DBP.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	DBP.H12INVITRO.0.SM.B
Gene (human)	DBP (GeneCards)
Gene synonyms (human)
Gene (mouse)	Dbp
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nbRTTACGTAAb
GC content	39.66%
Information content (bits; total / per base)	14.252 / 1.188
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9954

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	1.0	1.0	1.0	0.999	0.999	0.998
Overall, 10 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0
Methyl HT-SELEX, 2 experiments	median	0.999	0.999	0.999	0.998	0.998	0.996
Methyl HT-SELEX, 2 experiments	best	0.999	0.999	0.999	0.998	0.998	0.997
Non-Methyl HT-SELEX, 8 experiments	median	1.0	1.0	1.0	1.0	0.999	0.998
Non-Methyl HT-SELEX, 8 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.915	0.403	0.874	0.546
batch 2	0.897	0.555	0.848	0.548

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	PAR {1.1.8.2} (TFClass)
TFClass ID	TFClass: 1.1.8.2.1
HGNC	HGNC:2697
MGI	MGI:94866
EntrezGene (human)	GeneID:1628 (SSTAR profile)
EntrezGene (mouse)	GeneID:13170 (SSTAR profile)
UniProt ID (human)	DBP_HUMAN
UniProt ID (mouse)	DBP_MOUSE
UniProt AC (human)	Q10586 (TFClass)
UniProt AC (mouse)	Q60925 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	8
Methyl-HT-SELEX	2

PCM	DBP.H12INVITRO.0.SM.B.pcm
PWM	DBP.H12INVITRO.0.SM.B.pwm
PFM	DBP.H12INVITRO.0.SM.B.pfm
Alignment	DBP.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	DBP.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	DBP.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	DBP.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	DBP.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	DBP.H12INVITRO.0.SM.B_homer_format_0.001.txt DBP.H12INVITRO.0.SM.B_homer_format_0.0005.txt DBP.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2025.25	3100.25	2444.25	2384.25
02	803.5	3697.5	3254.5	2198.5
03	4292.0	1262.0	4378.0	22.0
04	0.0	0.0	0.0	9954.0
05	0.0	0.0	11.0	9943.0
06	9853.0	0.0	99.0	2.0
07	0.0	9845.0	0.0	109.0
08	679.0	5.0	9270.0	0.0
09	1.0	1499.0	8.0	8446.0
10	9163.0	651.0	97.0	43.0
11	8125.5	593.5	614.5	620.5
12	1031.0	3804.0	2737.0	2382.0

PFM

	A	C	G	T
01	0.203	0.311	0.246	0.24
02	0.081	0.371	0.327	0.221
03	0.431	0.127	0.44	0.002
04	0.0	0.0	0.0	1.0
05	0.0	0.0	0.001	0.999
06	0.99	0.0	0.01	0.0
07	0.0	0.989	0.0	0.011
08	0.068	0.001	0.931	0.0
09	0.0	0.151	0.001	0.849
10	0.921	0.065	0.01	0.004
11	0.816	0.06	0.062	0.062
12	0.104	0.382	0.275	0.239

PWM

	A	C	G	T
01	-0.206	0.22	-0.018	-0.043
02	-1.129	0.396	0.268	-0.124
03	0.545	-0.678	0.565	-4.63
04	-6.987	-6.987	-6.987	1.386
05	-6.987	-6.987	-5.232	1.384
06	1.375	-6.987	-3.202	-6.361
07	-6.987	1.375	-6.987	-3.108
08	-1.296	-5.832	1.314	-6.987
09	-6.626	-0.506	-5.488	1.221
10	1.303	-1.338	-3.222	-4.007
11	1.183	-1.43	-1.396	-1.386
12	-0.88	0.424	0.095	-0.044

Standard thresholds

P-value	Threshold
0.001	1.637465
0.0005	3.298115
0.0001	6.724055