CREM.H12CORE.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CREM.H12CORE.1.P.C
Gene (human)	CREM (GeneCards)
Gene synonyms (human)
Gene (mouse)	Crem
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	18
Consensus	bbbbbKShddTGWhSThh
GC content	49.71%
Information content (bits; total / per base)	9.33 / 0.518
Data sources	ChIP-Seq
Aligned words	1002

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.793	0.813	0.69	0.732	0.794	0.816	3.235	4.087	101.745	129.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.706	0.648	0.655	0.613	0.606	0.582
Overall, 2 experiments	best	0.734	0.667	0.687	0.634	0.637	0.602
Methyl HT-SELEX, 1 experiments	median	0.734	0.667	0.687	0.634	0.637	0.602
Methyl HT-SELEX, 1 experiments	best	0.734	0.667	0.687	0.634	0.637	0.602
Non-Methyl HT-SELEX, 1 experiments	median	0.679	0.629	0.622	0.591	0.576	0.563
Non-Methyl HT-SELEX, 1 experiments	best	0.679	0.629	0.622	0.591	0.576	0.563

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	CREB-related {1.1.7} (TFClass)
TF subfamily	CREB-like {1.1.7.1} (TFClass)
TFClass ID	TFClass: 1.1.7.1.3
HGNC	HGNC:2352
MGI	MGI:88495
EntrezGene (human)	GeneID:1390 (SSTAR profile)
EntrezGene (mouse)	GeneID:12916 (SSTAR profile)
UniProt ID (human)	CREM_HUMAN
UniProt ID (mouse)	CREM_MOUSE
UniProt AC (human)	Q03060 (TFClass)
UniProt AC (mouse)	P27699 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	CREM.H12CORE.1.P.C.pcm
PWM	CREM.H12CORE.1.P.C.pwm
PFM	CREM.H12CORE.1.P.C.pfm
Alignment	CREM.H12CORE.1.P.C.words.tsv
Threshold to P-value map	CREM.H12CORE.1.P.C.thr
Motif in other formats
JASPAR format	CREM.H12CORE.1.P.C_jaspar_format.txt
MEME format	CREM.H12CORE.1.P.C_meme_format.meme
Transfac format	CREM.H12CORE.1.P.C_transfac_format.txt
Homer format	CREM.H12CORE.1.P.C_homer_format_0.001.txt CREM.H12CORE.1.P.C_homer_format_0.0005.txt CREM.H12CORE.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	44.0	389.0	127.0	442.0
02	95.0	171.0	400.0	336.0
03	98.0	576.0	184.0	144.0
04	117.0	241.0	172.0	472.0
05	132.0	179.0	531.0	160.0
06	133.0	113.0	613.0	143.0
07	123.0	151.0	663.0	65.0
08	554.0	185.0	118.0	145.0
09	417.0	93.0	282.0	210.0
10	371.0	107.0	265.0	259.0
11	39.0	27.0	43.0	893.0
12	30.0	12.0	911.0	49.0
13	550.0	48.0	79.0	325.0
14	443.0	395.0	41.0	123.0
15	61.0	76.0	790.0	75.0
16	57.0	121.0	14.0	810.0
17	133.0	539.0	48.0	282.0
18	460.0	229.0	33.0	280.0

PFM

	A	C	G	T
01	0.044	0.388	0.127	0.441
02	0.095	0.171	0.399	0.335
03	0.098	0.575	0.184	0.144
04	0.117	0.241	0.172	0.471
05	0.132	0.179	0.53	0.16
06	0.133	0.113	0.612	0.143
07	0.123	0.151	0.662	0.065
08	0.553	0.185	0.118	0.145
09	0.416	0.093	0.281	0.21
10	0.37	0.107	0.264	0.258
11	0.039	0.027	0.043	0.891
12	0.03	0.012	0.909	0.049
13	0.549	0.048	0.079	0.324
14	0.442	0.394	0.041	0.123
15	0.061	0.076	0.788	0.075
16	0.057	0.121	0.014	0.808
17	0.133	0.538	0.048	0.281
18	0.459	0.229	0.033	0.279

PWM

	A	C	G	T
01	-1.708	0.438	-0.673	0.565
02	-0.958	-0.379	0.465	0.292
03	-0.928	0.829	-0.306	-0.549
04	-0.754	-0.038	-0.373	0.63
05	-0.635	-0.333	0.748	-0.444
06	-0.627	-0.788	0.891	-0.555
07	-0.704	-0.502	0.969	-1.33
08	0.79	-0.301	-0.745	-0.542
09	0.507	-0.979	0.118	-0.175
10	0.391	-0.841	0.056	0.033
11	-1.823	-2.172	-1.73	1.266
12	-2.073	-2.911	1.286	-1.604
13	0.783	-1.624	-1.139	0.259
14	0.567	0.453	-1.775	-0.704
15	-1.392	-1.177	1.144	-1.19
16	-1.457	-0.72	-2.775	1.169
17	-0.627	0.763	-1.624	0.118
18	0.605	-0.089	-1.983	0.111

Standard thresholds

P-value	Threshold
0.001	4.77401
0.0005	5.52656
0.0001	7.09846