MotifDMBX1.H12CORE.0.SM.B
Gene (human)DMBX1
(GeneCards)
Gene synonyms (human)MBX, OTX3, PAXB
Gene (mouse)Dmbx1
Gene synonyms (mouse)Cdmx, Mbx, Otx3, PaxB
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusnbSATTAvn
GC content40.65%
Information content (bits; total / per base)7.59 / 0.843
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8418

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.907 0.857 0.864 0.812 0.787 0.749
best 0.984 0.973 0.973 0.958 0.934 0.915
Methyl HT-SELEX, 2 experiments median 0.95 0.923 0.92 0.889 0.858 0.832
best 0.984 0.973 0.973 0.958 0.934 0.915
Non-Methyl HT-SELEX, 4 experiments median 0.811 0.765 0.742 0.708 0.676 0.657
best 0.937 0.897 0.908 0.864 0.845 0.806

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.58 0.128 0.488 0.297
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyDMBX {3.1.3.4} (TFClass)
TFClass IDTFClass: 3.1.3.4.1
HGNCHGNC:19026
MGIMGI:2153518
EntrezGene (human)GeneID:127343
(SSTAR profile)
EntrezGene (mouse)GeneID:140477
(SSTAR profile)
UniProt ID (human)DMBX1_HUMAN
UniProt ID (mouse)DMBX1_MOUSE
UniProt AC (human)Q8NFW5
(TFClass)
UniProt AC (mouse)Q91ZK4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
011943.252495.252418.251561.25
021216.751970.753784.751445.75
03328.01461.06474.0155.0
046721.01428.0268.01.0
050.01.00.08417.0
0610.0463.00.07945.0
077633.0511.060.0214.0
083188.51677.52503.51048.5
091341.252872.252407.251797.25
PFM
ACGT
010.2310.2960.2870.185
020.1450.2340.450.172
030.0390.1740.7690.018
040.7980.170.0320.0
050.00.00.01.0
060.0010.0550.00.944
070.9070.0610.0070.025
080.3790.1990.2970.125
090.1590.3410.2860.214
PWM
ACGT
01-0.080.170.139-0.298
02-0.547-0.0660.586-0.375
03-1.853-0.3641.123-2.595
041.16-0.387-2.054-6.471
05-6.838-6.471-6.8381.385
06-5.147-1.51-6.8381.328
071.288-1.412-3.522-2.276
080.415-0.2270.173-0.696
09-0.450.3110.134-0.158
Standard thresholds
P-value Threshold
0.001 5.41093
0.0005 6.05508
0.0001 6.94548