DLX1.H12CORE.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DLX1.H12CORE.1.PSM.A
Gene (human)	DLX1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dlx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	11
Consensus	nbnTAATTRvn
GC content	31.48%
Information content (bits; total / per base)	11.181 / 1.016
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	7850

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.694	0.708	0.642	0.658	0.641	0.659	2.066	2.141	39.959	72.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.985	0.974	0.979	0.965	0.96	0.944
Overall, 10 experiments	best	0.991	0.987	0.988	0.98	0.978	0.967
Methyl HT-SELEX, 3 experiments	median	0.983	0.972	0.977	0.962	0.957	0.939
Methyl HT-SELEX, 3 experiments	best	0.988	0.98	0.984	0.972	0.975	0.96
Non-Methyl HT-SELEX, 7 experiments	median	0.986	0.976	0.981	0.969	0.962	0.949
Non-Methyl HT-SELEX, 7 experiments	best	0.991	0.987	0.988	0.98	0.978	0.967

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.994	0.636	0.95	0.574
batch 2	0.916	0.711	0.86	0.635

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	DLX {3.1.2.5} (TFClass)
TFClass ID	TFClass: 3.1.2.5.1
HGNC	HGNC:2914
MGI	MGI:94901
EntrezGene (human)	GeneID:1745 (SSTAR profile)
EntrezGene (mouse)	GeneID:13390 (SSTAR profile)
UniProt ID (human)	DLX1_HUMAN
UniProt ID (mouse)	DLX1_MOUSE
UniProt AC (human)	P56177 (TFClass)
UniProt AC (mouse)	Q64317 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	7
Methyl-HT-SELEX	3

PCM	DLX1.H12CORE.1.PSM.A.pcm
PWM	DLX1.H12CORE.1.PSM.A.pwm
PFM	DLX1.H12CORE.1.PSM.A.pfm
Alignment	DLX1.H12CORE.1.PSM.A.words.tsv
Threshold to P-value map	DLX1.H12CORE.1.PSM.A.thr
Motif in other formats
JASPAR format	DLX1.H12CORE.1.PSM.A_jaspar_format.txt
MEME format	DLX1.H12CORE.1.PSM.A_meme_format.meme
Transfac format	DLX1.H12CORE.1.PSM.A_transfac_format.txt
Homer format	DLX1.H12CORE.1.PSM.A_homer_format_0.001.txt DLX1.H12CORE.1.PSM.A_homer_format_0.0005.txt DLX1.H12CORE.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2232.25	1993.25	1971.25	1653.25
02	1119.0	2059.0	3547.0	1125.0
03	2266.0	1214.0	2200.0	2170.0
04	44.0	41.0	9.0	7756.0
05	7781.0	0.0	69.0	0.0
06	7827.0	0.0	23.0	0.0
07	0.0	0.0	26.0	7824.0
08	5.0	3.0	95.0	7747.0
09	4081.0	21.0	3740.0	8.0
10	957.25	3083.25	3327.25	482.25
11	1752.0	1617.0	2142.0	2339.0

PFM

	A	C	G	T
01	0.284	0.254	0.251	0.211
02	0.143	0.262	0.452	0.143
03	0.289	0.155	0.28	0.276
04	0.006	0.005	0.001	0.988
05	0.991	0.0	0.009	0.0
06	0.997	0.0	0.003	0.0
07	0.0	0.0	0.003	0.997
08	0.001	0.0	0.012	0.987
09	0.52	0.003	0.476	0.001
10	0.122	0.393	0.424	0.061
11	0.223	0.206	0.273	0.298

PWM

	A	C	G	T
01	0.129	0.016	0.004	-0.171
02	-0.561	0.048	0.591	-0.556
03	0.144	-0.48	0.114	0.1
04	-3.749	-3.816	-5.163	1.373
05	1.377	-6.776	-3.317	-6.776
06	1.383	-6.776	-4.355	-6.776
07	-6.776	-6.776	-4.242	1.382
08	-5.603	-5.926	-3.006	1.372
09	0.732	-4.437	0.644	-5.257
10	-0.717	0.451	0.527	-1.4
11	-0.113	-0.193	0.087	0.175

Standard thresholds

P-value	Threshold
0.001	3.149115
0.0005	4.516145
0.0001	7.980275