DLX4.H12INVITRO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX4.H12INVITRO.1.S.C
Gene (human)	DLX4 (GeneCards)
Gene synonyms (human)	BP1, DLX7, DLX8, DLX9
Gene (mouse)	Dlx4
Gene synonyms (mouse)	Dlx7
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	18
Consensus	hWWWWdvvSTAATTASnn
GC content	29.3%
Information content (bits; total / per base)	15.07 / 0.837
Data sources	HT-SELEX
Aligned words	648

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.97	0.95	0.962	0.936	0.943	0.914
Overall, 8 experiments	best	0.985	0.976	0.98	0.966	0.974	0.957
Methyl HT-SELEX, 3 experiments	median	0.975	0.956	0.965	0.942	0.947	0.92
Methyl HT-SELEX, 3 experiments	best	0.985	0.976	0.98	0.966	0.974	0.957
Non-Methyl HT-SELEX, 5 experiments	median	0.964	0.944	0.96	0.929	0.94	0.909
Non-Methyl HT-SELEX, 5 experiments	best	0.978	0.962	0.973	0.954	0.97	0.948

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.935	0.321	0.911	0.518
batch 2	0.861	0.636	0.806	0.573

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.4
HGNC	HGNC:2917
MGI	MGI:94904
EntrezGene (human)	GeneID:1748 (SSTAR profile)
EntrezGene (mouse)	GeneID:13394 (SSTAR profile)
UniProt ID (human)	DLX4_HUMAN
UniProt ID (mouse)	DLX4_MOUSE
UniProt AC (human)	Q92988 (TFClass)
UniProt AC (mouse)	P70436 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	3

PCM	DLX4.H12INVITRO.1.S.C.pcm
PWM	DLX4.H12INVITRO.1.S.C.pwm
PFM	DLX4.H12INVITRO.1.S.C.pfm
Alignment	DLX4.H12INVITRO.1.S.C.words.tsv
Threshold to P-value map	DLX4.H12INVITRO.1.S.C.thr
Motif in other formats
JASPAR format	DLX4.H12INVITRO.1.S.C_jaspar_format.txt
MEME format	DLX4.H12INVITRO.1.S.C_meme_format.meme
Transfac format	DLX4.H12INVITRO.1.S.C_transfac_format.txt
Homer format	DLX4.H12INVITRO.1.S.C_homer_format_0.001.txt DLX4.H12INVITRO.1.S.C_homer_format_0.0005.txt DLX4.H12INVITRO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	257.5	96.5	59.5	234.5
02	349.25	38.25	4.25	256.25
03	398.0	10.0	11.0	229.0
04	273.0	17.0	25.0	333.0
05	140.0	31.0	80.0	397.0
06	152.0	62.0	162.0	272.0
07	193.0	155.0	235.0	65.0
08	191.0	135.0	242.0	80.0
09	9.0	226.0	364.0	49.0
10	0.0	87.0	0.0	561.0
11	648.0	0.0	0.0	0.0
12	648.0	0.0	0.0	0.0
13	0.0	0.0	0.0	648.0
14	0.0	0.0	0.0	648.0
15	496.0	0.0	152.0	0.0
16	104.0	286.0	245.0	13.0
17	172.75	156.75	209.75	108.75
18	191.5	139.5	188.5	128.5

PFM

	A	C	G	T
01	0.397	0.149	0.092	0.362
02	0.539	0.059	0.007	0.395
03	0.614	0.015	0.017	0.353
04	0.421	0.026	0.039	0.514
05	0.216	0.048	0.123	0.613
06	0.235	0.096	0.25	0.42
07	0.298	0.239	0.363	0.1
08	0.295	0.208	0.373	0.123
09	0.014	0.349	0.562	0.076
10	0.0	0.134	0.0	0.866
11	1.0	0.0	0.0	0.0
12	1.0	0.0	0.0	0.0
13	0.0	0.0	0.0	1.0
14	0.0	0.0	0.0	1.0
15	0.765	0.0	0.235	0.0
16	0.16	0.441	0.378	0.02
17	0.267	0.242	0.324	0.168
18	0.296	0.215	0.291	0.198

PWM

	A	C	G	T
01	0.46	-0.511	-0.985	0.367
02	0.763	-1.412	-3.328	0.455
03	0.893	-2.645	-2.562	0.343
04	0.518	-2.173	-1.816	0.715
05	-0.144	-1.613	-0.695	0.89
06	-0.063	-0.945	0.0	0.514
07	0.174	-0.044	0.369	-0.899
08	0.163	-0.18	0.398	-0.695
09	-2.735	0.33	0.804	-1.173
10	-4.616	-0.613	-4.616	1.235
11	1.379	-4.616	-4.616	-4.616
12	1.379	-4.616	-4.616	-4.616
13	-4.616	-4.616	-4.616	1.379
14	-4.616	-4.616	-4.616	1.379
15	1.112	-4.616	-0.063	-4.616
16	-0.438	0.564	0.41	-2.415
17	0.064	-0.033	0.256	-0.394
18	0.166	-0.148	0.15	-0.229

Standard thresholds

P-value	Threshold
0.001	2.18226
0.0005	3.57166
0.0001	6.51591