DLX4.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX4.H12CORE.0.SM.B
Gene (human)	DLX4 (GeneCards)
Gene synonyms (human)	BP1, DLX7, DLX8, DLX9
Gene (mouse)	Dlx4
Gene synonyms (mouse)	Dlx7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nvbTAATTRSnnn
GC content	36.46%
Information content (bits; total / per base)	11.771 / 0.905
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9779

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.983	0.971	0.977	0.961	0.962	0.943
Overall, 8 experiments	best	0.994	0.991	0.993	0.987	0.99	0.983
Methyl HT-SELEX, 3 experiments	median	0.983	0.972	0.975	0.958	0.96	0.939
Methyl HT-SELEX, 3 experiments	best	0.994	0.991	0.992	0.987	0.989	0.982
Non-Methyl HT-SELEX, 5 experiments	median	0.983	0.97	0.979	0.963	0.965	0.946
Non-Methyl HT-SELEX, 5 experiments	best	0.994	0.989	0.993	0.987	0.99	0.983

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.992	0.754	0.951	0.601
batch 2	0.943	0.833	0.852	0.634

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.4
HGNC	HGNC:2917
MGI	MGI:94904
EntrezGene (human)	GeneID:1748 (SSTAR profile)
EntrezGene (mouse)	GeneID:13394 (SSTAR profile)
UniProt ID (human)	DLX4_HUMAN
UniProt ID (mouse)	DLX4_MOUSE
UniProt AC (human)	Q92988 (TFClass)
UniProt AC (mouse)	P70436 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	3

PCM	DLX4.H12CORE.0.SM.B.pcm
PWM	DLX4.H12CORE.0.SM.B.pwm
PFM	DLX4.H12CORE.0.SM.B.pfm
Alignment	DLX4.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	DLX4.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	DLX4.H12CORE.0.SM.B_jaspar_format.txt
MEME format	DLX4.H12CORE.0.SM.B_meme_format.meme
Transfac format	DLX4.H12CORE.0.SM.B_transfac_format.txt
Homer format	DLX4.H12CORE.0.SM.B_homer_format_0.001.txt DLX4.H12CORE.0.SM.B_homer_format_0.0005.txt DLX4.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2694.25	2713.25	2167.25	2204.25
02	2054.25	2646.25	4276.25	802.25
03	1648.0	3671.0	1677.0	2783.0
04	0.0	55.0	1.0	9723.0
05	9778.0	0.0	1.0	0.0
06	9779.0	0.0	0.0	0.0
07	0.0	0.0	1.0	9778.0
08	0.0	24.0	26.0	9729.0
09	5174.0	1.0	4596.0	8.0
10	885.0	5515.0	3011.0	368.0
11	1976.0	2714.0	2588.0	2501.0
12	1520.0	3436.0	2632.0	2191.0
13	2424.5	2414.5	2182.5	2757.5

PFM

	A	C	G	T
01	0.276	0.277	0.222	0.225
02	0.21	0.271	0.437	0.082
03	0.169	0.375	0.171	0.285
04	0.0	0.006	0.0	0.994
05	1.0	0.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.002	0.003	0.995
09	0.529	0.0	0.47	0.001
10	0.091	0.564	0.308	0.038
11	0.202	0.278	0.265	0.256
12	0.155	0.351	0.269	0.224
13	0.248	0.247	0.223	0.282

PWM

	A	C	G	T
01	0.097	0.104	-0.12	-0.103
02	-0.174	0.079	0.559	-1.112
03	-0.394	0.406	-0.377	0.129
04	-6.971	-3.754	-6.61	1.38
05	1.385	-6.971	-6.61	-6.971
06	1.386	-6.971	-6.971	-6.971
07	-6.971	-6.971	-6.61	1.385
08	-6.971	-4.533	-4.46	1.38
09	0.749	-6.61	0.631	-5.471
10	-1.014	0.813	0.208	-1.888
11	-0.213	0.104	0.057	0.023
12	-0.475	0.34	0.074	-0.109
13	-0.008	-0.012	-0.113	0.12

Standard thresholds

P-value	Threshold
0.001	2.00681
0.0005	3.92863
0.0001	8.083615