MotifCUX1.H12INVIVO.0.PM.A
Gene (human)CUX1
(GeneCards)
Gene synonyms (human)CUTL1
Gene (mouse)Cux1
Gene synonyms (mouse)Cutl1, Cux, Kiaa4047
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length13
ConsensusbbATTGAThhnbn
GC content31.49%
Information content (bits; total / per base)11.277 / 0.867
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words733

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (32) 0.882 0.939 0.799 0.902 0.799 0.903 2.705 3.863 231.887 364.06

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.989 0.98 0.984 0.973 0.956 0.934
best 0.995 0.99 0.993 0.987 0.99 0.983
Methyl HT-SELEX, 1 experiments median 0.992 0.985 0.989 0.981 0.984 0.974
best 0.992 0.985 0.989 0.981 0.984 0.974
Non-Methyl HT-SELEX, 3 experiments median 0.986 0.975 0.979 0.965 0.927 0.893
best 0.995 0.99 0.993 0.987 0.99 0.983

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.952 0.82 0.913 0.606
batch 2 0.919 0.778 0.882 0.62
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.1
HGNCHGNC:2557
MGIMGI:88568
EntrezGene (human)GeneID:1523
(SSTAR profile)
EntrezGene (mouse)GeneID:13047
(SSTAR profile)
UniProt ID (human)CUX1_HUMAN
UniProt ID (mouse)CUX1_MOUSE
UniProt AC (human)P39880
(TFClass)
UniProt AC (mouse)P53564
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01116.0147.0153.0317.0
0269.0107.0122.0435.0
03709.02.07.015.0
043.04.02.0724.0
0511.099.010.0613.0
061.02.0723.07.0
07713.05.06.09.0
0824.031.07.0671.0
09104.0317.024.0288.0
10345.0128.081.0179.0
11153.0158.0202.0220.0
12106.0153.0152.0322.0
13136.0139.0220.0238.0
PFM
ACGT
010.1580.2010.2090.432
020.0940.1460.1660.593
030.9670.0030.010.02
040.0040.0050.0030.988
050.0150.1350.0140.836
060.0010.0030.9860.01
070.9730.0070.0080.012
080.0330.0420.010.915
090.1420.4320.0330.393
100.4710.1750.1110.244
110.2090.2160.2760.3
120.1450.2090.2070.439
130.1860.190.30.325
PWM
ACGT
01-0.452-0.218-0.1790.544
02-0.962-0.532-0.4020.859
031.346-3.925-3.062-2.407
04-3.683-3.488-3.9251.367
05-2.682-0.608-2.7651.201
06-4.246-3.9251.366-3.062
071.352-3.325-3.185-2.854
08-1.975-1.734-3.0621.291
09-0.560.544-1.9750.449
100.629-0.355-0.805-0.023
11-0.179-0.1470.0970.181
12-0.541-0.179-0.1850.56
13-0.295-0.2740.1810.259
Standard thresholds
P-value Threshold
0.001 4.30041
0.0005 5.26506
0.0001 7.51982