DLX1.H12INVIVO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX1.H12INVIVO.0.S.B
Gene (human)	DLX1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	nbTAATTASnbnhhWWh
GC content	29.06%
Information content (bits; total / per base)	13.838 / 0.814
Data sources	HT-SELEX
Aligned words	6970

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.697	0.709	0.598	0.613	0.616	0.629	2.395	2.453	39.076	61.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.975	0.956	0.968	0.945	0.95	0.927
Overall, 10 experiments	best	0.991	0.984	0.985	0.976	0.974	0.961
Methyl HT-SELEX, 3 experiments	median	0.974	0.957	0.966	0.943	0.944	0.919
Methyl HT-SELEX, 3 experiments	best	0.979	0.962	0.973	0.953	0.965	0.942
Non-Methyl HT-SELEX, 7 experiments	median	0.975	0.955	0.97	0.947	0.956	0.935
Non-Methyl HT-SELEX, 7 experiments	best	0.991	0.984	0.985	0.976	0.974	0.961

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.991	0.505	0.954	0.472
batch 2	0.874	0.715	0.811	0.573

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.1
HGNC	HGNC:2914
MGI	MGI:94901
EntrezGene (human)	GeneID:1745 (SSTAR profile)
EntrezGene (mouse)	GeneID:13390 (SSTAR profile)
UniProt ID (human)	DLX1_HUMAN
UniProt ID (mouse)	DLX1_MOUSE
UniProt AC (human)	P56177 (TFClass)
UniProt AC (mouse)	Q64317 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	7
Methyl-HT-SELEX	3

PCM	DLX1.H12INVIVO.0.S.B.pcm
PWM	DLX1.H12INVIVO.0.S.B.pwm
PFM	DLX1.H12INVIVO.0.S.B.pfm
Alignment	DLX1.H12INVIVO.0.S.B.words.tsv
Threshold to P-value map	DLX1.H12INVIVO.0.S.B.thr
Motif in other formats
JASPAR format	DLX1.H12INVIVO.0.S.B_jaspar_format.txt
MEME format	DLX1.H12INVIVO.0.S.B_meme_format.meme
Transfac format	DLX1.H12INVIVO.0.S.B_transfac_format.txt
Homer format	DLX1.H12INVIVO.0.S.B_homer_format_0.001.txt DLX1.H12INVIVO.0.S.B_homer_format_0.0005.txt DLX1.H12INVIVO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1493.0	1323.0	2528.0	1626.0
02	846.0	1626.0	3414.0	1084.0
03	0.0	527.0	0.0	6443.0
04	6970.0	0.0	0.0	0.0
05	6970.0	0.0	0.0	0.0
06	0.0	0.0	0.0	6970.0
07	0.0	0.0	0.0	6970.0
08	5875.0	0.0	1095.0	0.0
09	401.0	3572.0	2646.0	351.0
10	927.0	2417.0	1648.0	1978.0
11	834.0	2456.0	1967.0	1713.0
12	2074.0	1899.0	1217.0	1780.0
13	2957.0	1339.0	709.0	1965.0
14	3355.0	800.0	436.0	2379.0
15	3044.0	494.0	217.0	3215.0
16	2765.25	359.25	354.25	3491.25
17	2610.25	737.25	656.25	2966.25

PFM

	A	C	G	T
01	0.214	0.19	0.363	0.233
02	0.121	0.233	0.49	0.156
03	0.0	0.076	0.0	0.924
04	1.0	0.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	0.0	1.0
08	0.843	0.0	0.157	0.0
09	0.058	0.512	0.38	0.05
10	0.133	0.347	0.236	0.284
11	0.12	0.352	0.282	0.246
12	0.298	0.272	0.175	0.255
13	0.424	0.192	0.102	0.282
14	0.481	0.115	0.063	0.341
15	0.437	0.071	0.031	0.461
16	0.397	0.052	0.051	0.501
17	0.374	0.106	0.094	0.426

PWM

	A	C	G	T
01	-0.154	-0.275	0.372	-0.069
02	-0.721	-0.069	0.672	-0.474
03	-6.67	-1.193	-6.67	1.307
04	1.385	-6.67	-6.67	-6.67
05	1.385	-6.67	-6.67	-6.67
06	-6.67	-6.67	-6.67	1.385
07	-6.67	-6.67	-6.67	1.385
08	1.214	-6.67	-0.464	-6.67
09	-1.465	0.717	0.417	-1.597
10	-0.63	0.327	-0.056	0.127
11	-0.735	0.343	0.121	-0.017
12	0.174	0.086	-0.358	0.021
13	0.528	-0.263	-0.897	0.12
14	0.655	-0.777	-1.382	0.311
15	0.557	-1.257	-2.074	0.612
16	0.461	-1.574	-1.588	0.694
17	0.404	-0.858	-0.974	0.531

Standard thresholds

P-value	Threshold
0.001	1.36436
0.0005	3.48946
0.0001	7.10656