CTCF.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CTCF.H12INVITRO.0.P.B
Gene (human)	CTCF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ctcf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	bbdCCRShAGRKGRMRShv
GC content	63.83%
Information content (bits; total / per base)	14.1 / 0.742
Data sources	ChIP-Seq
Aligned words	819

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	238 (303)	0.983	0.993	0.967	0.988	0.977	0.991	6.493	7.426	592.149	953.215
Mouse	143 (168)	0.982	0.995	0.967	0.991	0.981	0.993	6.807	8.479	609.273	1067.538

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.959	0.96	0.755	0.777	0.623	0.662
Non-Methyl HT-SELEX, 1 experiments	best	0.959	0.96	0.755	0.777	0.623	0.662

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.972	297.571	0.161	0.129

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	CTCF-like {2.3.3.50} (TFClass)
TFClass ID	TFClass: 2.3.3.50.1
HGNC	HGNC:13723
MGI	MGI:109447
EntrezGene (human)	GeneID:10664 (SSTAR profile)
EntrezGene (mouse)	GeneID:13018 (SSTAR profile)
UniProt ID (human)	CTCF_HUMAN
UniProt ID (mouse)	CTCF_MOUSE
UniProt AC (human)	P49711 (TFClass)
UniProt AC (mouse)	Q61164 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	238 human, 143 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	CTCF.H12INVITRO.0.P.B.pcm
PWM	CTCF.H12INVITRO.0.P.B.pwm
PFM	CTCF.H12INVITRO.0.P.B.pfm
Alignment	CTCF.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	CTCF.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	CTCF.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	CTCF.H12INVITRO.0.P.B_meme_format.meme
Transfac format	CTCF.H12INVITRO.0.P.B_transfac_format.txt
Homer format	CTCF.H12INVITRO.0.P.B_homer_format_0.001.txt CTCF.H12INVITRO.0.P.B_homer_format_0.0005.txt CTCF.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	87.0	246.0	116.0	370.0
02	132.0	135.0	339.0	213.0
03	228.0	70.0	394.0	127.0
04	66.0	665.0	44.0	44.0
05	12.0	789.0	1.0	17.0
06	581.0	28.0	120.0	90.0
07	34.0	534.0	228.0	23.0
08	100.0	289.0	49.0	381.0
09	697.0	27.0	56.0	39.0
10	25.0	12.0	770.0	12.0
11	327.0	24.0	424.0	44.0
12	37.0	31.0	458.0	293.0
13	14.0	14.0	786.0	5.0
14	84.0	50.0	614.0	71.0
15	115.0	594.0	16.0	94.0
16	330.0	19.0	440.0	30.0
17	70.0	450.0	252.0	47.0
18	79.0	299.0	67.0	374.0
19	289.0	213.0	270.0	47.0

PFM

	A	C	G	T
01	0.106	0.3	0.142	0.452
02	0.161	0.165	0.414	0.26
03	0.278	0.085	0.481	0.155
04	0.081	0.812	0.054	0.054
05	0.015	0.963	0.001	0.021
06	0.709	0.034	0.147	0.11
07	0.042	0.652	0.278	0.028
08	0.122	0.353	0.06	0.465
09	0.851	0.033	0.068	0.048
10	0.031	0.015	0.94	0.015
11	0.399	0.029	0.518	0.054
12	0.045	0.038	0.559	0.358
13	0.017	0.017	0.96	0.006
14	0.103	0.061	0.75	0.087
15	0.14	0.725	0.02	0.115
16	0.403	0.023	0.537	0.037
17	0.085	0.549	0.308	0.057
18	0.096	0.365	0.082	0.457
19	0.353	0.26	0.33	0.057

PWM

	A	C	G	T
01	-0.845	0.182	-0.562	0.588
02	-0.435	-0.412	0.501	0.039
03	0.107	-1.058	0.651	-0.473
04	-1.115	1.172	-1.508	-1.508
05	-2.714	1.343	-4.345	-2.403
06	1.038	-1.94	-0.529	-0.812
07	-1.755	0.954	0.107	-2.124
08	-0.708	0.342	-1.404	0.617
09	1.219	-1.974	-1.275	-1.624
10	-2.046	-2.714	1.319	-2.714
11	0.465	-2.084	0.724	-1.508
12	-1.675	-1.843	0.801	0.356
13	-2.578	-2.578	1.339	-3.431
14	-0.879	-1.385	1.093	-1.044
15	-0.571	1.06	-2.458	-0.769
16	0.474	-2.301	0.761	-1.874
17	-1.058	0.783	0.206	-1.445
18	-0.939	0.376	-1.101	0.599
19	0.342	0.039	0.275	-1.445

Standard thresholds

P-value	Threshold
0.001	3.59826
0.0005	4.62741
0.0001	6.78931