MotifCREB5.H12INVIVO.1.SM.B
Gene (human)CREB5
(GeneCards)
Gene synonyms (human)CREBPA
Gene (mouse)Creb5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnvATGAYGTMAb
GC content44.51%
Information content (bits; total / per base)13.97 / 1.164
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9471

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (10) 0.764 0.822 0.689 0.752 0.716 0.782 2.409 2.786 150.695 234.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.984 0.974 0.964 0.951 0.904 0.893
best 1.0 0.999 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 2 experiments median 0.998 0.997 0.997 0.995 0.983 0.98
best 1.0 0.999 1.0 0.999 0.999 0.999
Non-Methyl HT-SELEX, 4 experiments median 0.887 0.887 0.778 0.785 0.692 0.705
best 1.0 0.999 0.999 0.999 0.998 0.998

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.873 0.529 0.835 0.515
batch 2 0.927 0.847 0.863 0.565
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyJun-related {1.1.1} (TFClass)
TF subfamilyATF2 {1.1.1.3} (TFClass)
TFClass IDTFClass: 1.1.1.3.3
HGNCHGNC:16844
MGIMGI:2443973
EntrezGene (human)GeneID:9586
(SSTAR profile)
EntrezGene (mouse)GeneID:231991
(SSTAR profile)
UniProt ID (human)CREB5_HUMAN
UniProt ID (mouse)CREB5_MOUSE
UniProt AC (human)Q02930
(TFClass)
UniProt AC (mouse)Q8K1L0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
011397.752554.752584.752933.75
022093.751381.754843.751151.75
036896.029.02526.020.0
040.036.01.09434.0
050.00.09013.0458.0
069462.00.01.08.0
074.06643.0263.02561.0
08431.031.09009.00.0
0945.076.06.09344.0
103310.05988.0118.055.0
117687.0329.01132.0323.0
12588.252636.251384.254862.25
PFM
ACGT
010.1480.270.2730.31
020.2210.1460.5110.122
030.7280.0030.2670.002
040.00.0040.00.996
050.00.00.9520.048
060.9990.00.00.001
070.00.7010.0280.27
080.0460.0030.9510.0
090.0050.0080.0010.987
100.3490.6320.0120.006
110.8120.0350.120.034
120.0620.2780.1460.513
PWM
ACGT
01-0.5260.0760.0880.214
02-0.123-0.5380.715-0.72
031.068-4.3270.065-4.667
04-6.943-4.125-6.581.382
05-6.943-6.9431.336-1.639
061.385-6.943-6.58-5.44
07-5.9321.031-2.190.078
08-1.699-4.2651.336-6.943
09-3.914-3.41-5.6561.372
100.3350.927-2.981-3.723
111.177-1.968-0.737-1.986
12-1.390.107-0.5360.719
Standard thresholds
P-value Threshold
0.001 2.278585
0.0005 3.760525
0.0001 6.838265