Motif | CUX2.H12RSNP.0.P.C |
Gene (human) | CUX2 (GeneCards) |
Gene synonyms (human) | CUTL2, KIAA0293 |
Gene (mouse) | Cux2 |
Gene synonyms (mouse) | Cutl2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif | CUX2.H12RSNP.0.P.C |
Gene (human) | CUX2 (GeneCards) |
Gene synonyms (human) | CUTL2, KIAA0293 |
Gene (mouse) | Cux2 |
Gene synonyms (mouse) | Cutl2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif length | 11 |
Consensus | hnbATTGATYd |
GC content | 26.65% |
Information content (bits; total / per base) | 11.452 / 1.041 |
Data sources | ChIP-Seq |
Aligned words | 955 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 1 (5) | 0.848 | 0.885 | 0.788 | 0.827 | 0.826 | 0.86 | 3.13 | 3.394 | 205.796 | 254.745 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.938 | 0.898 | 0.847 | 0.821 | 0.675 | 0.698 |
best | 0.95 | 0.911 | 0.94 | 0.9 | 0.894 | 0.857 | |
Methyl HT-SELEX, 1 experiments | median | 0.936 | 0.89 | 0.852 | 0.822 | 0.68 | 0.701 |
best | 0.936 | 0.89 | 0.852 | 0.822 | 0.68 | 0.701 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.941 | 0.906 | 0.842 | 0.82 | 0.67 | 0.696 |
best | 0.95 | 0.911 | 0.94 | 0.9 | 0.894 | 0.857 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.884 | 0.634 | 0.839 | 0.572 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-CUT {3.1.9} (TFClass) |
TF subfamily | CUX {3.1.9.2} (TFClass) |
TFClass ID | TFClass: 3.1.9.2.2 |
HGNC | HGNC:19347 |
MGI | MGI:107321 |
EntrezGene (human) | GeneID:23316 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13048 (SSTAR profile) |
UniProt ID (human) | CUX2_HUMAN |
UniProt ID (mouse) | CUX2_MOUSE |
UniProt AC (human) | O14529 (TFClass) |
UniProt AC (mouse) | P70298 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 1 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | CUX2.H12RSNP.0.P.C.pcm |
PWM | CUX2.H12RSNP.0.P.C.pwm |
PFM | CUX2.H12RSNP.0.P.C.pfm |
Alignment | CUX2.H12RSNP.0.P.C.words.tsv |
Threshold to P-value map | CUX2.H12RSNP.0.P.C.thr |
Motif in other formats | |
JASPAR format | CUX2.H12RSNP.0.P.C_jaspar_format.txt |
MEME format | CUX2.H12RSNP.0.P.C_meme_format.meme |
Transfac format | CUX2.H12RSNP.0.P.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 190.0 | 152.0 | 138.0 | 475.0 |
02 | 130.0 | 174.0 | 130.0 | 521.0 |
03 | 76.0 | 208.0 | 219.0 | 452.0 |
04 | 907.0 | 17.0 | 12.0 | 19.0 |
05 | 25.0 | 5.0 | 53.0 | 872.0 |
06 | 13.0 | 62.0 | 20.0 | 860.0 |
07 | 3.0 | 5.0 | 940.0 | 7.0 |
08 | 926.0 | 11.0 | 5.0 | 13.0 |
09 | 22.0 | 52.0 | 9.0 | 872.0 |
10 | 14.0 | 238.0 | 18.0 | 685.0 |
11 | 212.0 | 95.0 | 237.0 | 411.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.199 | 0.159 | 0.145 | 0.497 |
02 | 0.136 | 0.182 | 0.136 | 0.546 |
03 | 0.08 | 0.218 | 0.229 | 0.473 |
04 | 0.95 | 0.018 | 0.013 | 0.02 |
05 | 0.026 | 0.005 | 0.055 | 0.913 |
06 | 0.014 | 0.065 | 0.021 | 0.901 |
07 | 0.003 | 0.005 | 0.984 | 0.007 |
08 | 0.97 | 0.012 | 0.005 | 0.014 |
09 | 0.023 | 0.054 | 0.009 | 0.913 |
10 | 0.015 | 0.249 | 0.019 | 0.717 |
11 | 0.222 | 0.099 | 0.248 | 0.43 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.227 | -0.447 | -0.543 | 0.684 |
02 | -0.602 | -0.314 | -0.602 | 0.776 |
03 | -1.13 | -0.137 | -0.086 | 0.635 |
04 | 1.329 | -2.553 | -2.864 | -2.452 |
05 | -2.197 | -3.578 | -1.48 | 1.29 |
06 | -2.794 | -1.328 | -2.405 | 1.276 |
07 | -3.932 | -3.578 | 1.365 | -3.317 |
08 | 1.35 | -2.94 | -3.578 | -2.794 |
09 | -2.316 | -1.499 | -3.111 | 1.29 |
10 | -2.728 | -0.003 | -2.501 | 1.049 |
11 | -0.118 | -0.911 | -0.007 | 0.54 |
P-value | Threshold |
---|---|
0.001 | 4.34812 |
0.0005 | 5.264755 |
0.0001 | 7.25792 |