MotifCREB5.H12INVIVO.0.P.B
Gene (human)CREB5
(GeneCards)
Gene synonyms (human)CREBPA
Gene (mouse)Creb5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnRTGAKGTMAK
GC content36.05%
Information content (bits; total / per base)11.335 / 1.03
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (10) 0.767 0.833 0.701 0.781 0.753 0.816 2.758 3.179 140.833 214.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.954 0.935 0.908 0.888 0.824 0.813
best 1.0 0.999 0.999 0.998 0.993 0.991
Methyl HT-SELEX, 2 experiments median 0.997 0.996 0.993 0.99 0.958 0.954
best 1.0 0.999 0.999 0.998 0.993 0.991
Non-Methyl HT-SELEX, 4 experiments median 0.841 0.824 0.722 0.717 0.638 0.644
best 0.995 0.992 0.991 0.986 0.983 0.975

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.842 0.428 0.348 0.189
batch 2 0.892 0.795 0.453 0.288
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyJun-related {1.1.1} (TFClass)
TF subfamilyATF2 {1.1.1.3} (TFClass)
TFClass IDTFClass: 1.1.1.3.3
HGNCHGNC:16844
MGIMGI:2443973
EntrezGene (human)GeneID:9586
(SSTAR profile)
EntrezGene (mouse)GeneID:231991
(SSTAR profile)
UniProt ID (human)CREB5_HUMAN
UniProt ID (mouse)CREB5_MOUSE
UniProt AC (human)Q02930
(TFClass)
UniProt AC (mouse)Q8K1L0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01346.0159.0319.0176.0
02662.0115.0181.042.0
0339.06.011.0944.0
043.011.0806.0180.0
05914.029.026.031.0
0676.038.0263.0623.0
0714.0117.0824.045.0
0821.0104.027.0848.0
09297.0667.011.025.0
10970.013.02.015.0
1130.0117.0119.0734.0
PFM
ACGT
010.3460.1590.3190.176
020.6620.1150.1810.042
030.0390.0060.0110.944
040.0030.0110.8060.18
050.9140.0290.0260.031
060.0760.0380.2630.623
070.0140.1170.8240.045
080.0210.1040.0270.848
090.2970.6670.0110.025
100.970.0130.0020.015
110.030.1170.1190.734
PWM
ACGT
010.323-0.4490.242-0.348
020.97-0.769-0.32-1.75
03-1.821-3.484-2.9851.324
04-3.975-2.9851.166-0.326
051.291-2.103-2.206-2.04
06-1.175-1.8460.050.909
07-2.773-0.7521.188-1.684
08-2.405-0.867-2.1711.217
090.1710.977-2.985-2.243
101.351-2.839-4.213-2.711
11-2.071-0.752-0.7351.073
Standard thresholds
P-value Threshold
0.001 4.375965
0.0005 5.31567
0.0001 7.21124