MotifDLX1.H12INVIVO.0.S.B
Gene (human)DLX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Dlx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusnbTAATTASnbnhhWWh
GC content29.06%
Information content (bits; total / per base)13.838 / 0.814
Data sourcesHT-SELEX
Aligned words6970

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.697 0.709 0.598 0.613 0.616 0.629 2.395 2.453 39.076 61.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.975 0.956 0.968 0.945 0.95 0.927
best 0.991 0.984 0.985 0.976 0.974 0.961
Methyl HT-SELEX, 3 experiments median 0.974 0.957 0.966 0.943 0.944 0.919
best 0.979 0.962 0.973 0.953 0.965 0.942
Non-Methyl HT-SELEX, 7 experiments median 0.975 0.955 0.97 0.947 0.956 0.935
best 0.991 0.984 0.985 0.976 0.974 0.961

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.991 0.505 0.954 0.472
batch 2 0.874 0.715 0.811 0.573
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyDLX {3.1.2.5} (TFClass)
TFClass IDTFClass: 3.1.2.5.1
HGNCHGNC:2914
MGIMGI:94901
EntrezGene (human)GeneID:1745
(SSTAR profile)
EntrezGene (mouse)GeneID:13390
(SSTAR profile)
UniProt ID (human)DLX1_HUMAN
UniProt ID (mouse)DLX1_MOUSE
UniProt AC (human)P56177
(TFClass)
UniProt AC (mouse)Q64317
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
011493.01323.02528.01626.0
02846.01626.03414.01084.0
030.0527.00.06443.0
046970.00.00.00.0
056970.00.00.00.0
060.00.00.06970.0
070.00.00.06970.0
085875.00.01095.00.0
09401.03572.02646.0351.0
10927.02417.01648.01978.0
11834.02456.01967.01713.0
122074.01899.01217.01780.0
132957.01339.0709.01965.0
143355.0800.0436.02379.0
153044.0494.0217.03215.0
162765.25359.25354.253491.25
172610.25737.25656.252966.25
PFM
ACGT
010.2140.190.3630.233
020.1210.2330.490.156
030.00.0760.00.924
041.00.00.00.0
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
080.8430.00.1570.0
090.0580.5120.380.05
100.1330.3470.2360.284
110.120.3520.2820.246
120.2980.2720.1750.255
130.4240.1920.1020.282
140.4810.1150.0630.341
150.4370.0710.0310.461
160.3970.0520.0510.501
170.3740.1060.0940.426
PWM
ACGT
01-0.154-0.2750.372-0.069
02-0.721-0.0690.672-0.474
03-6.67-1.193-6.671.307
041.385-6.67-6.67-6.67
051.385-6.67-6.67-6.67
06-6.67-6.67-6.671.385
07-6.67-6.67-6.671.385
081.214-6.67-0.464-6.67
09-1.4650.7170.417-1.597
10-0.630.327-0.0560.127
11-0.7350.3430.121-0.017
120.1740.086-0.3580.021
130.528-0.263-0.8970.12
140.655-0.777-1.3820.311
150.557-1.257-2.0740.612
160.461-1.574-1.5880.694
170.404-0.858-0.9740.531
Standard thresholds
P-value Threshold
0.001 1.36436
0.0005 3.48946
0.0001 7.10656