DLX3.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX3.H12CORE.1.S.B
Gene (human)	DLX3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	hhWWhnvvbTAATTAShn
GC content	30.79%
Information content (bits; total / per base)	14.181 / 0.788
Data sources	HT-SELEX
Aligned words	737

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.973	0.952	0.965	0.941	0.93	0.904
Overall, 6 experiments	best	0.979	0.962	0.968	0.948	0.954	0.929
Methyl HT-SELEX, 2 experiments	median	0.969	0.946	0.959	0.932	0.93	0.902
Methyl HT-SELEX, 2 experiments	best	0.976	0.959	0.963	0.941	0.946	0.912
Non-Methyl HT-SELEX, 4 experiments	median	0.973	0.952	0.967	0.944	0.932	0.91
Non-Methyl HT-SELEX, 4 experiments	best	0.979	0.962	0.968	0.948	0.954	0.929

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.3
HGNC	HGNC:2916
MGI	MGI:94903
EntrezGene (human)	GeneID:1747 (SSTAR profile)
EntrezGene (mouse)	GeneID:13393 (SSTAR profile)
UniProt ID (human)	DLX3_HUMAN
UniProt ID (mouse)	DLX3_MOUSE
UniProt AC (human)	O60479 (TFClass)
UniProt AC (mouse)	Q64205 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	DLX3.H12CORE.1.S.B.pcm
PWM	DLX3.H12CORE.1.S.B.pwm
PFM	DLX3.H12CORE.1.S.B.pfm
Alignment	DLX3.H12CORE.1.S.B.words.tsv
Threshold to P-value map	DLX3.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	DLX3.H12CORE.1.S.B_jaspar_format.txt
MEME format	DLX3.H12CORE.1.S.B_meme_format.meme
Transfac format	DLX3.H12CORE.1.S.B_transfac_format.txt
Homer format	DLX3.H12CORE.1.S.B_homer_format_0.001.txt DLX3.H12CORE.1.S.B_homer_format_0.0005.txt DLX3.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	327.5	108.5	69.5	231.5
02	326.5	93.5	27.5	289.5
03	387.0	22.0	21.0	307.0
04	326.0	35.0	47.0	329.0
05	188.0	104.0	73.0	372.0
06	183.0	148.0	125.0	281.0
07	279.0	220.0	170.0	68.0
08	254.0	252.0	145.0	86.0
09	35.0	367.0	241.0	94.0
10	0.0	188.0	0.0	549.0
11	736.0	1.0	0.0	0.0
12	737.0	0.0	0.0	0.0
13	0.0	0.0	0.0	737.0
14	0.0	0.0	1.0	736.0
15	636.0	0.0	101.0	0.0
16	78.0	449.0	182.0	28.0
17	120.0	360.0	112.0	145.0
18	176.5	285.5	136.5	138.5

PFM

	A	C	G	T
01	0.444	0.147	0.094	0.314
02	0.443	0.127	0.037	0.393
03	0.525	0.03	0.028	0.417
04	0.442	0.047	0.064	0.446
05	0.255	0.141	0.099	0.505
06	0.248	0.201	0.17	0.381
07	0.379	0.299	0.231	0.092
08	0.345	0.342	0.197	0.117
09	0.047	0.498	0.327	0.128
10	0.0	0.255	0.0	0.745
11	0.999	0.001	0.0	0.0
12	1.0	0.0	0.0	0.0
13	0.0	0.0	0.0	1.0
14	0.0	0.0	0.001	0.999
15	0.863	0.0	0.137	0.0
16	0.106	0.609	0.247	0.038
17	0.163	0.488	0.152	0.197
18	0.239	0.387	0.185	0.188

PWM

	A	C	G	T
01	0.571	-0.523	-0.96	0.226
02	0.568	-0.67	-1.853	0.449
03	0.737	-2.062	-2.105	0.507
04	0.567	-1.624	-1.341	0.576
05	0.02	-0.565	-0.912	0.698
06	-0.007	-0.217	-0.384	0.419
07	0.412	0.176	-0.08	-0.982
08	0.319	0.311	-0.237	-0.752
09	-1.624	0.685	0.266	-0.665
10	-4.724	0.02	-4.724	1.086
11	1.378	-4.25	-4.724	-4.724
12	1.38	-4.724	-4.724	-4.724
13	-4.724	-4.724	-4.724	1.38
14	-4.724	-4.724	-4.25	1.378
15	1.233	-4.724	-0.594	-4.724
16	-0.848	0.885	-0.012	-1.836
17	-0.424	0.665	-0.492	-0.237
18	-0.043	0.435	-0.297	-0.282

Standard thresholds

P-value	Threshold
0.001	2.68191
0.0005	4.04286
0.0001	6.98176