DLX1.H12RSNP.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX1.H12RSNP.0.S.B
Gene (human)	DLX1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	nbTAATTAvnnnhhWWh
GC content	28.86%
Information content (bits; total / per base)	13.214 / 0.777
Data sources	HT-SELEX
Aligned words	8622

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.697	0.708	0.597	0.611	0.616	0.627	2.405	2.48	35.959	61.018

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.974	0.954	0.967	0.945	0.95	0.927
Overall, 10 experiments	best	0.99	0.983	0.984	0.974	0.973	0.959
Methyl HT-SELEX, 3 experiments	median	0.974	0.956	0.966	0.943	0.945	0.919
Methyl HT-SELEX, 3 experiments	best	0.977	0.96	0.972	0.951	0.964	0.941
Non-Methyl HT-SELEX, 7 experiments	median	0.974	0.954	0.969	0.946	0.956	0.935
Non-Methyl HT-SELEX, 7 experiments	best	0.99	0.983	0.984	0.974	0.973	0.959

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.992	0.492	0.951	0.474
batch 2	0.882	0.717	0.805	0.567

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.1
HGNC	HGNC:2914
MGI	MGI:94901
EntrezGene (human)	GeneID:1745 (SSTAR profile)
EntrezGene (mouse)	GeneID:13390 (SSTAR profile)
UniProt ID (human)	DLX1_HUMAN
UniProt ID (mouse)	DLX1_MOUSE
UniProt AC (human)	P56177 (TFClass)
UniProt AC (mouse)	Q64317 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	7
Methyl-HT-SELEX	3

PCM	DLX1.H12RSNP.0.S.B.pcm
PWM	DLX1.H12RSNP.0.S.B.pwm
PFM	DLX1.H12RSNP.0.S.B.pfm
Alignment	DLX1.H12RSNP.0.S.B.words.tsv
Threshold to P-value map	DLX1.H12RSNP.0.S.B.thr
Motif in other formats
JASPAR format	DLX1.H12RSNP.0.S.B_jaspar_format.txt
MEME format	DLX1.H12RSNP.0.S.B_meme_format.meme
Transfac format	DLX1.H12RSNP.0.S.B_transfac_format.txt
Homer format	DLX1.H12RSNP.0.S.B_homer_format_0.001.txt DLX1.H12RSNP.0.S.B_homer_format_0.0005.txt DLX1.H12RSNP.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1935.75	1629.75	3046.75	2009.75
02	1139.75	1993.75	3970.75	1517.75
03	0.0	794.0	0.0	7828.0
04	8622.0	0.0	0.0	0.0
05	8622.0	0.0	0.0	0.0
06	0.0	0.0	0.0	8622.0
07	0.0	0.0	0.0	8622.0
08	7256.0	0.0	1366.0	0.0
09	755.0	4191.0	3089.0	587.0
10	1191.0	2854.0	2000.0	2577.0
11	1316.0	2784.0	2276.0	2246.0
12	2737.0	2183.0	1532.0	2170.0
13	3537.0	1636.0	980.0	2469.0
14	3843.0	1083.0	682.0	3014.0
15	3637.0	787.0	450.0	3748.0
16	3426.25	572.25	571.25	4052.25
17	3216.0	968.0	858.0	3580.0

PFM

	A	C	G	T
01	0.225	0.189	0.353	0.233
02	0.132	0.231	0.461	0.176
03	0.0	0.092	0.0	0.908
04	1.0	0.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	0.0	1.0
08	0.842	0.0	0.158	0.0
09	0.088	0.486	0.358	0.068
10	0.138	0.331	0.232	0.299
11	0.153	0.323	0.264	0.26
12	0.317	0.253	0.178	0.252
13	0.41	0.19	0.114	0.286
14	0.446	0.126	0.079	0.35
15	0.422	0.091	0.052	0.435
16	0.397	0.066	0.066	0.47
17	0.373	0.112	0.1	0.415

PWM

	A	C	G	T
01	-0.107	-0.279	0.346	-0.07
02	-0.636	-0.078	0.61	-0.35
03	-6.859	-0.997	-6.859	1.289
04	1.386	-6.859	-6.859	-6.859
05	1.386	-6.859	-6.859	-6.859
06	-6.859	-6.859	-6.859	1.386
07	-6.859	-6.859	-6.859	1.386
08	1.213	-6.859	-0.456	-6.859
09	-1.047	0.664	0.36	-1.298
10	-0.592	0.28	-0.075	0.178
11	-0.493	0.256	0.054	0.041
12	0.239	0.013	-0.341	0.007
13	0.495	-0.275	-0.787	0.136
14	0.578	-0.687	-1.148	0.335
15	0.523	-1.006	-1.563	0.553
16	0.463	-1.323	-1.325	0.631
17	0.4	-0.799	-0.92	0.507

Standard thresholds

P-value	Threshold
0.001	1.52581
0.0005	4.10706
0.0001	7.37336