CTCF.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CTCF.H12RSNP.0.P.B
Gene (human)	CTCF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ctcf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	21
Consensus	nbdCCASYAGRKGGCRShvbn
GC content	67.52%
Information content (bits; total / per base)	19.447 / 0.926
Data sources	ChIP-Seq
Aligned words	850

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	238 (303)	0.984	0.995	0.968	0.991	0.978	0.993	6.473	7.937	593.143	978.18
Mouse	143 (168)	0.984	0.996	0.968	0.992	0.983	0.995	6.86	8.749	606.677	1085.137

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.843	0.835	0.704	0.704	0.603	0.622
Non-Methyl HT-SELEX, 1 experiments	best	0.843	0.835	0.704	0.704	0.603	0.622

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.026	304.569	0.169	0.135

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	CTCF-like {2.3.3.50} (TFClass)
TFClass ID	TFClass: 2.3.3.50.1
HGNC	HGNC:13723
MGI	MGI:109447
EntrezGene (human)	GeneID:10664 (SSTAR profile)
EntrezGene (mouse)	GeneID:13018 (SSTAR profile)
UniProt ID (human)	CTCF_HUMAN
UniProt ID (mouse)	CTCF_MOUSE
UniProt AC (human)	P49711 (TFClass)
UniProt AC (mouse)	Q61164 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	238 human, 143 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	CTCF.H12RSNP.0.P.B.pcm
PWM	CTCF.H12RSNP.0.P.B.pwm
PFM	CTCF.H12RSNP.0.P.B.pfm
Alignment	CTCF.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	CTCF.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	CTCF.H12RSNP.0.P.B_jaspar_format.txt
MEME format	CTCF.H12RSNP.0.P.B_meme_format.meme
Transfac format	CTCF.H12RSNP.0.P.B_transfac_format.txt
Homer format	CTCF.H12RSNP.0.P.B_homer_format_0.001.txt CTCF.H12RSNP.0.P.B_homer_format_0.0005.txt CTCF.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	74.0	284.0	74.0	418.0
02	115.0	169.0	413.0	153.0
03	247.0	51.0	445.0	107.0
04	21.0	807.0	9.0	13.0
05	5.0	836.0	2.0	7.0
06	682.0	26.0	98.0	44.0
07	16.0	587.0	243.0	4.0
08	87.0	415.0	17.0	331.0
09	804.0	9.0	21.0	16.0
10	6.0	2.0	837.0	5.0
11	229.0	8.0	596.0	17.0
12	19.0	25.0	580.0	226.0
13	6.0	4.0	837.0	3.0
14	11.0	20.0	798.0	21.0
15	45.0	776.0	9.0	20.0
16	197.0	18.0	625.0	10.0
17	49.0	598.0	168.0	35.0
18	106.0	287.0	62.0	395.0
19	300.0	212.0	282.0	56.0
20	95.0	206.0	225.0	324.0
21	260.0	179.0	193.0	218.0

PFM

	A	C	G	T
01	0.087	0.334	0.087	0.492
02	0.135	0.199	0.486	0.18
03	0.291	0.06	0.524	0.126
04	0.025	0.949	0.011	0.015
05	0.006	0.984	0.002	0.008
06	0.802	0.031	0.115	0.052
07	0.019	0.691	0.286	0.005
08	0.102	0.488	0.02	0.389
09	0.946	0.011	0.025	0.019
10	0.007	0.002	0.985	0.006
11	0.269	0.009	0.701	0.02
12	0.022	0.029	0.682	0.266
13	0.007	0.005	0.985	0.004
14	0.013	0.024	0.939	0.025
15	0.053	0.913	0.011	0.024
16	0.232	0.021	0.735	0.012
17	0.058	0.704	0.198	0.041
18	0.125	0.338	0.073	0.465
19	0.353	0.249	0.332	0.066
20	0.112	0.242	0.265	0.381
21	0.306	0.211	0.227	0.256

PWM

	A	C	G	T
01	-1.04	0.288	-1.04	0.673
02	-0.607	-0.227	0.661	-0.325
03	0.149	-1.402	0.735	-0.678
04	-2.245	1.329	-2.998	-2.68
05	-3.467	1.364	-4.062	-3.205
06	1.161	-2.046	-0.765	-1.545
07	-2.494	1.011	0.133	-3.629
08	-0.882	0.665	-2.439	0.44
09	1.325	-2.998	-2.245	-2.494
10	-3.327	-4.062	1.365	-3.467
11	0.074	-3.096	1.026	-2.439
12	-2.337	-2.083	0.999	0.061
13	-3.327	-3.629	1.365	-3.822
14	-2.826	-2.29	1.317	-2.245
15	-1.523	1.289	-2.998	-2.29
16	-0.075	-2.387	1.074	-2.908
17	-1.441	1.03	-0.233	-1.764
18	-0.688	0.298	-1.213	0.616
19	0.343	-0.002	0.281	-1.312
20	-0.795	-0.031	0.057	0.419
21	0.2	-0.17	-0.095	0.025

Standard thresholds

P-value	Threshold
0.001	0.80481
0.0005	2.17301
0.0001	5.07231