MotifCUX1.H12INVITRO.2.P.C
Gene (human)CUX1
(GeneCards)
Gene synonyms (human)CUTL1
Gene (mouse)Cux1
Gene synonyms (mouse)Cutl1, Cux, Kiaa4047
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length19
ConsensusWdATKGWKKndYWbWKKhY
GC content41.56%
Information content (bits; total / per base)12.208 / 0.643
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (32) 0.599 0.841 0.432 0.819 0.583 0.821 1.371 7.71 4.69 118.721

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.675 0.612 0.642 0.594 0.606 0.574
best 0.734 0.659 0.706 0.64 0.666 0.616
Methyl HT-SELEX, 1 experiments median 0.695 0.628 0.662 0.608 0.623 0.586
best 0.695 0.628 0.662 0.608 0.623 0.586
Non-Methyl HT-SELEX, 3 experiments median 0.654 0.597 0.622 0.579 0.588 0.561
best 0.734 0.659 0.706 0.64 0.666 0.616

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.547 0.136 0.418 0.243
batch 2 0.554 0.17 0.417 0.264
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyCUX {3.1.9.2} (TFClass)
TFClass IDTFClass: 3.1.9.2.1
HGNCHGNC:2557
MGIMGI:88568
EntrezGene (human)GeneID:1523
(SSTAR profile)
EntrezGene (mouse)GeneID:13047
(SSTAR profile)
UniProt ID (human)CUX1_HUMAN
UniProt ID (mouse)CUX1_MOUSE
UniProt AC (human)P39880
(TFClass)
UniProt AC (mouse)P53564
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01716.017.045.0222.0
02169.0116.0575.0140.0
03864.058.047.031.0
0449.011.096.0844.0
0556.025.0653.0266.0
0649.080.0837.034.0
07784.078.044.094.0
0831.037.0573.0359.0
09108.081.0125.0686.0
10144.0278.0232.0346.0
11446.075.0374.0105.0
1235.0562.0120.0283.0
13198.051.034.0717.0
14153.0413.0254.0180.0
15289.058.067.0586.0
1685.030.0464.0421.0
1773.055.0762.0110.0
18196.0182.072.0550.0
1961.0213.0102.0624.0
PFM
ACGT
010.7160.0170.0450.222
020.1690.1160.5750.14
030.8640.0580.0470.031
040.0490.0110.0960.844
050.0560.0250.6530.266
060.0490.080.8370.034
070.7840.0780.0440.094
080.0310.0370.5730.359
090.1080.0810.1250.686
100.1440.2780.2320.346
110.4460.0750.3740.105
120.0350.5620.120.283
130.1980.0510.0340.717
140.1530.4130.2540.18
150.2890.0580.0670.586
160.0850.030.4640.421
170.0730.0550.7620.11
180.1960.1820.0720.55
190.0610.2130.1020.624
PWM
ACGT
011.048-2.598-1.684-0.118
02-0.388-0.760.829-0.574
031.235-1.439-1.642-2.04
04-1.602-2.985-0.9461.212
05-1.473-2.2430.9560.062
06-1.602-1.1251.204-1.952
071.138-1.15-1.706-0.967
08-2.04-1.8720.8260.36
09-0.83-1.113-0.6861.005
10-0.5470.105-0.0740.323
110.576-1.1880.401-0.858
12-1.9250.806-0.7270.123
13-0.231-1.563-1.9521.049
14-0.4870.4990.016-0.326
150.144-1.439-1.2980.848
16-1.066-2.0710.6150.518
17-1.215-1.491.11-0.812
18-0.241-0.315-1.2280.785
19-1.39-0.159-0.8870.911
Standard thresholds
P-value Threshold
0.001 4.22136
0.0005 5.10781
0.0001 6.98536