CTCF.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CTCF.H12INVIVO.0.P.B
Gene (human)	CTCF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ctcf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	20
Consensus	hddCCRShAGGKGGCGShvb
GC content	66.11%
Information content (bits; total / per base)	18.826 / 0.941
Data sources	ChIP-Seq
Aligned words	981

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	238 (303)	0.984	0.994	0.968	0.99	0.98	0.994	6.646	7.821	596.131	974.194
Mouse	143 (168)	0.982	0.994	0.966	0.989	0.985	0.995	7.058	8.819	617.016	1085.31

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.786	0.795	0.653	0.665	0.585	0.6
Non-Methyl HT-SELEX, 1 experiments	best	0.786	0.795	0.653	0.665	0.585	0.6

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.976	297.483	0.165	0.131

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	CTCF-like {2.3.3.50} (TFClass)
TFClass ID	TFClass: 2.3.3.50.1
HGNC	HGNC:13723
MGI	MGI:109447
EntrezGene (human)	GeneID:10664 (SSTAR profile)
EntrezGene (mouse)	GeneID:13018 (SSTAR profile)
UniProt ID (human)	CTCF_HUMAN
UniProt ID (mouse)	CTCF_MOUSE
UniProt AC (human)	P49711 (TFClass)
UniProt AC (mouse)	Q61164 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	238 human, 143 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	CTCF.H12INVIVO.0.P.B.pcm
PWM	CTCF.H12INVIVO.0.P.B.pwm
PFM	CTCF.H12INVIVO.0.P.B.pfm
Alignment	CTCF.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	CTCF.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	CTCF.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	CTCF.H12INVIVO.0.P.B_meme_format.meme
Transfac format	CTCF.H12INVIVO.0.P.B_transfac_format.txt
Homer format	CTCF.H12INVIVO.0.P.B_homer_format_0.001.txt CTCF.H12INVIVO.0.P.B_homer_format_0.0005.txt CTCF.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	128.0	304.0	79.0	470.0
02	163.0	161.0	453.0	204.0
03	277.0	49.0	513.0	142.0
04	62.0	873.0	25.0	21.0
05	6.0	967.0	4.0	4.0
06	766.0	18.0	125.0	72.0
07	28.0	643.0	299.0	11.0
08	194.0	365.0	36.0	386.0
09	913.0	24.0	32.0	12.0
10	1.0	2.0	976.0	2.0
11	388.0	1.0	590.0	2.0
12	26.0	16.0	551.0	388.0
13	5.0	2.0	973.0	1.0
14	20.0	12.0	910.0	39.0
15	55.0	890.0	1.0	35.0
16	244.0	6.0	716.0	15.0
17	59.0	668.0	217.0	37.0
18	85.0	353.0	68.0	475.0
19	410.0	233.0	296.0	42.0
20	122.0	189.0	330.0	340.0

PFM

	A	C	G	T
01	0.13	0.31	0.081	0.479
02	0.166	0.164	0.462	0.208
03	0.282	0.05	0.523	0.145
04	0.063	0.89	0.025	0.021
05	0.006	0.986	0.004	0.004
06	0.781	0.018	0.127	0.073
07	0.029	0.655	0.305	0.011
08	0.198	0.372	0.037	0.393
09	0.931	0.024	0.033	0.012
10	0.001	0.002	0.995	0.002
11	0.396	0.001	0.601	0.002
12	0.027	0.016	0.562	0.396
13	0.005	0.002	0.992	0.001
14	0.02	0.012	0.928	0.04
15	0.056	0.907	0.001	0.036
16	0.249	0.006	0.73	0.015
17	0.06	0.681	0.221	0.038
18	0.087	0.36	0.069	0.484
19	0.418	0.238	0.302	0.043
20	0.124	0.193	0.336	0.347

PWM

	A	C	G	T
01	-0.644	0.213	-1.118	0.647
02	-0.405	-0.417	0.61	-0.183
03	0.121	-1.583	0.734	-0.541
04	-1.355	1.265	-2.224	-2.386
05	-3.465	1.367	-3.765	-3.765
06	1.134	-2.528	-0.667	-1.209
07	-2.117	0.96	0.197	-2.966
08	-0.233	0.395	-1.879	0.451
09	1.309	-2.262	-1.991	-2.89
10	-4.508	-4.195	1.376	-4.195
11	0.456	-4.508	0.874	-4.195
12	-2.187	-2.634	0.806	0.456
13	-3.604	-4.195	1.373	-4.508
14	-2.431	-2.89	1.306	-1.803
15	-1.471	1.284	-4.508	-1.906
16	-0.005	-3.465	1.067	-2.693
17	-1.403	0.998	-0.121	-1.853
18	-1.047	0.362	-1.265	0.658
19	0.511	-0.051	0.187	-1.731
20	-0.691	-0.258	0.295	0.325

Standard thresholds

P-value	Threshold
0.001	0.84706
0.0005	2.25301
0.0001	5.20986