MotifCUX2.H12INVITRO.2.S.C
Gene (human)CUX2
(GeneCards)
Gene synonyms (human)CUTL2, KIAA0293
Gene (mouse)Cux2
Gene synonyms (mouse)Cutl2
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length13
ConsensushdRKTGATCASnn
GC content43.01%
Information content (bits; total / per base)12.566 / 0.967
Data sourcesHT-SELEX
Aligned words8253

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.804 0.82 0.703 0.726 0.636 0.664 1.702 1.831 128.066 160.495

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.966 0.95 0.867 0.854 0.696 0.723
best 0.992 0.988 0.985 0.977 0.966 0.954
Methyl HT-SELEX, 1 experiments median 0.99 0.986 0.901 0.896 0.711 0.747
best 0.99 0.986 0.901 0.896 0.711 0.747
Non-Methyl HT-SELEX, 3 experiments median 0.942 0.915 0.833 0.813 0.682 0.698
best 0.992 0.988 0.985 0.977 0.966 0.954

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.82 0.404 0.727 0.487
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.2
HGNCHGNC:19347
MGIMGI:107321
EntrezGene (human)GeneID:23316
(SSTAR profile)
EntrezGene (mouse)GeneID:13048
(SSTAR profile)
UniProt ID (human)CUX2_HUMAN
UniProt ID (mouse)CUX2_MOUSE
UniProt AC (human)O14529
(TFClass)
UniProt AC (mouse)P70298
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011526.752427.751205.753092.75
023581.75594.752250.751825.75
036128.0334.01443.0348.0
042.01197.01277.05777.0
052.03686.02.04563.0
060.00.08253.00.0
078253.00.00.00.0
080.01.00.08252.0
0910.07004.00.01239.0
106324.01.01925.03.0
11591.01102.06257.0303.0
121194.02277.01755.03027.0
132300.51272.51875.52804.5
PFM
ACGT
010.1850.2940.1460.375
020.4340.0720.2730.221
030.7430.040.1750.042
040.00.1450.1550.7
050.00.4470.00.553
060.00.01.00.0
071.00.00.00.0
080.00.00.01.0
090.0010.8490.00.15
100.7660.00.2330.0
110.0720.1340.7580.037
120.1450.2760.2130.367
130.2790.1540.2270.34
PWM
ACGT
01-0.3010.163-0.5360.404
020.551-1.2410.087-0.122
031.088-1.815-0.357-1.774
04-6.185-0.544-0.4791.029
05-6.1850.58-6.1850.793
06-6.82-6.821.385-6.82
071.385-6.82-6.82-6.82
08-6.82-6.453-6.821.385
09-5.1271.221-6.82-0.509
101.119-6.453-0.069-5.974
11-1.248-0.6261.109-1.912
12-0.5460.098-0.1620.383
130.109-0.483-0.0950.307
Standard thresholds
P-value Threshold
0.001 3.019965
0.0005 4.89201
0.0001 7.477135