MotifDLX5.H12CORE.0.PSM.A
Gene (human)DLX5
(GeneCards)
Gene synonyms (human)
Gene (mouse)Dlx5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length13
ConsensusnvnTAATTRSnnn
GC content37.94%
Information content (bits; total / per base)11.72 / 0.902
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9840

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (21) 0.86 0.886 0.768 0.834 0.785 0.824 2.443 2.715 120.678 163.027

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.983 0.971 0.974 0.958 0.952 0.932
best 0.994 0.989 0.99 0.983 0.982 0.972
Methyl HT-SELEX, 3 experiments median 0.986 0.977 0.979 0.965 0.962 0.945
best 0.994 0.989 0.99 0.983 0.982 0.972
Non-Methyl HT-SELEX, 5 experiments median 0.98 0.965 0.969 0.95 0.941 0.918
best 0.991 0.984 0.986 0.977 0.975 0.962

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.997 0.883 0.977 0.597
batch 2 0.914 0.858 0.855 0.688
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyDLX {3.1.2.5} (TFClass)
TFClass IDTFClass: 3.1.2.5.5
HGNCHGNC:2918
MGIMGI:101926
EntrezGene (human)GeneID:1749
(SSTAR profile)
EntrezGene (mouse)GeneID:13395
(SSTAR profile)
UniProt ID (human)DLX5_HUMAN
UniProt ID (mouse)DLX5_MOUSE
UniProt AC (human)P56178
(TFClass)
UniProt AC (mouse)P70396
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
012417.253194.252349.251879.25
021841.753130.754087.75779.75
032447.03147.02186.02060.0
047.099.00.09734.0
059840.00.00.00.0
069840.00.00.00.0
070.00.00.09840.0
081.07.015.09817.0
095044.08.04761.027.0
101017.05795.02580.0448.0
111832.02703.03006.02299.0
121357.03322.03072.02089.0
131962.752702.752369.752804.75
PFM
ACGT
010.2460.3250.2390.191
020.1870.3180.4150.079
030.2490.320.2220.209
040.0010.010.00.989
051.00.00.00.0
061.00.00.00.0
070.00.00.01.0
080.00.0010.0020.998
090.5130.0010.4840.003
100.1030.5890.2620.046
110.1860.2750.3050.234
120.1380.3380.3120.212
130.1990.2750.2410.285
PWM
ACGT
01-0.0180.261-0.046-0.269
02-0.2890.2410.507-1.147
03-0.0050.246-0.118-0.177
04-5.579-3.191-6.9771.375
051.386-6.977-6.977-6.977
061.386-6.977-6.977-6.977
07-6.977-6.977-6.9771.386
08-6.615-5.579-4.9581.383
090.718-5.4770.66-4.431
10-0.8820.8560.048-1.699
11-0.2940.0940.2-0.068
12-0.5940.30.222-0.163
13-0.2260.094-0.0370.131
Standard thresholds
P-value Threshold
0.001 2.10081
0.0005 4.39746
0.0001 8.034815