CTCF.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CTCF.H12CORE.0.P.B
Gene (human)	CTCF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ctcf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	20
Consensus	hbRCCRShAGRKGGCGShvn
GC content	66.86%
Information content (bits; total / per base)	18.983 / 0.949
Data sources	ChIP-Seq
Aligned words	978

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	238 (303)	0.984	0.994	0.969	0.99	0.981	0.994	6.618	7.881	596.194	971.161
Mouse	143 (168)	0.983	0.994	0.966	0.989	0.984	0.995	7.025	8.806	613.494	1079.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.807	0.81	0.674	0.68	0.594	0.609
Non-Methyl HT-SELEX, 1 experiments	best	0.807	0.81	0.674	0.68	0.594	0.609

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.009	302.488	0.165	0.131

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	CTCF-like {2.3.3.50} (TFClass)
TFClass ID	TFClass: 2.3.3.50.1
HGNC	HGNC:13723
MGI	MGI:109447
EntrezGene (human)	GeneID:10664 (SSTAR profile)
EntrezGene (mouse)	GeneID:13018 (SSTAR profile)
UniProt ID (human)	CTCF_HUMAN
UniProt ID (mouse)	CTCF_MOUSE
UniProt AC (human)	P49711 (TFClass)
UniProt AC (mouse)	Q61164 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	238 human, 143 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	CTCF.H12CORE.0.P.B.pcm
PWM	CTCF.H12CORE.0.P.B.pwm
PFM	CTCF.H12CORE.0.P.B.pfm
Alignment	CTCF.H12CORE.0.P.B.words.tsv
Threshold to P-value map	CTCF.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	CTCF.H12CORE.0.P.B_jaspar_format.txt
MEME format	CTCF.H12CORE.0.P.B_meme_format.meme
Transfac format	CTCF.H12CORE.0.P.B_transfac_format.txt
Homer format	CTCF.H12CORE.0.P.B_homer_format_0.001.txt CTCF.H12CORE.0.P.B_homer_format_0.0005.txt CTCF.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	119.0	300.0	97.0	462.0
02	158.0	179.0	459.0	182.0
03	295.0	40.0	514.0	129.0
04	51.0	894.0	18.0	15.0
05	5.0	970.0	1.0	2.0
06	765.0	17.0	125.0	71.0
07	26.0	643.0	299.0	10.0
08	205.0	357.0	37.0	379.0
09	896.0	25.0	39.0	18.0
10	3.0	1.0	973.0	1.0
11	386.0	4.0	585.0	3.0
12	27.0	22.0	561.0	368.0
13	6.0	1.0	970.0	1.0
14	16.0	15.0	911.0	36.0
15	63.0	883.0	7.0	25.0
16	209.0	6.0	751.0	12.0
17	72.0	681.0	195.0	30.0
18	92.0	334.0	73.0	479.0
19	383.0	246.0	315.0	34.0
20	107.0	189.0	341.0	341.0

PFM

	A	C	G	T
01	0.122	0.307	0.099	0.472
02	0.162	0.183	0.469	0.186
03	0.302	0.041	0.526	0.132
04	0.052	0.914	0.018	0.015
05	0.005	0.992	0.001	0.002
06	0.782	0.017	0.128	0.073
07	0.027	0.657	0.306	0.01
08	0.21	0.365	0.038	0.388
09	0.916	0.026	0.04	0.018
10	0.003	0.001	0.995	0.001
11	0.395	0.004	0.598	0.003
12	0.028	0.022	0.574	0.376
13	0.006	0.001	0.992	0.001
14	0.016	0.015	0.931	0.037
15	0.064	0.903	0.007	0.026
16	0.214	0.006	0.768	0.012
17	0.074	0.696	0.199	0.031
18	0.094	0.342	0.075	0.49
19	0.392	0.252	0.322	0.035
20	0.109	0.193	0.349	0.349

PWM

	A	C	G	T
01	-0.713	0.203	-0.914	0.633
02	-0.433	-0.309	0.627	-0.293
03	0.187	-1.775	0.739	-0.633
04	-1.541	1.291	-2.525	-2.69
05	-3.601	1.373	-4.505	-4.192
06	1.136	-2.577	-0.664	-1.22
07	-2.184	0.963	0.2	-3.045
08	-0.175	0.376	-1.85	0.436
09	1.294	-2.221	-1.799	-2.525
10	-3.954	-4.505	1.376	-4.505
11	0.454	-3.762	0.868	-3.954
12	-2.149	-2.34	0.827	0.407
13	-3.462	-4.505	1.373	-4.505
14	-2.631	-2.69	1.31	-1.876
15	-1.336	1.279	-3.34	-2.221
16	-0.156	-3.462	1.117	-2.887
17	-1.206	1.02	-0.224	-2.049
18	-0.966	0.31	-1.192	0.669
19	0.446	0.006	0.252	-1.93
20	-0.817	-0.255	0.331	0.331

Standard thresholds

P-value	Threshold
0.001	0.75631
0.0005	2.17016
0.0001	5.14461