MotifCUX2.H12INVITRO.0.P.C
Gene (human)CUX2
(GeneCards)
Gene synonyms (human)CUTL2, KIAA0293
Gene (mouse)Cux2
Gene synonyms (mouse)Cutl2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length10
ConsensusbbATTGATYd
GC content26.09%
Information content (bits; total / per base)11.457 / 1.146
Data sourcesChIP-Seq
Aligned words962

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.853 0.891 0.793 0.838 0.827 0.861 3.014 3.245 213.745 256.027

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.942 0.902 0.854 0.829 0.679 0.703
best 0.952 0.915 0.949 0.91 0.903 0.868
Methyl HT-SELEX, 1 experiments median 0.942 0.895 0.858 0.83 0.685 0.706
best 0.942 0.895 0.858 0.83 0.685 0.706
Non-Methyl HT-SELEX, 3 experiments median 0.943 0.909 0.849 0.828 0.674 0.701
best 0.952 0.915 0.949 0.91 0.903 0.868

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.888 0.627 0.848 0.569
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.2
HGNCHGNC:19347
MGIMGI:107321
EntrezGene (human)GeneID:23316
(SSTAR profile)
EntrezGene (mouse)GeneID:13048
(SSTAR profile)
UniProt ID (human)CUX2_HUMAN
UniProt ID (mouse)CUX2_MOUSE
UniProt AC (human)O14529
(TFClass)
UniProt AC (mouse)P70298
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01124.0177.0142.0519.0
0269.0205.0209.0479.0
03927.013.010.012.0
0414.06.050.0892.0
0512.062.020.0868.0
064.01.0948.09.0
07934.09.08.011.0
0826.045.08.0883.0
0921.0237.017.0687.0
10201.092.0251.0418.0
PFM
ACGT
010.1290.1840.1480.54
020.0720.2130.2170.498
030.9640.0140.010.012
040.0150.0060.0520.927
050.0120.0640.0210.902
060.0040.0010.9850.009
070.9710.0090.0080.011
080.0270.0470.0080.918
090.0220.2460.0180.714
100.2090.0960.2610.435
PWM
ACGT
01-0.656-0.304-0.5220.765
02-1.231-0.158-0.1390.685
031.344-2.801-3.029-2.871
04-2.735-3.446-1.5441.306
05-2.871-1.335-2.4121.278
06-3.746-4.491.366-3.118
071.351-3.118-3.216-2.947
08-2.168-1.646-3.2161.295
09-2.367-0.015-2.561.045
10-0.178-0.950.0420.55
Standard thresholds
P-value Threshold
0.001 4.34681
0.0005 5.26251
0.0001 7.30093