Motif | CUX2.H12INVITRO.0.P.C |
Gene (human) | CUX2 (GeneCards) |
Gene synonyms (human) | CUTL2, KIAA0293 |
Gene (mouse) | Cux2 |
Gene synonyms (mouse) | Cutl2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif | CUX2.H12INVITRO.0.P.C |
Gene (human) | CUX2 (GeneCards) |
Gene synonyms (human) | CUTL2, KIAA0293 |
Gene (mouse) | Cux2 |
Gene synonyms (mouse) | Cutl2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif length | 10 |
Consensus | bbATTGATYd |
GC content | 26.09% |
Information content (bits; total / per base) | 11.457 / 1.146 |
Data sources | ChIP-Seq |
Aligned words | 962 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 1 (5) | 0.853 | 0.891 | 0.793 | 0.838 | 0.827 | 0.861 | 3.014 | 3.245 | 213.745 | 256.027 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.942 | 0.902 | 0.854 | 0.829 | 0.679 | 0.703 |
best | 0.952 | 0.915 | 0.949 | 0.91 | 0.903 | 0.868 | |
Methyl HT-SELEX, 1 experiments | median | 0.942 | 0.895 | 0.858 | 0.83 | 0.685 | 0.706 |
best | 0.942 | 0.895 | 0.858 | 0.83 | 0.685 | 0.706 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.943 | 0.909 | 0.849 | 0.828 | 0.674 | 0.701 |
best | 0.952 | 0.915 | 0.949 | 0.91 | 0.903 | 0.868 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.888 | 0.627 | 0.848 | 0.569 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-CUT {3.1.9} (TFClass) |
TF subfamily | CUX {3.1.9.2} (TFClass) |
TFClass ID | TFClass: 3.1.9.2.2 |
HGNC | HGNC:19347 |
MGI | MGI:107321 |
EntrezGene (human) | GeneID:23316 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13048 (SSTAR profile) |
UniProt ID (human) | CUX2_HUMAN |
UniProt ID (mouse) | CUX2_MOUSE |
UniProt AC (human) | O14529 (TFClass) |
UniProt AC (mouse) | P70298 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 1 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | CUX2.H12INVITRO.0.P.C.pcm |
PWM | CUX2.H12INVITRO.0.P.C.pwm |
PFM | CUX2.H12INVITRO.0.P.C.pfm |
Alignment | CUX2.H12INVITRO.0.P.C.words.tsv |
Threshold to P-value map | CUX2.H12INVITRO.0.P.C.thr |
Motif in other formats | |
JASPAR format | CUX2.H12INVITRO.0.P.C_jaspar_format.txt |
MEME format | CUX2.H12INVITRO.0.P.C_meme_format.meme |
Transfac format | CUX2.H12INVITRO.0.P.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 124.0 | 177.0 | 142.0 | 519.0 |
02 | 69.0 | 205.0 | 209.0 | 479.0 |
03 | 927.0 | 13.0 | 10.0 | 12.0 |
04 | 14.0 | 6.0 | 50.0 | 892.0 |
05 | 12.0 | 62.0 | 20.0 | 868.0 |
06 | 4.0 | 1.0 | 948.0 | 9.0 |
07 | 934.0 | 9.0 | 8.0 | 11.0 |
08 | 26.0 | 45.0 | 8.0 | 883.0 |
09 | 21.0 | 237.0 | 17.0 | 687.0 |
10 | 201.0 | 92.0 | 251.0 | 418.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.129 | 0.184 | 0.148 | 0.54 |
02 | 0.072 | 0.213 | 0.217 | 0.498 |
03 | 0.964 | 0.014 | 0.01 | 0.012 |
04 | 0.015 | 0.006 | 0.052 | 0.927 |
05 | 0.012 | 0.064 | 0.021 | 0.902 |
06 | 0.004 | 0.001 | 0.985 | 0.009 |
07 | 0.971 | 0.009 | 0.008 | 0.011 |
08 | 0.027 | 0.047 | 0.008 | 0.918 |
09 | 0.022 | 0.246 | 0.018 | 0.714 |
10 | 0.209 | 0.096 | 0.261 | 0.435 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.656 | -0.304 | -0.522 | 0.765 |
02 | -1.231 | -0.158 | -0.139 | 0.685 |
03 | 1.344 | -2.801 | -3.029 | -2.871 |
04 | -2.735 | -3.446 | -1.544 | 1.306 |
05 | -2.871 | -1.335 | -2.412 | 1.278 |
06 | -3.746 | -4.49 | 1.366 | -3.118 |
07 | 1.351 | -3.118 | -3.216 | -2.947 |
08 | -2.168 | -1.646 | -3.216 | 1.295 |
09 | -2.367 | -0.015 | -2.56 | 1.045 |
10 | -0.178 | -0.95 | 0.042 | 0.55 |
P-value | Threshold |
---|---|
0.001 | 4.34681 |
0.0005 | 5.26251 |
0.0001 | 7.30093 |