	6.149	6.282	407.108	423.076

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.885	0.863	0.827	0.809	0.764	0.753
Overall, 2 experiments	best	0.993	0.989	0.971	0.961	0.919	0.903
Methyl HT-SELEX, 1 experiments	median	0.777	0.737	0.683	0.657	0.608	0.603
Methyl HT-SELEX, 1 experiments	best	0.777	0.737	0.683	0.657	0.608	0.603
Non-Methyl HT-SELEX, 1 experiments	median	0.993	0.989	0.971	0.961	0.919	0.903
Non-Methyl HT-SELEX, 1 experiments	best	0.993	0.989	0.971	0.961	0.919	0.903

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	DM-type intertwined zinc finger factors {2.5} (TFClass)
TF family	DMRT {2.5.1} (TFClass)
TF subfamily	{2.5.1.0} (TFClass)
TFClass ID	TFClass: 2.5.1.0.1
HGNC	HGNC:2934
MGI	MGI:1354733
EntrezGene (human)	GeneID:1761 (SSTAR profile)
EntrezGene (mouse)	GeneID:50796 (SSTAR profile)
UniProt ID (human)	DMRT1_HUMAN
UniProt ID (mouse)	DMRT1_MOUSE
UniProt AC (human)	Q9Y5R6 (TFClass)
UniProt AC (mouse)	Q9QZ59 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	DMRT1.H12CORE.0.PS.A.pcm
PWM	DMRT1.H12CORE.0.PS.A.pwm
PFM	DMRT1.H12CORE.0.PS.A.pfm
Alignment	DMRT1.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	DMRT1.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	DMRT1.H12CORE.0.PS.A_jaspar_format.txt
MEME format	DMRT1.H12CORE.0.PS.A_meme_format.meme
Transfac format	DMRT1.H12CORE.0.PS.A_transfac_format.txt
Homer format	DMRT1.H12CORE.0.PS.A_homer_format_0.001.txt DMRT1.H12CORE.0.PS.A_homer_format_0.0005.txt DMRT1.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	247.0	145.0	167.0	244.0
02	89.0	207.0	78.0	429.0
03	156.0	8.0	183.0	456.0
04	5.0	8.0	781.0	9.0
05	170.0	385.0	4.0	244.0
06	247.0	78.0	23.0	455.0
07	770.0	1.0	21.0	11.0
08	5.0	761.0	15.0	22.0
09	581.0	15.0	4.0	203.0
10	220.0	90.0	83.0	410.0
11	74.0	5.0	16.0	708.0
12	11.0	16.0	741.0	35.0
13	13.0	19.0	13.0	758.0
14	324.0	95.0	112.0	272.0
15	119.0	73.0	278.0	333.0
16	46.0	644.0	48.0	65.0

PFM

	A	C	G	T
01	0.308	0.181	0.208	0.304
02	0.111	0.258	0.097	0.534
03	0.194	0.01	0.228	0.568
04	0.006	0.01	0.973	0.011
05	0.212	0.479	0.005	0.304
06	0.308	0.097	0.029	0.567
07	0.959	0.001	0.026	0.014
08	0.006	0.948	0.019	0.027
09	0.724	0.019	0.005	0.253
10	0.274	0.112	0.103	0.511
11	0.092	0.006	0.02	0.882
12	0.014	0.02	0.923	0.044
13	0.016	0.024	0.016	0.944
14	0.403	0.118	0.139	0.339
15	0.148	0.091	0.346	0.415
16	0.057	0.802	0.06	0.081

PWM

	A	C	G	T
01	0.206	-0.322	-0.182	0.194
02	-0.803	0.03	-0.932	0.755
03	-0.25	-3.041	-0.092	0.816
04	-3.412	-3.041	1.352	-2.943
05	-0.165	0.647	-3.575	0.194
06	0.206	-0.932	-2.105	0.814
07	1.338	-4.327	-2.189	-2.771
08	-3.412	1.326	-2.497	-2.146
09	1.057	-2.497	-3.575	0.011
10	0.091	-0.792	-0.872	0.71
11	-0.984	-3.412	-2.438	1.254
12	-2.771	-2.438	1.3	-1.708
13	-2.624	-2.282	-2.624	1.323
14	0.476	-0.739	-0.577	0.302
15	-0.517	-0.997	0.323	0.503
16	-1.446	1.16	-1.405	-1.111

Standard thresholds

P-value	Threshold
0.001	3.37986
0.0005	4.47886
0.0001	6.78586