DBP.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DBP.H12INVIVO.0.SM.D
Gene (human)	DBP (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dbp
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	14
Consensus	nhRTTACGTAAYvn
GC content	36.78%
Information content (bits; total / per base)	15.893 / 1.135
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9856

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	1.0	0.999	1.0	0.999	0.999	0.998
Overall, 10 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0
Methyl HT-SELEX, 2 experiments	median	0.999	0.999	0.999	0.999	0.999	0.998
Methyl HT-SELEX, 2 experiments	best	0.999	0.999	0.999	0.999	0.999	0.998
Non-Methyl HT-SELEX, 8 experiments	median	1.0	1.0	1.0	1.0	0.999	0.998
Non-Methyl HT-SELEX, 8 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.975	0.807	0.958	0.673
batch 2	0.94	0.848	0.924	0.699

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	PAR {1.1.8.2} (TFClass)
TFClass ID	TFClass: 1.1.8.2.1
HGNC	HGNC:2697
MGI	MGI:94866
EntrezGene (human)	GeneID:1628 (SSTAR profile)
EntrezGene (mouse)	GeneID:13170 (SSTAR profile)
UniProt ID (human)	DBP_HUMAN
UniProt ID (mouse)	DBP_MOUSE
UniProt AC (human)	Q10586 (TFClass)
UniProt AC (mouse)	Q60925 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	8
Methyl-HT-SELEX	2

PCM	DBP.H12INVIVO.0.SM.D.pcm
PWM	DBP.H12INVIVO.0.SM.D.pwm
PFM	DBP.H12INVIVO.0.SM.D.pfm
Alignment	DBP.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	DBP.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	DBP.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	DBP.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	DBP.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	DBP.H12INVIVO.0.SM.D_homer_format_0.001.txt DBP.H12INVIVO.0.SM.D_homer_format_0.0005.txt DBP.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2421.0	2616.0	2609.0	2210.0
02	1628.0	2816.0	1492.0	3920.0
03	1507.0	1043.0	7263.0	43.0
04	9.0	1.0	0.0	9846.0
05	5.0	2.0	9.0	9840.0
06	9703.0	1.0	152.0	0.0
07	0.0	7473.0	0.0	2383.0
08	1517.0	6.0	8333.0	0.0
09	1.0	283.0	1.0	9571.0
10	9686.0	160.0	4.0	6.0
11	9836.0	4.0	9.0	7.0
12	75.0	2378.0	1631.0	5772.0
13	1348.0	4423.0	2987.0	1098.0
14	2911.5	2076.5	2980.5	1887.5

PFM

	A	C	G	T
01	0.246	0.265	0.265	0.224
02	0.165	0.286	0.151	0.398
03	0.153	0.106	0.737	0.004
04	0.001	0.0	0.0	0.999
05	0.001	0.0	0.001	0.998
06	0.984	0.0	0.015	0.0
07	0.0	0.758	0.0	0.242
08	0.154	0.001	0.845	0.0
09	0.0	0.029	0.0	0.971
10	0.983	0.016	0.0	0.001
11	0.998	0.0	0.001	0.001
12	0.008	0.241	0.165	0.586
13	0.137	0.449	0.303	0.111
14	0.295	0.211	0.302	0.192

PWM

	A	C	G	T
01	-0.018	0.06	0.057	-0.109
02	-0.414	0.133	-0.501	0.464
03	-0.491	-0.858	1.08	-3.997
04	-5.386	-6.617	-6.978	1.385
05	-5.823	-6.352	-5.386	1.384
06	1.37	-6.617	-2.772	-6.978
07	-6.978	1.109	-6.978	-0.033
08	-0.484	-5.694	1.218	-6.978
09	-6.617	-2.157	-6.617	1.356
10	1.368	-2.721	-5.97	-5.694
11	1.384	-5.97	-5.386	-5.581
12	-3.463	-0.035	-0.412	0.851
13	-0.602	0.585	0.192	-0.807
14	0.167	-0.171	0.19	-0.266

Standard thresholds

P-value	Threshold
0.001	-0.21089
0.0005	1.67226
0.0001	5.214965