Motif | DLX5.H12CORE.0.PSM.A |
Gene (human) | DLX5 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Dlx5 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | DLX5.H12CORE.0.PSM.A |
Gene (human) | DLX5 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Dlx5 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 13 |
Consensus | nvnTAATTRSnnn |
GC content | 37.94% |
Information content (bits; total / per base) | 11.72 / 0.902 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9840 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 3 (21) | 0.86 | 0.886 | 0.768 | 0.834 | 0.785 | 0.824 | 2.443 | 2.715 | 120.678 | 163.027 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.983 | 0.971 | 0.974 | 0.958 | 0.952 | 0.932 |
best | 0.994 | 0.989 | 0.99 | 0.983 | 0.982 | 0.972 | |
Methyl HT-SELEX, 3 experiments | median | 0.986 | 0.977 | 0.979 | 0.965 | 0.962 | 0.945 |
best | 0.994 | 0.989 | 0.99 | 0.983 | 0.982 | 0.972 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.98 | 0.965 | 0.969 | 0.95 | 0.941 | 0.918 |
best | 0.991 | 0.984 | 0.986 | 0.977 | 0.975 | 0.962 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.997 | 0.883 | 0.977 | 0.597 |
batch 2 | 0.914 | 0.858 | 0.855 | 0.688 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | DLX {3.1.2.5} (TFClass) |
TFClass ID | TFClass: 3.1.2.5.5 |
HGNC | HGNC:2918 |
MGI | MGI:101926 |
EntrezGene (human) | GeneID:1749 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13395 (SSTAR profile) |
UniProt ID (human) | DLX5_HUMAN |
UniProt ID (mouse) | DLX5_MOUSE |
UniProt AC (human) | P56178 (TFClass) |
UniProt AC (mouse) | P70396 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 3 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 3 |
PCM | DLX5.H12CORE.0.PSM.A.pcm |
PWM | DLX5.H12CORE.0.PSM.A.pwm |
PFM | DLX5.H12CORE.0.PSM.A.pfm |
Alignment | DLX5.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | DLX5.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | DLX5.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | DLX5.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | DLX5.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2417.25 | 3194.25 | 2349.25 | 1879.25 |
02 | 1841.75 | 3130.75 | 4087.75 | 779.75 |
03 | 2447.0 | 3147.0 | 2186.0 | 2060.0 |
04 | 7.0 | 99.0 | 0.0 | 9734.0 |
05 | 9840.0 | 0.0 | 0.0 | 0.0 |
06 | 9840.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 9840.0 |
08 | 1.0 | 7.0 | 15.0 | 9817.0 |
09 | 5044.0 | 8.0 | 4761.0 | 27.0 |
10 | 1017.0 | 5795.0 | 2580.0 | 448.0 |
11 | 1832.0 | 2703.0 | 3006.0 | 2299.0 |
12 | 1357.0 | 3322.0 | 3072.0 | 2089.0 |
13 | 1962.75 | 2702.75 | 2369.75 | 2804.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.246 | 0.325 | 0.239 | 0.191 |
02 | 0.187 | 0.318 | 0.415 | 0.079 |
03 | 0.249 | 0.32 | 0.222 | 0.209 |
04 | 0.001 | 0.01 | 0.0 | 0.989 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 0.0 | 0.001 | 0.002 | 0.998 |
09 | 0.513 | 0.001 | 0.484 | 0.003 |
10 | 0.103 | 0.589 | 0.262 | 0.046 |
11 | 0.186 | 0.275 | 0.305 | 0.234 |
12 | 0.138 | 0.338 | 0.312 | 0.212 |
13 | 0.199 | 0.275 | 0.241 | 0.285 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.018 | 0.261 | -0.046 | -0.269 |
02 | -0.289 | 0.241 | 0.507 | -1.147 |
03 | -0.005 | 0.246 | -0.118 | -0.177 |
04 | -5.579 | -3.191 | -6.977 | 1.375 |
05 | 1.386 | -6.977 | -6.977 | -6.977 |
06 | 1.386 | -6.977 | -6.977 | -6.977 |
07 | -6.977 | -6.977 | -6.977 | 1.386 |
08 | -6.615 | -5.579 | -4.958 | 1.383 |
09 | 0.718 | -5.477 | 0.66 | -4.431 |
10 | -0.882 | 0.856 | 0.048 | -1.699 |
11 | -0.294 | 0.094 | 0.2 | -0.068 |
12 | -0.594 | 0.3 | 0.222 | -0.163 |
13 | -0.226 | 0.094 | -0.037 | 0.131 |
P-value | Threshold |
---|---|
0.001 | 2.10081 |
0.0005 | 4.39746 |
0.0001 | 8.034815 |