MotifDLX2.H12CORE.1.S.B
Gene (human)DLX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Dlx2
Gene synonyms (mouse)Tes-1, Tes1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length20
ConsensusnnvbTAATTAvnnnhWWWdd
GC content29.02%
Information content (bits; total / per base)13.739 / 0.687
Data sourcesHT-SELEX
Aligned words9958

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (21) 0.846 0.87 0.701 0.738 0.801 0.826 2.659 2.828 108.319 155.051

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.97 0.948 0.963 0.936 0.95 0.921
best 0.993 0.987 0.99 0.983 0.978 0.968
Methyl HT-SELEX, 2 experiments median 0.976 0.959 0.968 0.947 0.959 0.934
best 0.982 0.968 0.977 0.96 0.97 0.951
Non-Methyl HT-SELEX, 6 experiments median 0.97 0.946 0.951 0.929 0.897 0.871
best 0.993 0.987 0.99 0.983 0.978 0.968

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.796 0.719 0.81 0.648
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyDLX {3.1.2.5} (TFClass)
TFClass IDTFClass: 3.1.2.5.2
HGNCHGNC:2915
MGIMGI:94902
EntrezGene (human)GeneID:1746
(SSTAR profile)
EntrezGene (mouse)GeneID:13392
(SSTAR profile)
UniProt ID (human)DLX2_HUMAN
UniProt ID (mouse)DLX2_MOUSE
UniProt AC (human)Q07687
(TFClass)
UniProt AC (mouse)P40764
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012798.751965.752933.752259.75
023110.51944.53249.51653.5
032870.01720.04188.01180.0
041134.03337.03454.02033.0
052.02103.00.07853.0
069924.025.09.00.0
079958.00.00.00.0
080.00.00.09958.0
090.05.021.09932.0
107807.03.02147.01.0
111843.03709.03054.01352.0
121416.03295.02429.02818.0
131535.03003.02329.03091.0
143090.02432.01398.03038.0
154677.01476.0840.02965.0
165150.0844.0456.03508.0
174448.0354.0242.04914.0
184068.0165.0357.05368.0
193586.75645.75852.754872.75
203054.751327.751490.754084.75
PFM
ACGT
010.2810.1970.2950.227
020.3120.1950.3260.166
030.2880.1730.4210.118
040.1140.3350.3470.204
050.00.2110.00.789
060.9970.0030.0010.0
071.00.00.00.0
080.00.00.01.0
090.00.0010.0020.997
100.7840.00.2160.0
110.1850.3720.3070.136
120.1420.3310.2440.283
130.1540.3020.2340.31
140.310.2440.140.305
150.470.1480.0840.298
160.5170.0850.0460.352
170.4470.0360.0240.493
180.4090.0170.0360.539
190.360.0650.0860.489
200.3070.1330.150.41
PWM
ACGT
010.117-0.2360.164-0.097
020.223-0.2470.266-0.409
030.142-0.3690.52-0.746
04-0.7850.2930.327-0.202
05-6.362-0.169-6.9871.148
061.382-4.514-5.396-6.987
071.386-6.987-6.987-6.987
08-6.987-6.987-6.9871.386
09-6.987-5.833-4.6721.383
101.142-6.153-0.148-6.626
11-0.30.3980.204-0.61
12-0.5640.28-0.0250.124
13-0.4830.187-0.0670.216
140.216-0.023-0.5760.199
150.63-0.522-1.0850.175
160.726-1.08-1.6930.343
170.58-1.945-2.3220.68
180.491-2.701-1.9370.768
190.365-1.347-1.070.671
200.204-0.628-0.5120.495
Standard thresholds
P-value Threshold
0.001 1.74291
0.0005 3.61256
0.0001 7.12626