DBP.H12RSNP.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DBP.H12RSNP.0.SM.B
Gene (human)	DBP (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dbp
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nhRTTACGTAAYbn
GC content	36.1%
Information content (bits; total / per base)	16.292 / 1.164
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9897

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	1.0	0.999	1.0	0.999	0.999	0.998
Overall, 10 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0
Methyl HT-SELEX, 2 experiments	median	0.999	0.999	0.999	0.999	0.999	0.998
Methyl HT-SELEX, 2 experiments	best	0.999	0.999	0.999	0.999	0.999	0.998
Non-Methyl HT-SELEX, 8 experiments	median	1.0	1.0	1.0	1.0	0.998	0.998
Non-Methyl HT-SELEX, 8 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.981	0.789	0.968	0.689
batch 2	0.956	0.908	0.933	0.723

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	PAR {1.1.8.2} (TFClass)
TFClass ID	TFClass: 1.1.8.2.1
HGNC	HGNC:2697
MGI	MGI:94866
EntrezGene (human)	GeneID:1628 (SSTAR profile)
EntrezGene (mouse)	GeneID:13170 (SSTAR profile)
UniProt ID (human)	DBP_HUMAN
UniProt ID (mouse)	DBP_MOUSE
UniProt AC (human)	Q10586 (TFClass)
UniProt AC (mouse)	Q60925 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	8
Methyl-HT-SELEX	2

PCM	DBP.H12RSNP.0.SM.B.pcm
PWM	DBP.H12RSNP.0.SM.B.pwm
PFM	DBP.H12RSNP.0.SM.B.pfm
Alignment	DBP.H12RSNP.0.SM.B.words.tsv
Threshold to P-value map	DBP.H12RSNP.0.SM.B.thr
Motif in other formats
JASPAR format	DBP.H12RSNP.0.SM.B_jaspar_format.txt
MEME format	DBP.H12RSNP.0.SM.B_meme_format.meme
Transfac format	DBP.H12RSNP.0.SM.B_transfac_format.txt
Homer format	DBP.H12RSNP.0.SM.B_homer_format_0.001.txt DBP.H12RSNP.0.SM.B_homer_format_0.0005.txt DBP.H12RSNP.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3231.0	2119.0	2436.0	2111.0
02	1587.75	2644.75	1303.75	4360.75
03	1400.0	1335.0	7160.0	2.0
04	4.0	0.0	1.0	9892.0
05	3.0	0.0	0.0	9894.0
06	9858.0	0.0	38.0	1.0
07	0.0	7650.0	0.0	2247.0
08	1248.0	0.0	8649.0	0.0
09	0.0	77.0	0.0	9820.0
10	9841.0	53.0	3.0	0.0
11	9893.0	0.0	2.0	2.0
12	129.0	2716.0	1609.0	5443.0
13	1095.75	3982.75	3585.75	1232.75
14	2813.5	2156.5	2500.5	2426.5

PFM

	A	C	G	T
01	0.326	0.214	0.246	0.213
02	0.16	0.267	0.132	0.441
03	0.141	0.135	0.723	0.0
04	0.0	0.0	0.0	0.999
05	0.0	0.0	0.0	1.0
06	0.996	0.0	0.004	0.0
07	0.0	0.773	0.0	0.227
08	0.126	0.0	0.874	0.0
09	0.0	0.008	0.0	0.992
10	0.994	0.005	0.0	0.0
11	1.0	0.0	0.0	0.0
12	0.013	0.274	0.163	0.55
13	0.111	0.402	0.362	0.125
14	0.284	0.218	0.253	0.245

PWM

	A	C	G	T
01	0.267	-0.155	-0.016	-0.159
02	-0.443	0.067	-0.64	0.566
03	-0.569	-0.616	1.062	-6.356
04	-5.974	-6.982	-6.621	1.385
05	-6.147	-6.982	-6.982	1.385
06	1.382	-6.982	-4.118	-6.621
07	-6.982	1.128	-6.982	-0.096
08	-0.683	-6.982	1.251	-6.982
09	-6.982	-3.441	-6.982	1.378
10	1.38	-3.802	-6.147	-6.982
11	1.385	-6.982	-6.356	-6.356
12	-2.937	0.093	-0.43	0.788
13	-0.813	0.476	0.371	-0.696
14	0.128	-0.137	0.011	-0.019

Standard thresholds

P-value	Threshold
0.001	-1.65819
0.0005	0.77986
0.0001	4.24561