DLX3.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX3.H12INVITRO.0.SM.B
Gene (human)	DLX3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nSvTAATTACvbn
GC content	38.18%
Information content (bits; total / per base)	13.987 / 1.076
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	5872

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.981	0.968	0.972	0.954	0.935	0.915
Overall, 6 experiments	best	0.99	0.983	0.984	0.974	0.963	0.95
Methyl HT-SELEX, 2 experiments	median	0.98	0.966	0.972	0.954	0.935	0.915
Methyl HT-SELEX, 2 experiments	best	0.982	0.97	0.973	0.955	0.954	0.932
Non-Methyl HT-SELEX, 4 experiments	median	0.983	0.97	0.975	0.959	0.931	0.914
Non-Methyl HT-SELEX, 4 experiments	best	0.99	0.983	0.984	0.974	0.963	0.95

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.3
HGNC	HGNC:2916
MGI	MGI:94903
EntrezGene (human)	GeneID:1747 (SSTAR profile)
EntrezGene (mouse)	GeneID:13393 (SSTAR profile)
UniProt ID (human)	DLX3_HUMAN
UniProt ID (mouse)	DLX3_MOUSE
UniProt AC (human)	O60479 (TFClass)
UniProt AC (mouse)	Q64205 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	DLX3.H12INVITRO.0.SM.B.pcm
PWM	DLX3.H12INVITRO.0.SM.B.pwm
PFM	DLX3.H12INVITRO.0.SM.B.pfm
Alignment	DLX3.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	DLX3.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	DLX3.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	DLX3.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	DLX3.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	DLX3.H12INVITRO.0.SM.B_homer_format_0.001.txt DLX3.H12INVITRO.0.SM.B_homer_format_0.0005.txt DLX3.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1496.5	2185.5	1105.5	1084.5
02	803.75	1731.75	3208.75	127.75
03	1750.0	2316.0	978.0	828.0
04	0.0	0.0	0.0	5872.0
05	5872.0	0.0	0.0	0.0
06	5872.0	0.0	0.0	0.0
07	0.0	0.0	0.0	5872.0
08	0.0	0.0	0.0	5872.0
09	5078.0	0.0	794.0	0.0
10	0.0	5309.0	563.0	0.0
11	1023.0	1917.0	2066.0	866.0
12	427.75	2586.75	1504.75	1352.75
13	1207.25	1749.25	1127.25	1788.25

PFM

	A	C	G	T
01	0.255	0.372	0.188	0.185
02	0.137	0.295	0.546	0.022
03	0.298	0.394	0.167	0.141
04	0.0	0.0	0.0	1.0
05	1.0	0.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.865	0.0	0.135	0.0
10	0.0	0.904	0.096	0.0
11	0.174	0.326	0.352	0.147
12	0.073	0.441	0.256	0.23
13	0.206	0.298	0.192	0.305

PWM

	A	C	G	T
01	0.019	0.397	-0.283	-0.302
02	-0.601	0.165	0.781	-2.426
03	0.175	0.455	-0.405	-0.572
04	-6.519	-6.519	-6.519	1.385
05	1.385	-6.519	-6.519	-6.519
06	1.385	-6.519	-6.519	-6.519
07	-6.519	-6.519	-6.519	1.385
08	-6.519	-6.519	-6.519	1.385
09	1.24	-6.519	-0.613	-6.519
10	-6.519	1.284	-0.956	-6.519
11	-0.361	0.267	0.341	-0.527
12	-1.23	0.566	0.025	-0.082
13	-0.195	0.175	-0.264	0.197

Standard thresholds

P-value	Threshold
0.001	0.716115
0.0005	1.9263
0.0001	7.05019