DLX6.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX6.H12INVIVO.0.SM.D
Gene (human)	DLX6 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx6
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	13
Consensus	nnvnTAATTRbnn
GC content	38.25%
Information content (bits; total / per base)	11.592 / 0.892
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9618

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.964	0.943	0.906	0.886	0.811	0.809
Overall, 4 experiments	best	0.982	0.968	0.975	0.958	0.956	0.936
Methyl HT-SELEX, 1 experiments	median	0.982	0.968	0.975	0.958	0.956	0.936
Methyl HT-SELEX, 1 experiments	best	0.982	0.968	0.975	0.958	0.956	0.936
Non-Methyl HT-SELEX, 3 experiments	median	0.951	0.924	0.843	0.824	0.685	0.704
Non-Methyl HT-SELEX, 3 experiments	best	0.978	0.962	0.968	0.948	0.936	0.913

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.582	0.165	0.483	0.266

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.6
HGNC	HGNC:2919
MGI	MGI:101927
EntrezGene (human)	GeneID:1750 (SSTAR profile)
EntrezGene (mouse)	GeneID:13396 (SSTAR profile)
UniProt ID (human)	DLX6_HUMAN
UniProt ID (mouse)	DLX6_MOUSE
UniProt AC (human)	P56179 (TFClass)
UniProt AC (mouse)	P70397 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	DLX6.H12INVIVO.0.SM.D.pcm
PWM	DLX6.H12INVIVO.0.SM.D.pwm
PFM	DLX6.H12INVIVO.0.SM.D.pfm
Alignment	DLX6.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	DLX6.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	DLX6.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	DLX6.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	DLX6.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	DLX6.H12INVIVO.0.SM.D_homer_format_0.001.txt DLX6.H12INVIVO.0.SM.D_homer_format_0.0005.txt DLX6.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2325.5	2499.5	2774.5	2018.5
02	2213.75	3600.75	2289.75	1513.75
03	1791.0	3067.0	4113.0	647.0
04	1345.0	3551.0	2367.0	2355.0
05	2.0	44.0	0.0	9572.0
06	9618.0	0.0	0.0	0.0
07	9618.0	0.0	0.0	0.0
08	0.0	0.0	0.0	9618.0
09	0.0	21.0	45.0	9552.0
10	4946.0	4.0	4590.0	78.0
11	861.0	4962.0	2641.0	1154.0
12	1730.0	2461.0	3239.0	2188.0
13	1879.0	2904.0	2652.0	2183.0

PFM

	A	C	G	T
01	0.242	0.26	0.288	0.21
02	0.23	0.374	0.238	0.157
03	0.186	0.319	0.428	0.067
04	0.14	0.369	0.246	0.245
05	0.0	0.005	0.0	0.995
06	1.0	0.0	0.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.002	0.005	0.993
10	0.514	0.0	0.477	0.008
11	0.09	0.516	0.275	0.12
12	0.18	0.256	0.337	0.227
13	0.195	0.302	0.276	0.227

PWM

	A	C	G	T
01	-0.033	0.039	0.143	-0.175
02	-0.083	0.403	-0.049	-0.462
03	-0.294	0.243	0.536	-1.31
04	-0.58	0.39	-0.016	-0.021
05	-6.329	-3.951	-6.956	1.381
06	1.386	-6.956	-6.956	-6.956
07	1.386	-6.956	-6.956	-6.956
08	-6.956	-6.956	-6.956	1.386
09	-6.956	-4.638	-3.93	1.379
10	0.721	-5.947	0.646	-3.4
11	-1.025	0.724	0.094	-0.733
12	-0.329	0.023	0.298	-0.094
13	-0.246	0.189	0.098	-0.097

Standard thresholds

P-value	Threshold
0.001	2.38211
0.0005	4.54892
0.0001	7.99518