DLX2.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX2.H12INVIVO.0.PSM.A
Gene (human)	DLX2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx2
Gene synonyms (mouse)	Tes-1, Tes1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	TAATTRChb
GC content	27.35%
Information content (bits; total / per base)	10.659 / 1.184
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (21)	0.876	0.902	0.774	0.803	0.842	0.863	2.777	2.924	122.237	159.174

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.978	0.959	0.975	0.955	0.953	0.932
Overall, 8 experiments	best	0.985	0.97	0.983	0.968	0.977	0.961
Methyl HT-SELEX, 2 experiments	median	0.982	0.965	0.978	0.961	0.965	0.946
Methyl HT-SELEX, 2 experiments	best	0.985	0.97	0.983	0.968	0.977	0.961
Non-Methyl HT-SELEX, 6 experiments	median	0.968	0.942	0.949	0.923	0.89	0.866
Non-Methyl HT-SELEX, 6 experiments	best	0.982	0.967	0.979	0.962	0.971	0.952

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.77	0.57	0.757	0.592

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.2
HGNC	HGNC:2915
MGI	MGI:94902
EntrezGene (human)	GeneID:1746 (SSTAR profile)
EntrezGene (mouse)	GeneID:13392 (SSTAR profile)
UniProt ID (human)	DLX2_HUMAN
UniProt ID (mouse)	DLX2_MOUSE
UniProt AC (human)	Q07687 (TFClass)
UniProt AC (mouse)	P40764 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	DLX2.H12INVIVO.0.PSM.A.pcm
PWM	DLX2.H12INVIVO.0.PSM.A.pwm
PFM	DLX2.H12INVIVO.0.PSM.A.pfm
Alignment	DLX2.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	DLX2.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	DLX2.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	DLX2.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	DLX2.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	DLX2.H12INVIVO.0.PSM.A_homer_format_0.001.txt DLX2.H12INVIVO.0.PSM.A_homer_format_0.0005.txt DLX2.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	56.0	20.0	8.0	915.0
02	913.0	18.0	62.0	6.0
03	990.0	2.0	2.0	5.0
04	5.0	6.0	6.0	982.0
05	7.0	51.0	72.0	869.0
06	640.0	6.0	344.0	9.0
07	13.0	735.0	248.0	3.0
08	477.0	184.0	19.0	319.0
09	117.0	180.0	496.0	206.0

PFM

	A	C	G	T
01	0.056	0.02	0.008	0.916
02	0.914	0.018	0.062	0.006
03	0.991	0.002	0.002	0.005
04	0.005	0.006	0.006	0.983
05	0.007	0.051	0.072	0.87
06	0.641	0.006	0.344	0.009
07	0.013	0.736	0.248	0.003
08	0.477	0.184	0.019	0.319
09	0.117	0.18	0.496	0.206

PWM

	A	C	G	T
01	-1.472	-2.449	-3.252	1.293
02	1.291	-2.545	-1.373	-3.483
03	1.372	-4.212	-4.212	-3.621
04	-3.621	-3.483	-3.483	1.364
05	-3.361	-1.562	-1.227	1.242
06	0.937	-3.483	0.318	-3.155
07	-2.838	1.075	-0.007	-3.974
08	0.644	-0.303	-2.496	0.243
09	-0.751	-0.325	0.683	-0.191

Standard thresholds

P-value	Threshold
0.001	4.52882
0.0005	5.42343
0.0001	7.54711