| Motif | DLX2.H12CORE.1.S.B |
| Gene (human) | DLX2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Dlx2 |
| Gene synonyms (mouse) | Tes-1, Tes1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | DLX2.H12CORE.1.S.B |
| Gene (human) | DLX2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Dlx2 |
| Gene synonyms (mouse) | Tes-1, Tes1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 20 |
| Consensus | nnvbTAATTAvnnnhWWWdd |
| GC content | 29.02% |
| Information content (bits; total / per base) | 13.739 / 0.687 |
| Data sources | HT-SELEX |
| Aligned words | 9958 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 3 (21) | 0.846 | 0.87 | 0.701 | 0.738 | 0.801 | 0.826 | 2.659 | 2.828 | 108.319 | 155.051 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.97 | 0.948 | 0.963 | 0.936 | 0.95 | 0.921 |
| best | 0.993 | 0.987 | 0.99 | 0.983 | 0.978 | 0.968 | |
| Methyl HT-SELEX, 2 experiments | median | 0.976 | 0.959 | 0.968 | 0.947 | 0.959 | 0.934 |
| best | 0.982 | 0.968 | 0.977 | 0.96 | 0.97 | 0.951 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.97 | 0.946 | 0.951 | 0.929 | 0.897 | 0.871 |
| best | 0.993 | 0.987 | 0.99 | 0.983 | 0.978 | 0.968 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.796 | 0.719 | 0.81 | 0.648 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | DLX {3.1.2.5} (TFClass) |
| TFClass ID | TFClass: 3.1.2.5.2 |
| HGNC | HGNC:2915 |
| MGI | MGI:94902 |
| EntrezGene (human) | GeneID:1746 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:13392 (SSTAR profile) |
| UniProt ID (human) | DLX2_HUMAN |
| UniProt ID (mouse) | DLX2_MOUSE |
| UniProt AC (human) | Q07687 (TFClass) |
| UniProt AC (mouse) | P40764 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 3 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | DLX2.H12CORE.1.S.B.pcm |
| PWM | DLX2.H12CORE.1.S.B.pwm |
| PFM | DLX2.H12CORE.1.S.B.pfm |
| Alignment | DLX2.H12CORE.1.S.B.words.tsv |
| Threshold to P-value map | DLX2.H12CORE.1.S.B.thr |
| Motif in other formats | |
| JASPAR format | DLX2.H12CORE.1.S.B_jaspar_format.txt |
| MEME format | DLX2.H12CORE.1.S.B_meme_format.meme |
| Transfac format | DLX2.H12CORE.1.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2798.75 | 1965.75 | 2933.75 | 2259.75 |
| 02 | 3110.5 | 1944.5 | 3249.5 | 1653.5 |
| 03 | 2870.0 | 1720.0 | 4188.0 | 1180.0 |
| 04 | 1134.0 | 3337.0 | 3454.0 | 2033.0 |
| 05 | 2.0 | 2103.0 | 0.0 | 7853.0 |
| 06 | 9924.0 | 25.0 | 9.0 | 0.0 |
| 07 | 9958.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 0.0 | 9958.0 |
| 09 | 0.0 | 5.0 | 21.0 | 9932.0 |
| 10 | 7807.0 | 3.0 | 2147.0 | 1.0 |
| 11 | 1843.0 | 3709.0 | 3054.0 | 1352.0 |
| 12 | 1416.0 | 3295.0 | 2429.0 | 2818.0 |
| 13 | 1535.0 | 3003.0 | 2329.0 | 3091.0 |
| 14 | 3090.0 | 2432.0 | 1398.0 | 3038.0 |
| 15 | 4677.0 | 1476.0 | 840.0 | 2965.0 |
| 16 | 5150.0 | 844.0 | 456.0 | 3508.0 |
| 17 | 4448.0 | 354.0 | 242.0 | 4914.0 |
| 18 | 4068.0 | 165.0 | 357.0 | 5368.0 |
| 19 | 3586.75 | 645.75 | 852.75 | 4872.75 |
| 20 | 3054.75 | 1327.75 | 1490.75 | 4084.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.281 | 0.197 | 0.295 | 0.227 |
| 02 | 0.312 | 0.195 | 0.326 | 0.166 |
| 03 | 0.288 | 0.173 | 0.421 | 0.118 |
| 04 | 0.114 | 0.335 | 0.347 | 0.204 |
| 05 | 0.0 | 0.211 | 0.0 | 0.789 |
| 06 | 0.997 | 0.003 | 0.001 | 0.0 |
| 07 | 1.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 0.0 | 1.0 |
| 09 | 0.0 | 0.001 | 0.002 | 0.997 |
| 10 | 0.784 | 0.0 | 0.216 | 0.0 |
| 11 | 0.185 | 0.372 | 0.307 | 0.136 |
| 12 | 0.142 | 0.331 | 0.244 | 0.283 |
| 13 | 0.154 | 0.302 | 0.234 | 0.31 |
| 14 | 0.31 | 0.244 | 0.14 | 0.305 |
| 15 | 0.47 | 0.148 | 0.084 | 0.298 |
| 16 | 0.517 | 0.085 | 0.046 | 0.352 |
| 17 | 0.447 | 0.036 | 0.024 | 0.493 |
| 18 | 0.409 | 0.017 | 0.036 | 0.539 |
| 19 | 0.36 | 0.065 | 0.086 | 0.489 |
| 20 | 0.307 | 0.133 | 0.15 | 0.41 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.117 | -0.236 | 0.164 | -0.097 |
| 02 | 0.223 | -0.247 | 0.266 | -0.409 |
| 03 | 0.142 | -0.369 | 0.52 | -0.746 |
| 04 | -0.785 | 0.293 | 0.327 | -0.202 |
| 05 | -6.362 | -0.169 | -6.987 | 1.148 |
| 06 | 1.382 | -4.514 | -5.396 | -6.987 |
| 07 | 1.386 | -6.987 | -6.987 | -6.987 |
| 08 | -6.987 | -6.987 | -6.987 | 1.386 |
| 09 | -6.987 | -5.833 | -4.672 | 1.383 |
| 10 | 1.142 | -6.153 | -0.148 | -6.626 |
| 11 | -0.3 | 0.398 | 0.204 | -0.61 |
| 12 | -0.564 | 0.28 | -0.025 | 0.124 |
| 13 | -0.483 | 0.187 | -0.067 | 0.216 |
| 14 | 0.216 | -0.023 | -0.576 | 0.199 |
| 15 | 0.63 | -0.522 | -1.085 | 0.175 |
| 16 | 0.726 | -1.08 | -1.693 | 0.343 |
| 17 | 0.58 | -1.945 | -2.322 | 0.68 |
| 18 | 0.491 | -2.701 | -1.937 | 0.768 |
| 19 | 0.365 | -1.347 | -1.07 | 0.671 |
| 20 | 0.204 | -0.628 | -0.512 | 0.495 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.74291 |
| 0.0005 | 3.61256 |
| 0.0001 | 7.12626 |