MotifCUX2.H12RSNP.0.P.C
Gene (human)CUX2
(GeneCards)
Gene synonyms (human)CUTL2, KIAA0293
Gene (mouse)Cux2
Gene synonyms (mouse)Cutl2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length11
ConsensushnbATTGATYd
GC content26.65%
Information content (bits; total / per base)11.452 / 1.041
Data sourcesChIP-Seq
Aligned words955

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.848 0.885 0.788 0.827 0.826 0.86 3.13 3.394 205.796 254.745

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.938 0.898 0.847 0.821 0.675 0.698
best 0.95 0.911 0.94 0.9 0.894 0.857
Methyl HT-SELEX, 1 experiments median 0.936 0.89 0.852 0.822 0.68 0.701
best 0.936 0.89 0.852 0.822 0.68 0.701
Non-Methyl HT-SELEX, 3 experiments median 0.941 0.906 0.842 0.82 0.67 0.696
best 0.95 0.911 0.94 0.9 0.894 0.857

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.884 0.634 0.839 0.572
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.2
HGNCHGNC:19347
MGIMGI:107321
EntrezGene (human)GeneID:23316
(SSTAR profile)
EntrezGene (mouse)GeneID:13048
(SSTAR profile)
UniProt ID (human)CUX2_HUMAN
UniProt ID (mouse)CUX2_MOUSE
UniProt AC (human)O14529
(TFClass)
UniProt AC (mouse)P70298
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01190.0152.0138.0475.0
02130.0174.0130.0521.0
0376.0208.0219.0452.0
04907.017.012.019.0
0525.05.053.0872.0
0613.062.020.0860.0
073.05.0940.07.0
08926.011.05.013.0
0922.052.09.0872.0
1014.0238.018.0685.0
11212.095.0237.0411.0
PFM
ACGT
010.1990.1590.1450.497
020.1360.1820.1360.546
030.080.2180.2290.473
040.950.0180.0130.02
050.0260.0050.0550.913
060.0140.0650.0210.901
070.0030.0050.9840.007
080.970.0120.0050.014
090.0230.0540.0090.913
100.0150.2490.0190.717
110.2220.0990.2480.43
PWM
ACGT
01-0.227-0.447-0.5430.684
02-0.602-0.314-0.6020.776
03-1.13-0.137-0.0860.635
041.329-2.553-2.864-2.452
05-2.197-3.578-1.481.29
06-2.794-1.328-2.4051.276
07-3.932-3.5781.365-3.317
081.35-2.94-3.578-2.794
09-2.316-1.499-3.1111.29
10-2.728-0.003-2.5011.049
11-0.118-0.911-0.0070.54
Standard thresholds
P-value Threshold
0.001 4.34812
0.0005 5.264755
0.0001 7.25792