MotifDLX4.H12INVIVO.1.S.D
Gene (human)DLX4
(GeneCards)
Gene synonyms (human)BP1, DLX7, DLX8, DLX9
Gene (mouse)Dlx4
Gene synonyms (mouse)Dlx7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length18
ConsensushWWWKdnvbTAATTAvnn
GC content27.78%
Information content (bits; total / per base)14.58 / 0.81
Data sourcesHT-SELEX
Aligned words341

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.967 0.946 0.961 0.933 0.945 0.915
best 0.987 0.977 0.982 0.969 0.976 0.961
Methyl HT-SELEX, 3 experiments median 0.973 0.953 0.963 0.939 0.947 0.919
best 0.987 0.977 0.982 0.969 0.976 0.961
Non-Methyl HT-SELEX, 5 experiments median 0.961 0.938 0.96 0.927 0.943 0.911
best 0.98 0.965 0.976 0.958 0.973 0.953

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.952 0.329 0.929 0.53
batch 2 0.88 0.707 0.833 0.598
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyDLX {3.1.2.5} (TFClass)
TFClass IDTFClass: 3.1.2.5.4
HGNCHGNC:2917
MGIMGI:94904
EntrezGene (human)GeneID:1748
(SSTAR profile)
EntrezGene (mouse)GeneID:13394
(SSTAR profile)
UniProt ID (human)DLX4_HUMAN
UniProt ID (mouse)DLX4_MOUSE
UniProt AC (human)Q92988
(TFClass)
UniProt AC (mouse)P70436
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
01135.7544.7531.75128.75
02180.7537.754.75117.75
03199.05.05.0132.0
04139.06.019.0177.0
0565.09.072.0195.0
0657.041.091.0152.0
07137.047.0110.047.0
08100.070.0129.042.0
0923.094.0160.064.0
100.013.00.0328.0
11341.00.00.00.0
12341.00.00.00.0
130.00.00.0341.0
140.00.00.0341.0
15249.00.092.00.0
1654.0129.0117.041.0
1789.7592.75100.7557.75
18100.2580.25103.2557.25
PFM
ACGT
010.3980.1310.0930.378
020.530.1110.0140.345
030.5840.0150.0150.387
040.4080.0180.0560.519
050.1910.0260.2110.572
060.1670.120.2670.446
070.4020.1380.3230.138
080.2930.2050.3780.123
090.0670.2760.4690.188
100.00.0380.00.962
111.00.00.00.0
121.00.00.00.0
130.00.00.01.0
140.00.00.01.0
150.730.00.270.0
160.1580.3780.3430.12
170.2630.2720.2950.169
180.2940.2350.3030.168
PWM
ACGT
010.459-0.629-0.960.407
020.743-0.794-2.6370.318
030.838-2.597-2.5970.431
040.482-2.453-1.4440.722
05-0.266-2.115-0.1660.818
06-0.394-0.7140.0640.571
070.468-0.5820.251-0.582
080.157-0.1930.409-0.691
09-1.2660.0960.622-0.281
10-4.086-1.791-4.0861.335
111.374-4.086-4.086-4.086
121.374-4.086-4.086-4.086
13-4.086-4.086-4.0861.374
14-4.086-4.086-4.0861.374
151.061-4.0860.075-4.086
16-0.4470.4090.312-0.714
170.0510.0830.164-0.381
180.16-0.0590.189-0.39
Standard thresholds
P-value Threshold
0.001 2.87476
0.0005 4.13081
0.0001 6.78331