MotifCUX1.H12INVIVO.1.S.B
Gene (human)CUX1
(GeneCards)
Gene synonyms (human)CUTL1
Gene (mouse)Cux1
Gene synonyms (mouse)Cutl1, Cux, Kiaa4047
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusnbKATCGATYRnnn
GC content38.2%
Information content (bits; total / per base)13.61 / 0.972
Data sourcesHT-SELEX
Aligned words8038

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (32) 0.856 0.928 0.799 0.897 0.784 0.892 2.503 3.43 217.298 345.602

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.991 0.983 0.987 0.978 0.962 0.944
best 0.998 0.997 0.998 0.996 0.996 0.993
Methyl HT-SELEX, 1 experiments median 0.989 0.978 0.986 0.975 0.983 0.97
best 0.989 0.978 0.986 0.975 0.983 0.97
Non-Methyl HT-SELEX, 3 experiments median 0.993 0.988 0.988 0.98 0.942 0.919
best 0.998 0.997 0.998 0.996 0.996 0.993

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.947 0.848 0.934 0.646
batch 2 0.906 0.785 0.88 0.626
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.1
HGNCHGNC:2557
MGIMGI:88568
EntrezGene (human)GeneID:1523
(SSTAR profile)
EntrezGene (mouse)GeneID:13047
(SSTAR profile)
UniProt ID (human)CUX1_HUMAN
UniProt ID (mouse)CUX1_MOUSE
UniProt AC (human)P39880
(TFClass)
UniProt AC (mouse)P53564
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012196.251758.252157.251926.25
021022.751809.752395.752809.75
03784.0616.01512.05126.0
048022.00.00.016.0
050.00.00.08038.0
060.06744.00.01294.0
070.00.08038.00.0
088038.00.00.00.0
090.00.01.08037.0
10605.03179.02.04252.0
116094.0649.0861.0434.0
121798.02296.02672.01272.0
131105.752638.751982.752310.75
142004.251789.251890.252354.25
PFM
ACGT
010.2730.2190.2680.24
020.1270.2250.2980.35
030.0980.0770.1880.638
040.9980.00.00.002
050.00.00.01.0
060.00.8390.00.161
070.00.01.00.0
081.00.00.00.0
090.00.00.01.0
100.0750.3950.00.529
110.7580.0810.1070.054
120.2240.2860.3320.158
130.1380.3280.2470.287
140.2490.2230.2350.293
PWM
ACGT
010.089-0.1330.071-0.042
02-0.674-0.1050.1760.335
03-0.939-1.18-0.2840.936
041.383-6.797-6.797-4.703
05-6.797-6.797-6.7971.385
06-6.7971.21-6.797-0.44
07-6.797-6.7971.385-6.797
081.385-6.797-6.797-6.797
09-6.797-6.797-6.4291.385
10-1.1980.458-6.160.749
111.109-1.128-0.846-1.529
12-0.1110.1330.285-0.457
13-0.5960.272-0.0130.14
14-0.003-0.116-0.0610.158
Standard thresholds
P-value Threshold
0.001 0.78751
0.0005 2.30116
0.0001 7.284865