MotifCUX2.H12RSNP.1.SM.B
Gene (human)CUX2
(GeneCards)
Gene synonyms (human)CUTL2, KIAA0293
Gene (mouse)Cux2
Gene synonyms (mouse)Cutl2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusndTATCGATYMnn
GC content33.36%
Information content (bits; total / per base)14.911 / 1.147
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7035

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.837 0.87 0.797 0.828 0.805 0.839 2.755 3.011 180.114 230.585

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.982 0.97 0.882 0.883 0.694 0.734
best 0.991 0.986 0.968 0.95 0.912 0.892
Methyl HT-SELEX, 1 experiments median 0.984 0.973 0.882 0.877 0.701 0.735
best 0.984 0.973 0.882 0.877 0.701 0.735
Non-Methyl HT-SELEX, 3 experiments median 0.981 0.967 0.883 0.888 0.688 0.733
best 0.991 0.986 0.968 0.95 0.912 0.892

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.93 0.735 0.892 0.638
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.2
HGNCHGNC:19347
MGIMGI:107321
EntrezGene (human)GeneID:23316
(SSTAR profile)
EntrezGene (mouse)GeneID:13048
(SSTAR profile)
UniProt ID (human)CUX2_HUMAN
UniProt ID (mouse)CUX2_MOUSE
UniProt AC (human)O14529
(TFClass)
UniProt AC (mouse)P70298
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012128.251248.251682.251976.25
02846.0644.01824.03721.0
03360.0233.0608.05834.0
047035.00.00.00.0
050.00.00.07035.0
060.06436.00.0599.0
070.00.07035.00.0
087035.00.00.00.0
090.00.00.07035.0
10266.02160.043.04566.0
115536.0716.0225.0558.0
121046.51961.51870.52156.5
131132.252304.251518.252080.25
PFM
ACGT
010.3030.1770.2390.281
020.120.0920.2590.529
030.0510.0330.0860.829
041.00.00.00.0
050.00.00.01.0
060.00.9150.00.085
070.00.01.00.0
081.00.00.00.0
090.00.00.01.0
100.0380.3070.0060.649
110.7870.1020.0320.079
120.1490.2790.2660.307
130.1610.3280.2160.296
PWM
ACGT
010.19-0.342-0.0440.116
02-0.73-1.0020.0360.749
03-1.581-2.013-1.061.198
041.385-6.679-6.679-6.679
05-6.679-6.679-6.6791.385
06-6.6791.296-6.679-1.075
07-6.679-6.6791.385-6.679
081.385-6.679-6.679-6.679
09-6.679-6.679-6.6791.385
10-1.8820.205-3.6620.953
111.146-0.897-2.048-1.145
12-0.5180.1090.0620.204
13-0.440.27-0.1470.168
Standard thresholds
P-value Threshold
0.001 0.30066
0.0005 1.97964
0.0001 6.429685